Christopher Hunter joins Chemical Science as Associate Editor

Chemical Science is pleased to welcome Christopher Hunter as Associate Editor for Physical Organic chemistry.  

Biography
Christopher Hunter is Herchel Smith Professor of Organic Chemistry at the University of Cambridge. Originally from New Zealand, he moved to Northern Ireland at the age of four and completed his early education there.  After receiving his undergraduate degree and PhD from Churchill College, Cambridge, he returned to his native New Zealand for a couple of years to lecture at the University of Otago. In 1991 he moved back to the UK, joining the University of Sheffield first as Lecturer and then as Professor, before taking up his current post at the University of Cambridge in September 2014.  

Research
The Hunter Group’s aim is to establish a reliable set of rules that can be used for the design of non-covalent systems. Their research focuses on four main areas of development:
1. Fundamental investigations of the nature of intermolecular interactions
2. Molecular design of functional assemblies
3. Development of new methods for studying solvation and co-operativity
4. Computer modelling of intermolecular interactions  

Awards
Chris’s recent awards include the RSC Physical Organic Chemistry Award (2011) and the RSC Tilden Prize (2009). In 2008 he was elected a Fellow of the Royal Society.  

Publications
You can read some of the most recent work from the Hunter group in Chemical Science – click on the links below to get to the articles. All are either Open Access or free to access until 24th March: 

The flexibility–complementarity dichotomy in receptor–ligand interactions
Hongmei Sun, Christopher A. Hunter and Eva Marina Llamas  
Chem. Sci., 2015, 6, 1444-1453
DOI: 10.1039/C4SC03398A, Edge Article
OA icon Open Access
 
pH-dependent binding of guests in the cavity of a polyhedral coordination cage: reversible uptake and release of drug molecules
William Cullen, Simon Turega, Christopher A. Hunter and Michael D. Ward  
Chem. Sci., 2015, 6, 625-631
DOI: 10.1039/C4SC02090A, Edge Article
OA icon Open Access
 
Applications of dynamic combinatorial chemistry for the determination of effective molarity
Maria Ciaccia, Irene Tosi, Laura Baldini, Roberta Cacciapaglia, Luigi Mandolini, Stefano Di Stefano and Christopher A. Hunter  
Chem. Sci., 2015, 6, 144-151
DOI: 10.1039/C4SC02347A, Edge Article
OA icon Open Access
 
A solvent-resistant halogen bond
Craig C. Robertson, Robin N. Perutz, Lee Brammer and Christopher A. Hunter  
Chem. Sci., 2014, 5, 4179-4183
DOI: 10.1039/C4SC01746C, Edge Article
OA icon Open Access
 
Quantification of solvent effects on molecular recognition in polyhedral coordination cage hosts
Martina Whitehead, Simon Turega, Andrew Stephenson, Christopher A. Hunter and Michael D. Ward  
Chem. Sci., 2013, 4, 2744-2751
DOI: 10.1039/C3SC50546D, Edge Article 
OA icon Open Access

A surface site interaction model for the properties of liquids at equilibrium
Christopher A. Hunter  
Chem. Sci., 2013, 4, 1687-1700
DOI: 10.1039/C3SC22124E, Edge Article
From themed collection Physical Chemistry  

van der Waals interactions in non-polar liquids
Christopher A. Hunter  
Chem. Sci., 2013, 4, 834-848
DOI: 10.1039/C2SC21666C, Edge Article
From themed collection Physical Chemistry  

Chris is now accepting submissions to Chemical Science in the area of physical organic chemistry.  Submit your high-impact research to his Editorial Office.  


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Chemical Science welcomes Vy Dong as Associate Editor

Chemical Science is delighted to welcome Vy Dong of UC Irvine as Associate Editor in the area of Organic Chemistry.

Vy DongBiography
Vy Dong grew up in Big Spring, Texas and Anaheim, California. After graduating from the University of California, Irvine, she joined David MacMillan‘s group at UC Berkeley, moving with his group to Caltech to complete her doctoral studies. She began her independent academic career at the University of Toronto in 2006, where she was promoted with tenure and named the Adrian Brook Professor. After six years in Canada, Vy returned to the United States to assume a professorship at her alma mater, UC Irvine.

In 2013 we interviewed Vy for Chemistry Worldread the full interview to find out why Vy chose to pursue a career in chemistry, how she comes up with ideas for new projects, and what she loves about her job.

Research
Professor Dong’s research group at UC Irvine is interested in new reaction methods, enantioselective catalysis, and natural product synthesis. Specifically, the group looks at finding ways to directly convert carbon-hydrogen bonds into other functional groups, use carbon dioxide as a raw material, and make biologically active heterocycles.

Publications
We’ve made some of the Dong Research Group’s Chemical Science articles free to access until 18th March – click on the titles below to get to the articles*:

Mechanistic insights into hydroacylation with non-chelating aldehydes
Stephen K. Murphy, Achim Bruch and Vy M. Dong
Chem. Sci., 2015,6, 174-180, DOI: 10.1039/C4SC02026J, Edge Article
OA icon Open Access

β-hydroxy ketones prepared by regioselective hydroacylation
Stephen K. Murphy, Matthew M. Coulter and Vy M. Dong
Chem. Sci., 2012,3, 355-358, DOI: 10.1039/C1SC00634G, Edge Article

Ru-catalyzed activation of sp3 C–O bonds: O– to N-alkyl migratory rearrangement in pyridines and related heterocycles
Charles S. Yeung, Tom H. H. Hsieh and Vy M. Dong
Chem. Sci., 2011,2, 544-551, DOI: 10.1039/C0SC00498G, Edge Article

Nitrogen-directed ketone hydroacylation: Enantioselective synthesis of benzoxazecinones
Hasan A. Khan, Kevin G. M. Kou and Vy M. Dong
Chem. Sci., 2011,2, 407-410, DOI: 10.1039/C0SC00469C, Edge Article

Vy is now accepting submissions to Chemical Science in the area of organic chemistry. Submit your high-impact research to her Editorial Office.

*Access is free through a registered RSC account

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Photosynthesis takes the high road

Jason Woolford writes about a hot Chemical Science article for Chemistry World

Understanding biological water oxidation is central to achieving artificial photosynthesis and providing cheap and efficient hydrogen production. However, cracking the mystery of such a complex system has resulted in two competing oxidation state schemes, accompanied by controversy and debate over which is correct. Now, Dimitrios Pantazis, of the Max Planck Institute for Chemical Energy Conversion in Germany, and his colleagues feel they have proven one scheme more valid than the other.


Read the full article in Chemistry World»

Read the original journal article in Chemical Science – it’s Open Access and free to read:
Metal oxidation states in biological water splitting

Vera Krewald, Marius Retegan, Nicholas Cox, Johannes Messinger, Wolfgang Lubitz, Serena DeBeer, Frank Neese and Dimitrios A. Pantazis  
Chem. Sci., 2015, Advance Article
DOI: 10.1039/C4SC03720K, Edge Article

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Hot Chemical Science articles for January

We hope you enjoy reading some of the most recent referee-recommended articles from Chemical Science – all Open Access unless otherwise stated   

Solid state organic amine detection in a photochromic porous metal organic framework
Arijit Mallick, Bikash Garai, Matthew A. Addicoat, Petko St. Petkov, Thomas Heine and Rahul Banerjee  
Chem. Sci., 2015, 6, 1420-1425
DOI: 10.1039/C4SC03224A, Edge Article
Open Access    

C4SC03224A ga   


Synergistic cascade catalysis by metal nanoparticles and Lewis acids in hydrogen autotransfer
Gerald C. Y. Choo, Hiroyuki Miyamura and Shū Kobayashi  
Chem. Sci., 2015, Advance Article
DOI: 10.1039/C4SC03627A, Edge Article
Open Access   

C4SC03627A ga   


Critical analysis of the limitations of Bleaney’s theory of magnetic anisotropy in paramagnetic lanthanide coordination complexes
Alexander M. Funk, Katie-Louise N. A. Finney, Peter Harvey, Alan M. Kenwright, Emily R. Neil, Nicola J. Rogers, P. Kanthi Senanayake and David Parker  
Chem. Sci., 2015, Advance Article
DOI: 10.1039/C4SC03429E, Edge Article
Open Access   

C4SC03429E ga   


The role of πσ* states in the photochemistry of heteroaromatic biomolecules and their subunits: insights from gas-phase femtosecond spectroscopy
Gareth M. Roberts and Vasilios G. Stavros 
Journal Article
Chem. Sci., 2014, 5, 1698-1722
DOI: 10.1039/C3SC53175A, Perspective
Free to access until 2nd March   

C3SC53175A ga   


Thermoresponsive organometallic arene ruthenium complexes for tumour targeting
Catherine M. Clavel, Emilia Păunescu, Patrycja Nowak-Sliwinska and Paul J. Dyson  
Chem. Sci., 2014, 5, 1097-1101
DOI: 10.1039/C3SC53185F, Edge Article
Open Access   

C3SC53185F ga   


Polyunsaturated fatty acid biosynthesis in myxobacteria: different PUFA synthases and their product diversity
Katja Gemperlein, Shwan Rachid, Ronald O. Garcia, Silke C. Wenzel and Rolf Müller  
Chem. Sci., 2014, 5, 1733-1741
DOI: 10.1039/C3SC53163E, Edge Article
Free to access until 2nd March   

C3SC53163E ga

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Challenges in Chemical Biology – oral abstract deadline: 23 February

Don’t miss your chance to be part of this significant event – submit today!


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Oral abstract submission – deadline extended to 23 February 2015

We invite you to join us at Challenges in Chemical Biology (ISACS16), the 16th conference in the highly successful International Symposia on Advancing the Chemical Sciences (ISACS) series.

The conference will be held at the ETH, Zurich, Switzerland from 15-18 June 2015.

Take advantage of this excellent opportunity to showcase your latest research alongside the following leading scientists from across the globe – submit your abstract today.

Confirmed invited speakers:

Shankar Balasubramanian, University of Cambridge, UK
Annette Beck-Sickinger, Leipzig University, Germany
Peng Chen, Peking University, China
Dorothea Fiedler, Princeton University, USA
Kai Johnsson, EPFL Switzerland, Switzerland
Carsten Schultz, European Molecular Biology Laboratory, Germany
Scott Sternson, Howard Hughes Medical Institute, USA
John Sutherland, MRC Laboratory of Molecular Biology, UK
David Tirrell, California Institute of Technology, USA
Yasuteru Urano, University of Tokyo, Japan
Wilfred van der Donk, University of Illinois, USA

We look forward to welcoming you to Zurich in June 2015.

Professor Hema Wennemers
Conference Chair
Dr Heather Montgomery
Deputy Editor, Chemical Science
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Smart nanoparticles take aim at cancer cells

Thadchajini Retneswaran writes about a hot Chemical Science article for Chemistry World

Scientists in China have developed an intelligent nanoparticle system that delivers a chemotherapeutic and radiosensitiser drug directly to the nucleus of cancer cells. Tests suggest this intranuclear radiosensitisation technique could intensify the effects of radiotherapy.

Along with radiotherapy, chemotherapy assumes a frontline position in the battle against cancer. However, many drugs fail to enter cancer cell nuclei when they should. This often leads to multidrug resistance in tumours and a diminished response to radiotherapy.


Read the full article in Chemistry World»

Read the original journal article for free in Chemical Science:
Design of An Intelligent Sub-50 nm Nuclear-targeting Nanotheranostic System for Imaging Guided Intranuclear Radiosensitization
Wenpei Fan, Bo Shen, Wenbo Bu, Xiangpeng Zheng, Qianjun He, Zhaowen Cui, Kuaile Zhao, Shengjian Zhang and Jianlin Shi  
 Chem. Sci., 2014, Accepted Manuscript
DOI: 10.1039/C4SC03080J, Edge Article

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Daniel Nocera – our new Chemical Science Editor-in-Chief

We are delighted to announce Professor Daniel Nocera as the new Editor-in-Chief of Chemical Science. Daniel Nocera, the Patterson Rockwood Professor of Energy at Harvard University, has a diverse research programme and is recognised, internationally, as a pioneer and leading expert in the field of solar energy conversion.

Professor Nocera’s group has recently accomplished a solar fuels process that captures many of the elements of photosynthesis – he has now translated this science to produce the artificial leaf. This exciting discovery sets the stage for a storage mechanism for the distributed deployment of solar energy.

As we thank Professor David MacMillan for his valuable contributions to Chemical Science since its launch in 2010, we extend a warm welcome to Professor Nocera as he leads the journal towards continued success and excellence.

Professor Nocera joins us in inviting you to read Chemical Science’s first Open Access articles in Issue 1 for 2015 – one hundred cutting-edge articles showcasing exceptional research across the chemical sciences. For a limited time, these have been gathered under broad subject areas to show significant breakthroughs in each field:

Analytical Chemistry

Chemical Biology and Medicinal Chemistry

Organic Chemistry

Catalysis

Energy and Physical Chemistry

Materials

Nanoscience

Inorganic Chemistry

Chemical Science is the Royal Society of Chemistry’s flagship journal, publishing research articles of exceptional significance and high-impact reviews from across the chemical sciences. The journal’s latest (2013) Impact Factor is 8.6. Research in Chemical Science is not only of the highest quality but also has excellent visibility; this is reflected in our latest citation profile.

Submit your exceptional research to Chemical Science today!

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Spinach chlorophyll activates polymer production line

Elisabeth Ratcliffe writes about a hot Chemical Science article for Chemistry World

Inspired by nature, scientists in Australia have united light and chlorophyll to generate a range of polymers that have biomedical applications.

During photosynthesis, chlorophyll is activated by visible light, and an electron is promoted from its ground state to an excited state. In plants, this excited electron goes on to react with carbon dioxide and water, via photoinduced electron transfer (PET). However, in the system devised by Cyrille Boyer and colleagues at the University of New South Wales, the excited electron is donated to a monomer, generating a radical, which then goes on to further react and generate polymers through a process known as living radical polymerisation.


Read the full article in Chemistry World»

Read the original journal article in Chemical Science – it’s free to access:
Utilizing the electron transfer mechanism of chlorophyll a under light for controlled radical polymerization
Sivaprakash Shanmugam, Jiangtao Xu and Cyrille Boyer  
Chem. Sci., 2015, Advance Article
DOI: 10.1039/C4SC03342F, Edge Article

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Synthetic Porphyrin Nanorings as Biomimetic Light Harvesters

In this Chemical Science Edge Article, the Anderson group and colleagues at the Universitiy of Oxford describe ultra-fast light harvesting materials which function in a similar way to various natural light harvesters, like, for example, those found in the chlorophyll assemblies of purple bacteria. These materials represent excellent candidates for use in next generation carbon based solar cells. 

The materials, which may contain up to 24 porphyrin units separated by conjugating butadiyne bridges, can measure up to 10nm in diameter. Recent advances in template directed synthesis mean these molecules have become more accessible.

Barriers to energy delocalisation are overcome due to distortions that occur in the molecular structure. A rigidifying template was used to probe the effect of distortions – without a coordinating constraint present, significantly different behaviour was observed, underlying the importance of flexibility to the behaviour observed.

24 prophyrin containing nanoring, and an example of a 6 unit ring containing a rigidifying template

 

Physical techniques were used to characterise the complex phenomena being observed, including time resolved photoluminescence spectroscopy, using femtosecond LASERs and steady state fluorescence. Further information about electronic structure was gained by comparing spectra of the ring structures with those of  linear oligomeric analogues. 

The authors describe synthetic materials which show a level of light harvesting and rapid energy delocalising ability, usually only seen in natural systems. The promise of technological applications which exploit these properties will drive the study of the fundamental physics and chemistry of such fascinating systems. 

Read this Chemical Science Edge Article today: 

Ultrafast Delocalisation of excitation in synthetic light-harvesting nanorings
Chaw-Keong Yong, Patrick Parkinson, Dmitry V. Kondratuk, Wei-Hsin Chen, Andrew Stannard, Alex Summerfield, Johannes K. Sprafke, Melanie C. O’Sullivan, Peter H. Beton, Harry L. Anderson and Laura M. Herz.
DOI: 10.1039/C4SC02424A

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Benchtop NMR gives feedback in flow

Hugh Cowley writes about a hot Chemical Science article for Chemistry World

Flow reactors are edging towards self-regulation, thanks to researchers in the UK.

Inspired by previous self-optimised flow systems with in-line analytical monitoring, Lee Cronin’s group at the University of Glasgow has extended this concept so that multinuclear and 2D NMR can be performed in the fume hood.


Read the full article in Chemistry World»

Read the original journal article in Chemical Science:
A Self Optimizing Synthetic Organic Reactor System Using Real-time In-line NMR spectroscopy
Lee Cronin, Victor Sans, Luzian Porwol and Vincenza Dragone  
Chem. Sci., 2014, Accepted Manuscript
DOI: 10.1039/C4SC03075C, Edge Article

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