Metal catalysed asymmetric allylic alkylation (AAA) reactions have been an extensively studied and fruitful area of research in organic chemistry. The use of heteroatom-centered nucleophiles in this reaction is a powerful method for asymmetric C–X (X = heteroatom) bond formation.
In issue 4’s Perspective, Barry Trost and colleagues summarise developments and applications of metal catalysed AAA reactions employing heteroatom nucleophiles.
To keep up-to-date with the latest articles from Chemical Science, sign up for the Chemical Science e-alert. For details about submitting your own high quality articles, please visit the website or contact the Editorial Office.
