Chemical Communications Blog

A 5am start was always going to be tough, particularly after such a successful event in Kyoto. That said, with cases packed, we headed to Kansai Airport…. next stop Beijing!

After a three hour flight, the ChemComm International delegation arrived at Beijing International Airport where we had a four hour layover. After lunch, we were joined by the RSC Publisher for China, Dr Daping Zhang, and Professor Keiji Maruoka, the final international speaker for the next two events. The flight to Lanzhou was smooth and, to our delight, we were met by the former director of the Key State Laboratory and member of the Chinese Academy of Sciences, Professor Yong-Qiang Tu. Following a buffet dinner accompanied by excellent regional red wine, the speakers retired early with one eye on the second symposium. 

Professor Tu opened events and chaired the first session, inviting Professor Xinhe Bao to the stage. Professor Bao gave a beautiful overview on some of his very detailed studies into heterogenous catalysis within nanotubes and other nano-confined systems. Using nobel metals or metals such as iron or nickel, it was shown that the conversation of syngas was much more efficient inside the tube than outside. The subject of the session then switched to metal-free homogenous catalysis, as Professor Maruoka spoke about some of his latest results in the field of organocatalysis. As you would expect, high enatiomeric excesses and yields were the order of the day.

 Following coffee, Professor Veronique Gouverneur gave another whistle-stop tour of her group’s latest organofluorine chemistry and the formation of  C–F bonds using palladium and gold homogenous catalysis.

As in Kyoto, the speakers worked hard over lunch analysing the 80 posters on show. They covered everything from organic methodology, to total synthesis, organic materials and supramolecular chemistry. If they thought judging them was tough in Kyoto, it proved even more so in Lanzhou! Unfortunately, Professor Ben Feringa was unable to act as a judge, because, due to a last minute laptop crisis, his presentation was being transferred to a spare laptop, with his own laptop in pieces, being fixed by helpful student Mr Woo.

After lunch, the conference switched gears to total synthesis. Professor Dawei Ma spoke first about the total synthesis of galbulimima alkaloids and communesins. Professor Ma was followed by Professor Viresh Rawal, who gave a different talk to that described in the programme. Professor Rawal described his recent total synthesis of Pederin and Mycalamide B, both part of the Pederin family of natural products isolated from the beetle Paederus fuscipas. He also introduced initial work looking at bioactivity of Mycalamide in cells, carried out with Milan Mrksich. 

For the final session, the audience were treated to a masterclass from Ben Feringa on molecular motors and switches. This was only made possible by Mr Woo, who had rebuilt his computer, replacing a transistor, and bingo! His synthetic motors, inspired by nature, are unidirectional with the direction controlled by the enantiomer used. By adding legs, the motors can be bound to gold surfaces and then used to change the orientation of liquid crystal films. A great talk and even Professor Bao, the session Chair, could not bring himself to cut it short. Thank goodness for Mr Woo! The final talk of the day was presented by Professor Deqing Zhang on tetrathiafulvalene-based switchable molecular systems towards functional materials. 

The evening social events were as memorable as the science, with the speakers joined by 50 or so guests including the vice Dean of Lanzhou University. The Chinese banquet was enhanced with locally produced red wine and Chinese liquor (only to be drunk in multiples of three – Chinese style…kambai). After many toasts and speeches, the speakers were taken to a local pub for some traditional Chinese music. The night was not done, however, as we then moved to a Tibetan bar. The speakers were told to expect local singing and dancing. Little did they know that they would be involved! After being sung to, each speaker was presented with a white Hada. What a great way to end such a action-packed day.

Next stop Tianjin for the final event of three…..

Robert Eagling

The 5th International ChemComm Symposium got off to an excellent start in Kyoto, Japan, on Monday (16th May) under the Chairmanship of ChemComm Editorial Board member and distinguished Professor Keiji Maruoka (Kyoto University).

World leading authorities from the USA, UK, the Netherlands, China and Japan arrived on Sunday in time to be treated to a ten course western-style dinner. The dinner was a perfect start to proceedings but even the ten courses could not over-shadow the science that was to follow.

With an audience in excess of 100, I opened the symposium and thanked the local organisers, speakers and poster presenters. Special thanks were also given to Professor Maruoka for all his support in organising the event. As the first session Chair, Professor Maruoka then got things underway.

Professor Tsutomu Katsuki (Kyushu University) was up first, speaking initially about oxidation chemistry using ruthenium but then moving, like nature, to iron, for example. He was followed by Professor Kuiling Ding (Shanghai Institute of Organic Chemistry) who gave a talk of two halves, covering his group’s ongoing efforts to overcome the challenging issues in both homogenous and heterogeneous asymmetric catalysis.

A quick stop for refreshments was followed by Professor Véronique Gouverneur (University of Oxford) who spoke about her ongoing efforts to develop transition metal-catalysed reactions to generate C–F bonds. Not easy, but made even more challenging by the fact that the methods need to be incredibly quick so they can be used to incorporate hot [18F], which has a very short half-life. Such [18F] labelled compounds are used in positron emission tomography.

Over lunch, the seven speakers interacted with the 35 poster presenters, putting them through their paces, with the five lucky winners scheduled to be announced at the end of the day.

The pace of the event did not slow after lunch. Professor Viresh Rawal (University of Chicago) wowed a packed auditorium with some of his latest results using H-bonded systems for asymmetric catalysis. Before the break, Professor Zhengfeng Xi (Peking University) spoke about the synthesis, unique reactivity, cooperative effect and applications of organo-di-lithio reagents.

The symposium was closed first by Professor Atsuhiro Osuka (Kyoto University), who spoke about some of his beautiful results in the area of Möbius porphrin chemistry, and then by Professor Ben Feringa (University of Groningen). Professor Feringa gave a wonderful overview of some of the ongoing research in his lab exploring chiral space in asymmetric catalysis. Some highlights included the latest examples of C–H and C–C bond formation using monodentate phosphoramidite ligands and also new results in the field of asymmetric catalysis using DNA with his colleague Professor Gerard Roelfes. The later certainly generated a number of interesting questions about the length and sequence requirements of the DNA involved in the reactions.

After the formal poster prize presentations, the speakers and organising committee were treated to a traditional Japanese meal. Before dinner, the historic nature of the Japanese tea ceremony was explained in detail and served to the group by a Maiko (a young training Geiko). Through dinner, the speakers were also treated to some traditional Japanese singing and dancing performed by the Maiko. The music and dance showcased the four seasons of Kyoto.

The dinner finished with the speakers retiring to bed in preparation for their early flight first to Beijing and then Lanzhou, the next venue for the second of three ChemComm symposia.

Robert Eagling