The importance of chemistry in sequencing nucleic acids

 

Solid phase DNA sequencing

Chemistry has played a vital role towards making routine, affordable sequencing of human genomes a reality. Leading UK scientist, Shankar Balasubramanian, provides a compelling review of the last 60 years, from the Sanger sequencing method through to the human genome project. In particular, Balasubramanian focuses on the achievements of Solexa (latterly, Illumina) on the modern developments of high throughput nucleic acid sequencing that originated in Cambridge, in the UK.
   

In association with the International Year of Chemistry (IYC), this Highlight in Chemistry emphasises the importance of chemistry and how it continues to contribute towards many other fields, most notably the biological and biomedical sciences. This sequencing approach is helping to transform science and offers intriguing prospects for the future of medicine.

Fancy reading more? Download the ChemComm Highlight, which will be free to access until the 1st July 2011.

 For your info, ChemComm is publishing Highlights in Chemistry articles throughout 2011, which has been recognised as an official activity for celebrating the IYC. Take a look at the IYC website to keep up-to-date on what else is happening throughout 2011 to celebrate the achievements of chemistry and its contributions to the well-being of humankind.

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