Top 25 most downloaded Chemical Science articles October–December 2014

Chemical Science Issue 1, 2015 front coverHave you read the 25 most downloaded Chemical Science articles from October–December 2014?

An anti-cancer trinuclear ruthenium(III) complex with 2-thiosalicylate ligands attenuates Wnt-β-catenin signaling
Sharon Lai-Fung Chan, Raymond Wai-Yin Sun, Mei-Yuk Choi, Yibo Zeng, Lam Shek, Stephen Sin-Yin Chui and Chi-Ming Che  
DOI:10.1039/C1SC00203A

Selective affinity-based probe for oncogenic kinases suitable for live cell imaging
Claudio Zambaldo, Kalyan K. Sadhu, Ganesan Karthikeyan, Sofia Barluenga, Jean-Pierre Daguer and Nicolas Winssinger
DOI: 10.1039/C3SC21856B

De novo design and optimization of Aurora A kinase inhibitors
Tiago Rodrigues, Filip Roudnicky, Christian P. Koch, Takayuki Kudoh, Daniel Reker, Michael Detmar and Gisbert Schneider  
DOI: 10.1039/C2SC21842A

A high-spin square-planar Fe(II) complex stabilized by a trianionic pincer-type ligand and conclusive evidence for retention of geometry and spin state in solution
M. E. Pascualini, N. V. Di Russo, A. E. Thuijs, A. Ozarowski, S. A. Stoian, K. A. Abboud, G. Christou and A. S. Veige  
DOI: 10.1039/C4SC02634A
Open Access

Macrocycles: lessons from the distant past, recent developments, and future directions
Andrei K. Yudin
DOI: 10.1039/C4SC03089C
Open Access

Carbon–hydrogen (C–H) bond activation at PdIV: a Frontier in C–H functionalization catalysis
Joseph J. Topczewski and Melanie S. Sanford
DOI: 10.1039/C4SC02591A
Open Access

The application of chiroptical spectroscopy (circular dichroism) in quantifying binding events in lanthanide directed synthesis of chiral luminescent self-assembly structures
Oxana Kotova, Salvador Blasco, Brendan Twamley, John O’Brien, Robert D. Peacock, Jonathan A. Kitchen, Miguel Martínez-Calvo and Thorfinnur Gunnlaugsson  
DOI: 10.1039/C4SC02474E
Open Access

ITQ-54: a multi-dimensional extra-large pore zeolite with 20 × 14 × 12-ring channels
Jiuxing Jiang, Yifeng Yun, Xiaodong Zou, Jose Luis Jorda and Avelino Corma 
DOI: 10.1039/C4SC02577F
Open Access

Polycyclic aromatic azomethine ylides: a unique entry to extended polycyclic heteroaromatics
Reinhard Berger, Manfred Wagner, Xinliang Feng and Klaus Müllen  
DOI: 10.1039/C4SC02793K
Open Access

Enantioselective α-amination enabled by a BINAM-derived phase-transfer catalyst
H. M. Nelson, J. S. Patel, H. P. Shunatona and F. D. Toste  
DOI: 10.1039/C4SC02494J
Open Access

“Self-repairing” nanoshell for cell protection
Nan Jiang, Xiao-Yu Yang, Guo-Liang Ying, Ling Shen, Jing Liu, Wei Geng, Ling-Jun Dai, Shao-Yin Liu, Jian Cao, Ge Tian, Tao-Lei Sun, Shi-Pu Li and Bao-Lian Su  
DOI: 10.1039/C4SC02638A
Open Access

Reversible photo-induced trap formation in mixed-halide hybrid perovskites for photovoltaics
Eric T. Hoke, Daniel J. Slotcavage, Emma R. Dohner, Andrea R. Bowring, Hemamala I. Karunadasa and Michael D. McGehee  
DOI: 10.1039/C4SC03141E
Open Access

Diaryldichalcogenide radical cations
Ole Mallow, Monther A. Khanfar, Moritz Malischewski, Pamela Finke, Malte Hesse, Enno Lork, Timo Augenstein, Frank Breher, Jeffrey R. Harmer, Nadezhda V. Vasilieva, Andrey Zibarev, Artem S. Bogomyakov, Konrad Seppelt and Jens Beckmann 
DOI: 10.1039/C4SC02964J
Open Access

Structural study of a small molecule receptor bound to dimethyllysine in lysozyme
Róise E. McGovern, Brendan D. Snarr, Joseph A. Lyons, James McFarlane, Amanda L. Whiting, Irina Paci, Fraser Hof and Peter B. Crowley   
DOI: 10.1039/C4SC02383H
Open Access

Ligand design for Rh(III)-catalyzed C–H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones
Todd K. Hyster, Derek M. Dalton and Tomislav Rovis 
DOI: 10.1039/C4SC02590C
Open Access

Annihilation electrogenerated chemiluminescence of mixed metal chelates in solution: modulating emission colour by manipulating the energetics
Emily Kerr, Egan H. Doeven, Gregory J. Barbante, Conor F. Hogan, David J. Bower, Paul S. Donnelly, Timothy U. Connell and Paul S. Francis 
DOI: 10.1039/C4SC02697G
Open Access

Selecting reactions and reactants using a switchable rotaxane organocatalyst with two different active sites
Jack Beswick, Victor Blanco, Guillaume De Bo, David A. Leigh, Urszula Lewandowska, Bartosz Lewandowski and Kenji Mishiro  
DOI: 10.1039/C4SC03279A
Open Access

Tailored chondroitin sulfate glycomimetics via a tunable multivalent scaffold for potentiating NGF/TrkA-induced neurogenesis
Pei Liu, Liwei Chen, Jerry K. C. Toh, Yi Li Ang, Joo-Eun Jee, Jaehong Lim, Su Seong Lee and Song-Gil Lee  
DOI: 10.1039/C4SC02410A
Open Access

Optical and electronic properties of air-stable organoboron compounds with strongly electron-accepting bis(fluoromesityl)boryl groups
Zuolun Zhang, Robert M. Edkins, Jörn Nitsch, Katharina Fucke, Andreas Steffen, Lauren E. Longobardi, Douglas W. Stephan, Christoph Lambert and Todd B. Marder 
DOI: 10.1039/C4SC02410A
Open Access

Ligand functionalization as a deactivation pathway in a fac-Ir(ppy)3-mediated radical addition
James J. Devery III, James J. Douglas, John D. Nguyen, Kevin P. Cole, Robert A. Flowers II and Corey R. J. Stephenson  
DOI: 10.1039/C4SC03064H
Open Access

In vivo visible light-triggered drug release from an implanted depot
Carl-Johan Carling, Mathieu L. Viger, Viet Anh Nguyen Huu, Arnold V. Garcia and Adah Almutairi   
DOI: 10.1039/C4SC02651A
Open Access

Non-equilibrium cobalt(III) “click” capsules
P. R. Symmers, M. J. Burke, D. P. August, P. I. T. Thomson, G. S. Nichol, M. R. Warren, C. J. Campbell and P. J. Lusby  
DOI: 10.1039/C4SC03036B
Open Access

Ultrafast infrared spectroscopy reveals water-mediated coherent dynamics in an enzyme active site
Katrin Adamczyk, Niall Simpson, Gregory M. Greetham, Andrea Gumiero, Martin A. Walsh, Michael Towrie, Anthony W. Parker and Neil T. Hunt  
DOI: 10.1039/C4SC02752C
Open Access

A counteranion triggered arylation strategy using diaryliodonium fluorides
L. Chan, A. McNally, Q. Y. Toh, A. Mendoza and M. J. Gaunt
DOI: 10.1039/C4SC02856B
Open Access

Transition-metal-free controlled polymerization for poly(p-aryleneethynylene)s
Takanobu Sanji, Asahi Motoshige, Hideaki Komiyama, Junko Kakinuma, Rie Ushikubo, Satoru Watanabe and Tomokazu Iyoda 
DOI: 10.1039/C4SC02872D
Open Access


Chemical Science is the Royal Society of Chemistry’s flagship journal, publishing research articles of exceptional significance and high-impact reviews from across the chemical sciences. It has been Gold Open Access since January 2015. The journal’s latest (2013) Impact Factor is 8.6. Research in Chemical Science is not only of the highest quality but also has excellent visibility: this is reflected in our latest citation profile.

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