HOT Chem Sci articles for June

Here are this month’s referee-recommended HOT Chem Sci articles– download them for FREE for a limited time!

Optimising in situ click chemistry: the screening and identification of biotin protein ligase inhibitors
Andrew D Abell, William Tieu, Tatina Soares da Costa, Min Yap, Kelly Keeling, Matthew C. J. Wilce, John Wallace, Grant Booker and Steven William Polyak
Chem. Sci., 2013, Accepted Manuscript
DOI: 10.1039/C3SC51127H, Edge Article

Free to access until 28th July 2013


One-shot indole-to-carbazole p-extension by Pd-Cu-Ag trimetallic system
Kyohei Ozaki, Hua Zhang, Hideto Ito, Aiwen Lei and Kenichiro Itami
Chem. Sci., 2013, Advance Article
DOI: 10.1039/C3SC51447A, Edge Article

Free to access until 28th July 2013


Oxygen activation by homoprotocatechuate 2,3-dioxygenase: a QM/MM study reveals the key intermediates in the activation cycle
Wenzhen Lai, Geng Dong and Sason Shaik
Chem. Sci., 2013, Accepted Manuscript
DOI: 10.1039/C3SC51147B, Edge Article

Free to access until 28th July 2013


Development of a generic activation mode:  nucleophilic a-substitution of ketones via oxy-allyl cations
David W. C. MacMillan, Mark Vanderwal and Andrew K Dilger
Chem. Sci., 2013, Accepted Manuscript
DOI: 10.1039/C3SC51266E, Edge Article

Free to access until 14th July 2013


5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
Richard J Hopkinson, Anthony Tumber, Clarence Yapp, Rasheduzzaman Chowdhury, WeiShen Aik, Ka Hing Che, Xuan Shirley Li, Jan B. L. Kristensen, Oliver King, Mun Chiang Chan, Kar Kheng Yeoh, Hwanho Choi, Louise J Walport, Cyrille C Thinnes, Jacob T Bush, Clarisse Lejeune, Anna M Rydzik, Nathan R Rose, Eleanor A L Bagg, Michael A McDonough, Tobias Krojer, Wyatt W Yue, Stanley S Ng, Lars Olsen, Paul Brennan, Udo Oppermann, Susanne Muller-Knapp, Robert J Klose, Peter J Ratcliffe, Christopher J Schofield and Akane Kawamura
Chem. Sci., 2013, Accepted Manuscript
DOI: 10.1039/C3SC51122G, Edge Article

Free to access until 14th July 2013


Enantioselective synthesis of hindered cyclic dialkyl ethers via catalytic oxa-Michael/Michael desymmetrization
Michael T. Corbett and Jeffrey S. Johnson
Chem. Sci., 2013, 4, 2828-2832
DOI: 10.1039/C3SC51022K, Edge Article

C3SC51022K

Free to access until 14th July 2013

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