Coinage metal (gold, silver, copper) complexes with a thiourea component have shown significant cytotoxicities towards cancer cells and, in particular, the gold(I) thiourea complex exhibits a potent tight-binding inhibition of the anticancer drug target thioredoxin reductase.
Chi-Ming Che and his colleagues at the University of Hong Kong and a collaborator at CNRS, in France, have published their findings in Chemical Communications – Why not read the article here, which is also free to access until the end of August.