O-Glycoligases: a new category of glycoside bond-forming mutant enzymes

A team of scientists from Canada and Korea have developed a mutant glycosidase enzyme that can catalyse the synthesis of an O-linked sugar called isoprimeveroside in near quantitative yield.

Stephen Withers, at the University of British Columbia, Canada, and colleagues report their findings in their ChemComm communication, which is part of the ChemCommEnzymes & Proteins’ web-based themed issue. The communication is free to access until 9th December 2010.

Graphical abstract: O-Glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)