Chemical Science Blog

This month sees the following articles in Chemical Science that are in the top ten most accessed:-

General palladium-catalyzed aerobic dehydrogenation to generate double bonds
Weiming Gao, Zhiqi He, Yong Qian, Jing Zhao and Yong Huang
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00661D

Direct aerobic a,ß-dehydrogenation of aldehydes and ketones with a Pd(TFA)2/4,5-diazafluorenone catalyst
Tianning Diao, Tyler J. Wadzinski and Shannon S. Stahl
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00724F

Catalytic enantioselective electrocyclic cascades
Eleanor E. Maciver, Peter C. Knipe, Andrew P. Cridland, Amber L. Thompson and Martin D. Smi
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00697E

Highly stereoselective catalytic conjugate addition of acyl anion equivalent to nitroolefins
Daisuke Uraguchi, Yusuke Ueki and Takashi Ooi
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00678A

Rollover’ cyclometalation – early history, recent developments, mechanistic insights and application aspects
Burkhard Butschke and Helmut Schwarz
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00651G

Bifunctional organo/metal cooperative catalysis with cinchona alkaloid scaffolds
Linus Stegbauer, Filippo Sladojevich and Darren J. Dixon
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00416F

Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction
Sundaram Rajkumar, Kenneth Shankland, Geoffrey D. Brown and Alexander J. A. Cobb
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00592H

Aggregation-induced emission in BF₂-hydrazone (BODIHY) complexes
Yin Yang, Xin Su, Calden N. Carroll and Ivan Aprahamian
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00658D

The first group 4 metal bis(imido) and tris(imido) complexes
Andrew D. Schwarz, Alastair J. Nielson, Nikolas Kaltsoyannis and Philip Mountford
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00786F

Copper-catalyzed direct oxidative synthesis of a-ketoamides from aryl methyl ketones, amines, and molecular oxygen
Feng-Tian Du and Jian-Xin Ji
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00312G

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Chemical Science that are in the top ten most accessed:-

Stereoselective piperidine synthesis through oxidative carbon–hydrogen bond functionalizations of enamides
Gediminas J. Brizgys, Hyung Hoon Jung and Paul E. Floreancig
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00670C

Amorphous molybdenum sulfide films as catalysts for electrochemical hydrogen production in water
Daniel Merki, Stéphane Fierro, Heron Vrubel and Xile Hu
Chem. Sci., 2011, 2, 1262-1267, DOI: 10.1039/C1SC00117E

ß-hydroxy ketones prepared by regioselective hydroacylation
Stephen K. Murphy, Matthew M. Coulter and Vy M. Dong
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00634G

N-heterocyclic carbene cascade catalysis: Dual Brønsted/Lewis base rearrangement of cyclopropyl enol esters to dihydropyranones
Lisa Candish and David W. Lupton
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00666E

Cooperative Lewis acid/N-heterocyclic carbene catalysis
Daniel T. Cohen and Karl A. Scheidt
Chem. Sci., 2012, 3, 53-57, DOI: 10.1039/C1SC00621E

Palladium(0)-catalyzed cyclopropane C–H bond functionalization: synthesis of quinoline and tetrahydroquinoline derivatives
Sophie Rousseaux, Benoît Liégault and Keith Fagnou
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00458A

C(sp3)–F reductive elimination from alkylgold(iii) fluoride complexes
Neal P. Mankad and F. Dean Toste
Chem. Sci., 2012, 3, 72-76, DOI: 10.1039/C1SC00515D

Copper-catalyzed direct oxidative synthesis of a-ketoamides from aryl methyl ketones, amines, and molecular oxygen
Feng-Tian Du and Jian-Xin Ji
Chem. Sci., 2012, Advance Article, DOI: 10.1039/C1SC00312G

Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles
Lutz Ackermann, Lianhui Wang and Alexander V. Lygin
Chem. Sci., 2012, 3, 177-180, DOI: 10.1039/C1SC00619C

A general approach to the enantioselective a-oxidation of aldehydes via synergistic catalysis
Scott P. Simonovich, Jeffrey F. Van Humbeck and David W. C. MacMillan
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00556A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Chemical Science? Then why not submit to us today or alternatively contact us with your suggestions.

This month sees the following articles in Chemical Science that are in the top ten most accessed:-

Why not take a look at the articles today and blog your thoughts and comments below.

A general approach to the enantioselective a-oxidation of aldehydes via synergistic catalysis
Scott P. Simonovich, Jeffrey F. Van Humbeck and David W. C. MacMillan
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00556A

A robust and scalable synthesis of the potent neuroprotective agent (-)-huperzine A
Maung Kyaw Moe Tun, Daniel-Joachim Wüstmann and Seth B. Herzon
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00455G

Palladium(0)-catalyzed cyclopropane C–H bond functionalization: synthesis of quinoline and tetrahydroquinoline derivatives
Sophie Rousseaux, Benoît Liégault and Keith Fagnou
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00458A

Asymmetric synthesis of highly functionalized cyclopentanes by a rhodium- and scandium-catalyzed five-step domino sequence
Brendan T. Parr, Zhanjie Li and Huw M. L. Davies
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00434D

Use of precatalysts greatly facilitate palladium-catalyzed alkynylations in batch and continuous-flow conditions
Wei Shu and Stephen L. Buchwald
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00409C

Asymmetric dearomatization of pyrroles via Ir-catalyzed allylic substitution reaction: enantioselective synthesis of spiro-2H-pyrroles
Chun-Xiang Zhuo, Wen-Bo Liu, Qing-Feng Wu and Shu-Li You
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00517K

Tracking gold acetylides in gold(i)-catalyzed cycloisomerization reactions of enynes
Antoine Simonneau, Florian Jaroschik, Denis Lesage, Magdalena Karanik, Régis Guillot, Max Malacria, Jean-Claude Tabet, Jean-Philippe Goddard, Louis Fensterbank, Vincent Gandon and Yves Gimbert
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00478F

Enantioselective rhodium-catalyzed arylation of electron-deficient alkenylarenes
Aakarsh Saxena and Hon Wai Lam
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00521A

Reactivity of NHC Au(i)–C s-bonds with electrophiles. An investigation of their possible involvement in catalytic C–C bond formation
Magnus T. Johnson, J. Marthinus Janse van Rensburg, Martin Axelsson, Mårten S. G. Ahlquist and Ola F. Wendt
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00428J

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective
Xile Hu
Chem. Sci., 2011, 2, 1867-1886, DOI: 10.1039/C1SC00368B

Fancy submitting an article to Chemical Science? Then why not submit to us today or alternatively contact us your suggestions.

This month sees the following articles in Chemical Science that are in the top ten most accessed:-

A robust and scalable synthesis of the potent neuroprotective agent (-)-huperzine A
Maung Kyaw Moe Tun, Daniel-Joachim Wüstmann and Seth B. Herzon
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00455G

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective
Xile Hu
Chem. Sci., 2011, 2, 1867-1886, DOI: 10.1039/C1SC00368B

Ruthenium-catalyzed intramolecular carbocyclization of alkynes with an sp3 carbon involving an oxidative deprotonation process
Bo-Xiao Tang, Ren-Jie Song, Cui-Yan Wu, Zhi-Qiang Wang, Yu Liu, Xiao-Cheng Huang, Ye-Xiang Xie and Jin-Heng Li
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00423A

Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefins
Miao Ding, Feng Zhou, Yun-Lin Liu, Cui-Hong Wang, Xiao-Li Zhao and Jian Zhou
Chem. Sci., 2011, 2, 2035-2039, DOI: 10.1039/C1SC00390A

The effect of the N-mesityl group in NHC-catalyzed reactions
Jessada Mahatthananchai and Jeffrey W. Bode
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00397F

Divergent reactions of indoles with aminobenzaldehydes: indole ring-opening vs. annulation and facile synthesis of neocryptolepine
Matthew K. Vecchione, Aaron X. Sun and Daniel Seidel
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00506E

Template-directed synthesis of p-conjugated porphyrin [2]rotaxanes and a [4]catenane based on a six-porphyrin nanoring
Matthew J. Langton, Jonathan D. Matichak, Amber L. Thompson and Harry L. Anderson
Chem. Sci., 2011, 2, 1897-1901, DOI: 10.1039/C1SC00358E

Synthesis of natural-product-like scaffolds in unprecedented efficiency via a 12-fold branching pathway
Diane Robbins, Annabella F. Newton, Camille Gignoux, Jean-Christophe Legeay, Alex Sinclair, Martin Rejzek, Carly A. Laxon, Sai K. Yalamanchili, William Lewis, Maria A. O’Connell and Robert A. Stockman
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00371B

Photocatalytic reductive cyclizations of enones: Divergent reactivity of photogenerated radical and radical anion intermediates
Juana Du, Laura Ruiz Espelt, Ilia A. Guzei and Tehshik P. Yoon
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00357G

Enantioselective carbon–sulfur bond formation: y additions of aryl thiols to allenoates catalyzed by a chiral phosphepine
Yuji Fujiwara, Jianwei Sun and Gregory C. Fu
Chem. Sci., 2011, Advance Article, DOI: 10.1039/C1SC00414J

Why not take a look at the articles today and blog your thoughts and comments below.

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