August 2025 – Chemical Science Blog

Archive for August, 2025

Yi-Tao Long selects his Editor’s Choice in analytical chemistry and sensors

19 Aug 2025

Professor Yi-Tao Long, Nanjing University

Professor Yi-Tao Long’s Editor’s Choice

We are delighted to share with you our latest Editor’s Choice collection that presents a selection of notable research contributions in analytical chemistry and sensors in Chemical Science from 2023 to 2024.

The featured articles selected by Chemical Science Associate Editor, Yi-Tao, demonstrate 18 cutting-edge papers in analytical chemistry and sensors, highlighting innovations in imaging, diagnostics, phototherapy, mass spectroscopy, AI-powered detection and more.

From photodynamic therapy to high-throughput proteomics, these studies showcase key advances in analytical chemistry and the creativity and interdisciplinary strength of chemical research published in Chemical Science.

Professor Long considers work at the forefront of analytical chemistry, including significant advances in spectroscopic analysis and electrochemistry. Submit your best manuscripts on these topics to Chemical Science for Professor Long’s consideration.

We hope you enjoy reading this selection of articles chosen by Professor Yi-Tao Long.

A mitochondria-localized iridium(III) photosensitizer for two-photon photodynamic immunotherapy against melanoma Lili Wang, Johannes Karges, Fangmian Wei, Lina Xie, Zhuoli Chen, Gilles Gasser, Liangnian Ji and Hui Chao Chem. Sci., 2023, 14, 1461-1471
Rational design of mesoporous chiral MOFs as reactive pockets in nanochannels for enzyme-free identification of monosaccharide enantiomers Junli Guo, Xuao Liu, Junjian Zhao, Huijie Xu, Zhida Gao, Zeng-Qiang Wu and Yan-Yan Song Chem. Sci., 2023, 14, 1742-1751
Ligand engineering of Au₄₄ nanoclusters for NIR-II luminescent and photoacoustic imaging-guided cancer photothermal therapy Ge Yang, Xueluer Mu, Xinxin Pan, Ying Tang, Qiaofeng Yao, Yaru Wang, Fuyi Jiang, Fanglin Du, Jianping Xie, Xianfeng Zhou and Xun Yuan Chem. Sci., 2023, 14, 4308-4318
Acceptor engineering of metallacycles with high phototoxicity indices for safe and effective photodynamic therapy Chonglu Li, Le Tu, Jingfang Yang, Chang Liu, Yuling Xu, Junrong Li, Wei Tuo, Bogdan Olenyuk, Yan Sun, Peter J. Stang and Yao Sun Chem. Sci., 2023, 14, 2901-2909
Target-mediated self-assembly of DNA networks for sensitive detection and intracellular imaging of APE1 in living cells Xue-Mei Zhou, Ying Zhuo, Ruo Yuan and Ya-Qin Chai Chem. Sci., 2023, 14, 2318-2324
The compact integration of a cascaded HCR circuit for highly reliable cancer cell discrimination Pei Dong, Ruomeng Li, Shizhen He, Qingqing Zhang, Jinhua Shang, Yuqian Jiang, Xiaoqing Liu and Fuan Wang Chem. Sci., 2023, 14, 2159-2167
Automatic materials characterization from infrared spectra using convolutional neural networks Guwon Jung, Son Gyo Jung and Jacqueline M. Cole Chem. Sci., 2023, 14, 3600-3609
Oxidization enhances type I ROS generation of AIE-active zwitterionic photosensitizers for photodynamic killing of drug-resistant bacteria Jianye Gong, Lingxiu Liu, Chunbin Li, Yumao He, Jia Yu, Ying Zhang, Lina Feng, Guoyu Jiang, Jianguo Wang and Ben Zhong Tang Chem. Sci., 2023, 14, 4863-4871
All-in-One digital microfluidics pipeline for proteomic sample preparation and analysis Jiaxi Peng, Calvin Chan, Shuailong Zhang, Alexandros A. Sklavounos, Maxwell E. Olson, Erica Y. Scott, Yechen Hu, Vigneshwar Rajesh, Bingyu B. Li, M. Dean Chamberlain, Shen Zhang, Hui Peng and Aaron R. Wheeler Chem. Sci., 2023, 14, 2887-2900
Selective FRET nano probe based on carbon dots and naphthalimide–isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao and Tony D. James Chem. Sci., 2024, 15, 757-764
Lanthanide MOF-based luminescent sensor arrays for the detection of castration-resistant prostate cancer curing drugs and biomarkers Xinrui Wang, Karuppasamy Gopalsamy, Gilles Clavier, Guillaume Maurin, Bin Ding, Antoine Tissot and Christian Serre Chem. Sci., 2024, 15, 6488-6499
Redox-mediated electrochemiluminescence enhancement for bead-based immunoassay Alessandro Fracassa, Claudio Ignazio Santo, Emily Kerr, Sara Knežević, David J. Hayne, Paul S. Francis, Frederic Kanoufi, Neso Sojic, Francesco Paolucci and Giovanni Valenti Chem. Sci., 2024, 15, 1150-1158
Ratiometric near-infrared fluorescent probe for nitroreductase activity enables 3D imaging of hypoxic cells within intact tumor spheroids Janeala J. Morsby, Zhumin Zhang, Alice Burchett, Meenal Datta and Bradley D. Smith Chem. Sci., 2024, 15, 3633-3639
Dynamic surface reconstruction of individual gold nanoclusters by using a co-reactant enables color-tunable electrochemiluminescence Yan-Mei Lei, Di Wu, Mei-Chen Pan, Xiu-Li Tao, Wei-Jia Zeng, Li-Yong Gan, Ya-Qin Chai, Ruo Yuan and Ying Zhuo Chem. Sci., 2024, 15, 3255-3261
High-throughput single-cell mass spectrometry enables metabolic network analysis by resolving phospholipid CC isomers Simin Cheng, Chenxi Cao, Yao Qian, Huan Yao, Xiaoyun Gong, Xinhua Dai, Zheng Ouyang and Xiaoxiao Ma Chem. Sci., 2024, 15, 6314-6320
High-throughput drug target discovery using a fully automated proteomics sample preparation platform Qiong Wu, Jiangnan Zheng, Xintong Sui, Changying Fu, Xiaozhen Cui, Bin Liao, Hongchao Ji, Yang Luo, An He, Xue Lu, Xinyue Xue, Chris Soon Heng Tan and Ruijun Tian Chem. Sci., 2024, 15, 2833-2847
A simplified and efficient extracellular vesicle-based proteomics strategy for early diagnosis of colorectal cancer Jin Zhang, Zhaoya Gao, Weidi Xiao, Ningxin Jin, Jiaming Zeng, Fengzhang Wang, Xiaowei Jin, Liguang Dong, Jian Lin, Jin Gu and Chu Wang Chem. Sci., 2024, 15, 18419-18430
Calibration-free reaction yield quantification by HPLC with a machine-learning model of extinction coefficients Matthew A. McDonald, Brent A. Koscher, Richard B. Canty and Klavs F. Jensen Chem. Sci., 2024, 15, 10092-10100

If you are interested in research in similar areas, explore our most popular 2024 analytical chemistry articles collection and our related Imaging, biosensing and diagnostics: 2025 Chemical Science symposium collection.

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