Archive for March, 2011

Who’s who in Chemical Science

We have 17 world-leading Associate Editors working with Editor-in-Chief David MacMillan to ensure that Chemical Science represents the new thinking from across the chemical sciences. But can you match the faces with the names? Number 1, David MacMillan, is N – but what about the others?

Post your answers below – all correct answers will be in with the chance of winning a prize …

1. David MacMillan, Princeton University, USA
Editor-in-Chief
2. Chris Bielawski, University of Texas, Austin
Associate Editor: Polymer Science
3. Stephen L Buchwald, MIT, USA
Associate Editor: Organic Chemistry
4. Thomas Carell, Ludwig-Maximilians-Universität München, Germany
Associate Editor: Chemical Biology and Bioorganic Chemistry
5. Benjamin F Cravatt, Scripps, USA
Associate Editor: Chemical Biology
6. Christopher C Cummins, MIT, USA
Associate Editor: Inorganic and Organometallic Chemistry
7. Kazunari Domen, University of Tokyo, Japan
Associate Editor: Physical Chemistry, Energy and Surface Science
8. Matthew Gaunt, University of Cambridge, UK
Associate Editor: Organic Chemistry
9. Hubert Girault, Ecole Polytechnique Fédérale de Lausanne, Switzerland
Associate Editor: Analytical Science
10. David A Leigh, University of Edinburgh, UK
Associate Editor: Supramolecular Chemistry
11. Kopin Liu, Academia Sinica, Taiwan
Associate Editor: Physical Chemistry
12. Jeffrey R Long, UC Berkeley, USA
Associate Editor: Inorganic Chemistry
13. Wonwoo Nam, Ewha Womans University, Korea
Associate Editor: Bioinorganic Chemistry
14. Colin Nuckolls, Columbia University, USA
Associate Editor: Organic Materials
15. Teri Odom, Northwestern University, USA
Associate Editor: Nanoscience
16. Matthew J Rosseinsky, University of Liverpool, UK
Associate Editor: Inorganic Materials
17. F Dean Toste UC Berkeley, USA
Associate Editor: Organic Chemistry
18. Haw Yang, Princeton University, USA
Associate Editor: Physical Chemistry

Five prize-winners will be selected at random from winning entrants who have supplied a valid email address with their correct entry. Competition closes at 24.00 GMT on 30th April 2011. Winners will be notified by email.

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Probing Alzheimer’s disease with transition metals

amyloid fibrils

Group 9 metal complexes can inhibit amyloid aggregation, thought to be responsible for neurodegeneration in Alzheimer’s disease patients.

Dik-Lung Ma (University of Hong Kong) and colleagues made iridium(III) and rhodium(III) complexes that can both inhibit the aggregation of Ab1-40 peptides and acts as luminescent probes for the peptides. Their iridium complex is the first example of a transition metal complex that displays a ‘switch-on’ luminescence response upon binding to Ab1-40 peptides; the magnitude of response can be used to distinguish between the peptide’s monomeric and fibrillar forms.

Read the full Edge Article for free in Chemical Science.

Submit your exceptional research today to be seen with the best.

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Do catalytic reactions take place inside MOF pores?

Scientists have made a large-pored metal-organic framework (MOF) that they say provides a conclusive answer to a long standing issue: do catalytic reactions take place inside the pores?

Chiral MOFs are of great interest for enantioselective catalysis but they have had limited success as enantioselective catalysis in terms of catalytic turnover and stereoselectivity, partly due to their lack of void space. There are a number of reports of chiral MOFs with pores large enough to accommodate whole molecules. It has been assumed that the reactions occur both at the surface and also in the pores but until now the evidence has been circumstantial, according to Nakcheol Jeong at Korea University in Seoul.

Jeong’s MOF has organic linkers that maintain local chirality with functional groups that can be modified on demand to produce new catalysts. He used the MOF catalyst for a carbonyl-ene reaction and says he has conclusively proved that the reaction occurs entirely inside the pores.

You can read Jeong’s Edge article for free in Chemical Science.  Let us know if you agree with the conclusions by leaving your comments below.

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