Editors’ collection: Elegant Synthetic Routes to Indole Derivatives

RSC Advances are delighted to share our latest collection on Elegant Synthetic Routes to Indole Derivatives, guest edited by Dr. Sarbani Pal (MNR Degree and PG College, India) and Associate Editor Prof. Manojit Pal (Dr Reddy’s Institute of Life Sciences, India).

Indoles are attractive targets in organic synthesis because of not only their widespread existences in nature especially in alkaloids but also their importance as privileged structures in Medicinal / Pharmaceutical Chemistry and Drug Discovery. It is not surprising that the indole framework is a commonly found N-heteroarene moiety in many bioactive agents and drugs. Additionally, many indoles served as key precursors to a range of valuable compounds that find applications in various areas of science. Thus, enormous efforts have been devoted for the development of elegant synthetic routes to various indole derivatives or indole based complex structures. This current web collection is mainly a compilation of relevant important and interesting research papers already published in RSC Advances during last 7 years. The major focus of this compilation was on selection of the elegant synthetic methods including single or multi-step approaches, multi-component reactions, transition or other metal catalysed methods, cascade reactions, environmentally friendly approaches etc reported for indole derivatives. The reports on simple or mere derivatization / functionalization of indole ring are generally excluded. Some selected papers reporting synthesis as well as biological activities of indole derivatives are also included.

RSC Advances is most cited gold open access journal dedicated to the chemical sciences and all publications in our journal are free to access. We hope you enjoy reading these articles

Featured articles:

TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline
Manda Sathish, Akash P. Sakla, Fabiane M. Nachtigall, Leonardo S. Santos and Nagula Shankaraiah
RSC Adv., 2021,11, 16537-16546

Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
Qijing Zhang, Qianrong Li and Chengming Wang
RSC Adv., 2021,11, 13030-13033

l-Isoleucine derived bifunctional phosphine catalyses asymmetric [3 + 2]-annulation of allenyl-esters and -ketones with ketimines
Muthukumar G. Sankar, Miguel Garcia-Castro, Christopher Golz, Carsten Strohmann and Kamal Kumar
RSC Adv., 2016,6, 56537-56543

Read the full collection

If you would like to submit your research to this collection, and give your work the global visibility it deserves, you can do so now!

All submissions will be subject to an initial assessment by Associate Editors and, if suitable for the journal, they will be subject to rigorous peer review to meet the usual high standards of RSC Advances.

Submit your research

Meet the Editors

Dr. Sarbani Pal (nee Das) is a faculty and Head of the Chemistry Department, MNR Degree and Post-Graduate College, Hyderabad, India. After receiving PhD degree from Jadavpur University, Kolkata (India) in 1996, she joined the Department of Chemistry, M.S. University, Baroda, Gujarat (India) where she worked as a Lecturer in Chemistry (1996–1997). Subsequently, she moved to Hyderabad (India), where she joined the MNR College (affiliated to Osmania University, Hyderabad) and continuing since then. Her research interests include the total synthesis of bicyclic and tricyclic sesquiterpenes, synthesis of organo-ruthenium complexes, click reactions, design and synthesis of anti-inflammatory agents and macrolide antibiotics etc. She has supervised several PhD students, authored / co-authored a book and a book chapter along with more than 60 research papers and 5 review articles in various international journals. She is a recipient of Bioorganic and Medicinal Chemistry Letters Top 10 Cited Author award for 2011–2012, certificate for being outstanding reviewer for RSC Advances in 2017, Publons peer review awards 2017, certificate for top cited article 2020-2021 from Wiley etc. Her review article on macrolides and ketolides was recognized as a “top-50 most downloaded” article from Tetrahedron on ScienceDirect 2006. She is currently a member of board of Management of MNR University, Hyderabad, India.

 

Prof. Manojit Pal received his PhD degree from Jadavpur University, Kolkata (India) in 1995 under the guidance of Prof. Nitya G. Kundu and then worked in various industrial R & D centres including Alembic, Sun Pharma, Matrix Lab, and Dr Reddy’s Lab Ltd. In 2009, he joined the Dr. Reddy’s Institute of Life Science, Hyderabad and presently continuing as a Senior Professor of Organic and Medicinal Chemistry as well as Chief Scientist of CIMPS Department. He became Associate Editor of RSC Advances in 2015, FRSC in 2016, Adjunct Faculty-Manipal University in 2018 and member of Editorial Board-Bioorganic Chemistry in 2019. He also became invited member of ACS in 2019. His name is featured in Stanford’s list of top 2% scientists in the world 2020. In 2022, he received a certificate for publishing open access articles with Elsevier some of which were linked to the United Nations Sustainable Development Goals. His research interests include the development of new chemical entities under the new drug discovery programme in various therapeutic areas namely tuberculosis, inflammation, obesity, psoriasis and cancer. The other major areas of his focus include transition metal / non-metal catalysed reactions, sonochemical approaches, green chemistry, heterocycle synthesis etc. He has authored/co-authored more than 280 research publications, as well as 18 review articles, a number of patents, a book chapter and a book. So far he has reviewed more than 1200 manuscripts, a number of PhD thesis from both national and international universities and grant proposals at national and international level.

About RSC Advances

RSC Advances Royal Society of Chemistry

We are here for everyone who wants to publish quality chemistry research and share it with the world. Published by the Royal Society of Chemistry and led by active researchers, we publish work in all areas of chemistry and our low article processing charges, discounts and waivers make publishing open access achievable and sustainable. Learn more.

 

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RSC Advances Welcomes Stephen Ojwach as a New Associate Editor

The RSC Advances team are delighted to welcome Professor Stephen Ojwach as our newest Associate Editor!

Professor Stephen Ojwach, University of KwaZulu-Natal, South Africa

Research Areas: organometallic chemistry, homogeneous catalysis, coordination chemistry, ligand design, transition metal chemistry, and green chemistry.

Prof Ojwach obtained his PhD in Organometallic Chemistry and Homogeneous Catalysis from the University of Johannesburg, South Africa under the supervision of Professor James Darkwa. Currently a professor of Inorganic Chemistry at the University of KwaZulu-Natal, South Africa, he is also a visiting professor at a number of institutions: the University of Lethbridge, Canada, RWTH Aachen University and Technical University of Kaiserslautern, Germany, and University of Strasbourg, France, among others.

Prof Ojwach has made exemplary contribution to the design and development of transition metal complexes as catalysts for various organic transformations, including, but not limited to, oligomerization, polymerization, carbonylation, and hydrogenation reactions. His research involves careful manipulation of ligand design to optimize the catalytic properties (Structure-Property-Activity-Relationship, SPAR) of complexes in given transformation. Kinetics, mechanistic and theoretical studies are undertaken to offer insights for rationale future catalyst designs.

Prof Ojwach has published over 100 research articles in the fields of inorganic chemistry, organometallic chemistry, and catalysis in a broad scope of journals such as RSC Advances, Dalton Transactions, Organometallics, Molecular Catalysis, and Inorganic Chemistry.

Check out Prof Ojwach’s latest RSC publications!

Structural and ethylene oligomerization studies of chelating (imino)phenol Fe(ii), Co(ii) and Ni(ii) complexes: an experimental and theoretical approach
Makhosonke Ngcobo, Holliness Nose, Arumugam Jayamani and Stephen O. Ojwach
New J. Chem., 2022,46, 6219-6229

Carboxamide carbonyl-ruthenium(II) complexes: detailed structural and mechanistic studies in the transfer hydrogenation of ketones
Robert T. Kumah, Paranthaman Vijayan and Stephen O. Ojwach
New J. Chem., 2022,46, 3146-3155

Role of π-conjugation on the coordination behaviour, substitution kinetics, DNA/BSA interactions, and in vitro cytotoxicity of carboxamide palladium(II) complexes
Reinner O. Omondi, Nicole R. S. Sibuyi, Adewale O. Fadaka, Mervin Meyer, Deogratius Jaganyi and Stephen O. Ojwach.
Dalton Trans., 2021,50, 8127-8143

Prof Ojwach is looking forward to receiving your papers! Submit to RSC Advances today. Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest Popular Advances, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

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Call for papers: Nanoarchitectonics Advances: Bridge over Nanotechnology and Materials Science

 

RSC Advances is delighted to announce a new themed collection titled ‘Nanoarchitectonics Advances: Bridge over Nanotechnology and Materials Science’. This collection is Guest Edited by Katsuhiko Ariga (National Institute for Materials Science & The University of Tokyo, Japan), Hiromitsu Maeda (Ritsumeikan University, Japan), Stéphane Baudron (Université de Strasbourg-CNRS, France), and Yulan Chen (Jilin University, China).

Scope

Expanding and going beyond the field of nanotechnology, a new concept of nanoarchitectonics has been proposed. Nanoarchitectonics aims to construct materials with precise structures that achieve high performance from nanoscale units such as atoms, molecules, and nanomaterials. Beyond the well-known strategies of self-assembly and related strategies, nanoarchitectonics aims to construct material structures containing more asymmetric and hierarchical motifs from multiple components. Nanoarchitectonics bridges the missing link between nanotechnology and materials science. The impact of nanoarchitectonics goes beyond fabricating such structures to developing nanostructured materials useful for sensing, catalysis, energy, environmental, and biomedical applications.

Such attempts have in fact been widely studied but should be reconstructed under the name of nanoarchitectonics as a link between nanotechnology and materials science. This special issue will encompass the development of various functions enabled by this bottom-up approach to structure development. Examples of possible targets include:

1) Supramolecular assemblies and self-assemblies

2) Coordination nanostructures such as MOFs

3) Hybrids, composites, and blends that exhibit nanostructures and functions

4) Various other functional materials that include nanostructures

5) Sensing, catalytic, energy, environmental, biomedical and other applications

This special issue should not only describe conventional approaches, but also how the research relates to nanoarchitectonics.

Please make sure that your submission provides an insight that advances the chemistry field or is of interest to the chemistry community.

How to submit

Both Papers and Review articles will be considered for this issue. All submissions will be subject to an initial assessment by Associate Editors and, if suitable for the journal, they will be subject to rigorous peer review to meet the usual high standards of RSC Advances.

Our APC is among the lowest in the industry and there are no submission charges. Discounts and waivers are offered to authors from developing countries.

If you would like to submit to this issue the manuscript should be prepared according to our article guidelines and submitted via our online system anytime before the submission deadline of 30 July 2023. During submission, authors will be asked if they are submitting for a themed collection and should include the name of the themed collection. If you would like to submit but require additional time to prepare your article, please do let us know by contacting the journal.

RSC Advances Royal Society of ChemistrySubmit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest Popular Advances, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

 

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SACI-44 Poster Prize and Flash Presentation Winners

The 44th South African Chemical Institute’s National Convention took place between 8 – 13 January 2023. Over the course of these 5 days, the conference was home to plenary and parallel sessions covering all areas of chemistry, though the overarching theme was chemistry for sustainable development in Africa. The event was part of the International Year of Basic Sciences for Sustainable Development – SA IYBSSD 2022.

RSC Advances, along with Dalton Transactions, were pleased to sponsor six poster prize winners and four flash presentation winners. We are delighted that the conference was such a success and we would like to wish a huge congratulations to all of the winners!

Poster prize winners:

• PA5 Geyan Kempkes, University of Pretoria
Development of a novel graphene-based passive air sampler for mercury monitoring

• PI5 Taryn Golding, University of Cape Town
Ferrocenyl aminoquinoline-benzimidazole molecular hybrids as antiplasmodial agents

• PA43 Derrick Sipoyo, University of Venda
Synthesis of naphthalene derivatives as bifunctional electrolyte additives for lithium-ion batteries

• PP14 Kgalaletso Otukile, University of the Free State
First-principles based evaluation of rate constants for R + O2 reactions with R = ethyl, isopropyl, isobutyl, t-butyl and neopentyl

• PO30 Trégen Snayer, Stellenbosch University
Studies towards resolving racemic C4-symmetric inherently chiral calix[4]arenes

• PI33 Shira Zinman, University of Cape Town
Expanding the versatility of aminoquinoline organometallic complexes as anticancer and antibacterial agents

Peter Mallon (SACI previous president), Geyan Kempkes, Trégen Snayer, and Catharine Esterhuysen (Chair of 44th SACI National Convention)

Flash presentation winners:

• PO27 Ursula Ralepelle, University of Limpopo
Reduction of alkynyl carbonyl compounds using SnCl2 and computational investigation of the reaction mechanism

• PO37 Sarah Wright, University of the Witwatersrand
Phenylcyclobutenone annulation reactions as new entry towards total syntheses of aglycones gilvocarcins

• PP8 Mofeli Leoma, Rhodes University
Better insights into the squalene monooxygenase inhibitors for lowering cholesterol in cardiovascular biology using molecular docking and molecular dynamics simulations

• PI12 Luccile Mbonzhe, University of Venda
A Zinc-based 3D mixed ligand metal-organic-framework with stepwise CO2 adsorption at low temperature

Peter Mallon, Ursula Ralepelle, Sarah Wright, Mofeli Leoma, and Catharine Esterhuysen 

Find out more about the Pan Africa Chemistry Network, which seeks to create a self-sustaining science base in Africa, helping to build capacity, solve local challenges and contribute to global knowledge.

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December 2022 RSC Advances Review Articles

Welcome to December’s Review round up!

Every month we update our 2022 Reviews in RSC Advances collection to showcase all of the review articles published in RSC Advances in 2022. Don’t forget to come back next month to check out our latest reviews.

We hope you enjoy reading and as always, all of our articles are open access so you can easily share your favourites online and with your colleagues.

Explore the full collection!

Browse a selection of our December reviews below:

Natural products as antivibrio agents: insight into the chemistry and biological activity
Noer Kasanah, Maria Ulfah and David C. Rowley
RSC Adv., 2022, 12, 34531-34547

Recent development of biodegradable synthetic rubbers and bio-based rubbers using sustainable materials from biological sources
Zhen Hern Boon, Yin Yin Teo and Desmond Teck-Chye Ang
RSC Adv., 2022, 12, 34028-34052

Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions
Diana Hurtado-Rodríguez, Angélica Salinas-Torres, Hugo Rojas, Diana Becerra and Juan-Carlos Castillo
RSC Adv., 2022, 12, 35158-35176

Optimization mechanism and applications of ultrafast laser machining towards highly designable 3D micro/nano structuring
Xiaomeng Yang, Ruiqi Song, Liang He, Leixin Wu, Xin He,a Xiaoyu Liu, Hui Tang, Xiaolong Lu, Zeyu Ma and Peng Tian
RSC Adv., 2022, 12, 35227-35241

Antiviral role of nanomaterials: a material scientist’s perspective
Muhammad Aanish Ali, Nagina Rehman, Tae Joo Park and Muhammad Abdul Basit
RSC Adv., 2023, 13, 47-79

Submit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest Popular Advances, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

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December 2022 Popular Advances Articles

Welcome to December’s Popular Advances article round up!

Every month we update our 2022 RSC Advances Popular Advances Article Collection to showcase all of the articles selected by our reviewers and handling editors as Popular Advances in 2022. Don’t forget to come back next month to check out our latest Popular articles.

We hope you enjoy reading and as always, all of our articles are open access so you can easily share your favourites online and with your colleagues.

Explore the full collection!

 

Microwave-assisted synthesis, molecular docking studies of 1,2,3-triazole-based carbazole derivatives as antimicrobial, antioxidant and anticancer agents
Dongamanti Ashok, Gugulothu Thara, Bhukya Kiran Kumar, Gundu Srinivas, Dharavath Ravinder, Thumma Vishnu, Madderla Sarasija and Bujji Sushmitha
RSC Adv., 2023, 13, 25-40

Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies
Asmat Ullah, Atia-tul-Wahab, Peng Gong, Abdul Mateen Khan and M. Iqbal Choudhary
RSC Adv., 2023, 13, 355-369
 

Submit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest  Popular Advances articles, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

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Call for papers: Advances in Sustainable Hydrogen Energy Systems

RSC Advances is delighted to announce a new themed collection titled ‘Advances in sustainable hydrogen energy systems’. This collection is Guest Edited by Nader Karimi (Queen Mary University of London, UK), Manosh C. Paul (University of Glasgow, UK), Larry K. B. Li (The Hong Kong University of Science and Technology, Hong Kong), Mohammad Hossein Doranehgard (University of Alberta, Canada), and Freshteh Sotoudeh (Houston University, USA).

Scope

It is now clear that developing low-carbon economy is an essential prerequisite to sustainability. Despite the great desire for the replacement of fossil fuels with hydrogen, realisation of hydrogen economy continues to be a grand challenge. Currently, there exists a wide range of technologies for the production, storage and utilisation of hydrogen. Nevertheless, hydrogen-based integrated energy systems that are economically viable and environmentally friendly have not been developed yet.

This themed collection has been motivated the new wave of research on the design, analysis, and assessment of future hydrogen energy systems. Thermodynamic, technoeconomic and environmental analyses are central to such efforts to complement elements of socioeconomics and policy making.

The purpose of this collection is to bring together the latest research findings of the international, multidisciplinary community of hydrogen energy on the system-level analyses of hydrogen technologies. In particular, contributions are sought in the following fields:

  • Energy, exergy, economic, and environmental analysis of hydrogen systems.
  • Technoeconomic, exergoeconomic and exergoenvironmental investigations of hydrogen production, storage and utilisation.
  • Applications of machine learning and data-centric techniques to the analysis of hydrogen energy systems.
  • Multi-objective optimisation of hydrogen energy systems using conventional and emerging techniques.
  • Integration and hybridisation of hydrogen energy systems with other sustainable energy systems.

Please make sure that your submission provides an insight that advances the chemistry field or is of interest to the chemistry community.

How to submit

Both Papers and Review articles will be considered for this issue. All submissions will be subject to an initial assessment by Associate Editors and, if suitable for the journal, they will be subject to rigorous peer review to meet the usual high standards of RSC Advances.

Our APC is among the lowest in the industry and there are no submission charges. Discounts and waivers are offered to authors from developing countries.

If you would like to submit to this issue the manuscript should be prepared according to our article guidelines and submitted via our online system anytime before the submission deadline of 30 June 2023. During submission, authors will be asked if they are submitting for a themed collection and should include the name of the themed collection. If you would like to submit but require additional time to prepare your article, please do let us know by contacting the journal.

RSC Advances Royal Society of ChemistrySubmit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest Popular Advances, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

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November 2022 RSC Advances Review Articles

Welcome to November’s Review round up!

Every month we update our 2022 Reviews in RSC Advances collection to showcase all of the review articles published in RSC Advances in 2022. Don’t forget to come back next month to check out our latest reviews.

We hope you enjoy reading and as always, all of our articles are open access so you can easily share your favourites online and with your colleagues.

Explore the full collection!

Browse a selection of our November reviews below:

ZIF-8 metal organic framework materials as a superb platform for the removal and photocatalytic degradation of organic pollutants: a review
Aicha Elaouni, M. El Ouardi, M. Zbair, A. BaQais, M. Saadi and H. Ait Ahsaine
RSC Adv., 2022, 12, 31801-31817

Radiolabelling small and biomolecules for tracking and monitoring
Martin R. Edelmann
RSC Adv., 2022, 12, 32383-32400

Self-healable fiber-reinforced vitrimer composites: overview and future prospects
Harsh Sharma, Sravendra Rana, Poonam Singh, Mikihiro Hayashi, Wolfgang H. Binder, Elisabeth Rossegger, Ajay Kumar and Sandra Schlögl
RSC Adv., 2022, 12, 32569-32582

Copper oxide nanostructured thin films processed by SILAR for optoelectronic applications
Md Abdul Majed Patwary, Md Alauddin Hossain, Bijoy Chandra Ghos, Joy Chakrabarty, Syed Ragibul Haque, Sharmin Akther Rupa, Jamal Uddin and Tooru Tanaka
RSC Adv., 2022, 12, 32853-32884

Ammonia from dinitrogen at ambient conditions by organometallic catalysts
Debashree Bora, Firdaus Rahaman Gayen and Biswajit Saha
RSC Adv., 2022, 12, 33567-33583

The role of polyplexes in developing a green sustainable approach in agriculture
Pratyush K. Das, Gyanendra Panda, Kananbala Patra, Nivedita Jena and Mamoni Dash
RSC Adv., 2022, 12, 34463-34481

 

Submit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest Popular Advances, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

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November 2022 Popular Advances Articles

Welcome to November’s Popular Advances article round up!

Every month we update our 2022 RSC Advances Popular Advances Article Collection to showcase all of the articles selected by our reviewers and handling editors as Popular Advances in 2022. Don’t forget to come back next month to check out our latest Popular articles.

We hope you enjoy reading and as always, all of our articles are open access so you can easily share your favourites online and with your colleagues.

Explore the full collection!

Highly sensitive detection of polyborosiloxane (PBS) hydrolysis with mannitol using electrochemical methodology
Baoliang Liu, Xiaoyang Zhang, Qikun Zhang, Yucheng Sun and Zaijun Lu
RSC Adv., 2022, 12, 31168-31172

Revealing the anisotropic phonon behaviours of layered SnS by angle/temperature-dependent Raman spectroscopy
Xiangnan Gong, Ting Yan, Jue Li, Jie Liu, Hanjun Zou, Bin Zhang, Hong Wu, Zizhen Zhou and Xiaoyuan Zhou
RSC Adv., 2022, 12, 32262-32269

Evaluation of antiviral activity of Carica papaya leaves against SARS-CoV-2 assisted by metabolomic profiling
Amr Adel, Mohamed S. Elnaggar, Amgad Albohy, Ahmed A. Elrashedy, Ahmed Mostafa, Omnia Kutkat, Usama Ramadan Abdelmohsen, Eman Al-Sayed and Mohamed A. Rabeh
RSC Adv., 2022, 12, 32844-32852

Mesoporous acidic polymeric ionic liquids as novel solid acids for catalytic hydrolysis of ketoxime reactions
Shanshan Zhao, Zhengxiang Ma, Peng Cheng, Yanji Wang, Xinqiang Zhao, Qiusheng Yang, Junqi Zhang and Dongsheng Zhang
RSC Adv., 2022, 12, 33276-33283

 

Submit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

Keep up to date with our latest  Popular Advances articles, Reviews, Collections & more by following us on Twitter. You can also keep informed by signing up to our E-Alerts.

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RSC Advances Science Communications: Potential use of exopolysaccharides

The group of Dr. Lin Zhou have a research interest in Schizophyllan (SPG). As a biological macromolecule polysaccharide, SPG demonstrates good biological activity such as anti-tumor, anti-aging, antioxidant and moisturizing etc. The large molecular weight and high viscosity of SPG can also affect the level of dissolved oxygen in the later stage of fermentation, which limits the yield of SPG. In addition, separation and purification of SPG is time and cost intensive. The traditional herbal medicine contains great health value. Therefore, researchers have focused on the overall activity of the fermentation broth to expand the application of S. commune liquid fermentation.

In the article “Enhanced exopolysaccharide yield and antioxidant activities of Schizophyllum commune fermented products by the addition of Radix Puerariae, the medicinal edible fungus Schizophyllum commune (S. commune) was used as the starting strain, and the traditional Chinese medicine Radix Puerariae (RP) was used as the medicinal substrate to expand the application of the S. commune fermentation liquids. The results showed that the addition of Pueraria did not affect the structure of Schizophyllan (SPG), the exopolysaccharide of S. commune, but the yield of SPG was significantly improved, which provided a theoretical basis for the industrial production of SPG. In addition, RP can also increase the antioxidant activity of the fermented supernatant from the S. commune fermentation system. These antioxidant activities mainly come from the puerarin from RP and some new ingredients that are synthesized during the fermentation process such as resveratrol. Therefore, this study proves the feasibility of the Schizophyllum liquid fermentation system as a bioreactor and provides a reference for the biotransformation of edible medicinal fungi such as Cordyceps militaris and Ganoderma lucidum etc.

Resumen gráfico: Mayor rendimiento de exopolisacáridos y actividades antioxidantes de los productos fermentados de Schizophyllum commune mediante la adición de Radix Puerariae

Firstly, this research confirmed the feasibility of using the liquid fermentation of Schizophyllum commune as a biotransformer, and provided a reference for the expanded application of Schizophyllum commune and other medicinal and edible fungi. The results also shed light on the comprehensive utilization of traditional herbal medicine and plant substrates.

For the bidirectional fermentation system, monitoring of the fermentation process and evaluation of the biological activity of the fermentation products are the hotspots of future research. Follow up work about the anti-aging activity and underlying mechanisms of fermented S. commune by a Caenorhabditis elegans model will be reported in the near future. 

I thank Dr. Lin Zhou for his cordial responses.

 

Read the article:

Enhanced exopolysaccharide yield and antioxidant activities of Schizophyllum commune fermented products by the addition of Radix Puerariae. Yongfei Deng, Qian Huang, Lu Hu, Tao Liu, Bisheng Zheng, Dengjun Lu, Chaowan Guo and Lin Zhou. RSC Adv., 2021, 11, 38219–38234.

 

About the web writer:

 

Cristian M. O. Lépori is a Doctor in Chemical Sciences and is currently a CONICET researcher at the Universidad Nacional de Río Cuarto, Argentina. His research area is “Comprehensive approach through the articulation of knowledge and new strategies for the development of innovative products and processes applicable to health and the environment”. He likes to plan, organize and carry out science dissemination activities. You can find him on Twitter at @cristianlepo.

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