Poly(ethylene glycol) is one of the most frequently used polymers for biomedical applications.
In this review, recent developments in controlled polymerisation techniques – and particularly those they allow alternatives to PEG – are highlighted. Key to the biological application of these techniques is a method by which to improve the properties of polymer therapeutics and several are presented in this review. However, a more comprehensive understanding of the complex interactions of synthetic materials with the numerous biological entities and barriers in the human body is necessary in order fine-tune their therapeutic impact.
Interested to know more? Why not read the full article for free: M. Barz, R. Luxenhofer, R. Zentel and M. J. Vicent, Polym. Chem., 2011, DOI: 10.1039/c0py00406e (Advance Article)