Covalently linked protein–nanogel hybrids (PNHs) have been synthesized using AGET ATRP in an inverse miniemulsion.
A genetically engineered protein, which contained a non-natural amino acid bearing an ATRP initiator, has been used to synthesise protein–nanogel hybrids by electron transfer ATRP in an inverse miniemulsion. This is an appropriate synthetic strategy to covalently, site specifically incorporate green fluorescent proteins into well-defined nanogels. The hybrids are expected to be suitable for potential controlled release applications.
Interested to know more? Why not read the full article for free: S. E. Averick, A. J. D. Magenau, A. Simakova, B. F. Woodman, A. Seong, R. A. Mehl and K. Matyjaszewski, Polym. Chem., 2011, DOI: 10.1039/c1py00050k (Advance Article)
