PDMS-based microfluidic devices are commonly used for aqueous based applications; however, their limited chemical resistance and high swelling in many common organic solvents make them unfeasible for uses involving organic solvents or harsh conditions. Here the authors report a new perfluoropolyether-based material, which has liquid-like viscosity and can be cured into a tough, highly durable elastomer. The highly fluorinated elastomer possesses remarkable resistance to a variety of organic solvents, water, heat and even harsh acidic and basic conditions.
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