Author Archive

Shanti Swarup Bhatnagar Prize for Chemical Sciences awarded

Professor Pradyut Ghosh, IACS, India

The Shanti Swarup Bhatnagar Prize for chemical sciences is awarded annually by the Council of Scientific and Industrial Research (CSIR) to two Indian scientists, recognizing outstanding research in the applied and fundamental chemical sciences. This year, one of the winners of this prestigious award was Professor Pradyut Ghosh (Indian Association for the Cultivation of Science, Kolkata), who received the prize for his notable work in the fields of inorganic and supramolecular chemistry. A frequent contributor to ChemComm, Professor Ghosh’s work spans many key areas including anion recognition chemistry, molecular encapsulation, chemical sensing of ions, extraction of inorganic salts and supramolecular aggregates. To celebrate Professor Ghosh’s remarkable achievements, we are delighted to present a collection of his recent ChemComm articles below.


In relation to the broad themes of Professor Ghosh’s work, we would like to highlight the upcoming ISACS18: Challenges in Organic Materials and Supramolecular Chemistry conference which will be held in India for the very first time on 19-21 November 2015 in Bangalore. On behalf of the ISACS18 Chair and ChemComm Associate Editor Professor S Ramakrishnan (Indian Institute of Science) and Dr May Copsey (Executive Editor), we warmly invite you to come to this historic and significant event, which will also be attended by our India representatives, Dr Aparna Ganguly and Dr Deeksha Gupta.

Read Professor Ghosh’s latest ChemComm articles below:

Artificial receptors for nitrate: a comprehensive overview
Ranjan Dutta and Pradyut Ghosh
Chem. Commun., 2015, 51, 9070-9084
DOI: 10.1039/C5CC01266J, Feature Article

Selective recognition and extraction of KBr via cooperative interactions with a urea functionalized crown ether dual-host
Bidyut Akhuli and Pradyut Ghosh
Chem. Commun., 2015, Advance Article
DOI: 10.1039/C5CC07291C, Communication

Halogen bonding assisted selective removal of bromide
Sourav Chakraborty, Ranjan Dutta and Pradyut Ghosh
Chem. Commun., 2015, 51, 14793-14796
DOI: 10.1039/C5CC05495H, Communication

Recent developments in anion induced capsular self-assemblies
Ranjan Dutta and Pradyut Ghosh
Chem. Commun., 2014, 50, 10538-10554
DOI: 10.1039/C4CC02957G, Feature Article

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In celebration of the 2015 Nobel Prize in Chemistry

The 2015 Nobel Prize in Chemistry was jointly awarded to  Tomas Lindahl, former director of Cancer Research UK’s Clare Hall Laboratories, Paul Modrich from Duke University in the US and Aziz Sancar from the University of North Carolina in the US  for their  “mechanistic studies of DNA repair”.

nobel laureates
Tomas Lindahl, Paul Modrich and Aziz Sancar © Inserm-P. Latron, Mary Schwalm/AP/Press Association, Max Englund/UNC School of Medicine.

Tomas Lindahl’s research pieced together a molecular image of how base excision repairs DNA when a base of a nucleotide is damaged and subsequently managed to recreate the human repair process in vitro. The mechanism known as nucleotide excision repair, which excises damage from UV and carcinogenic substances, was then mapped by Aziz Sancar – the molecular details of this process changed the entire research field. Paul Modrich also studied the human version of the repair system. His work focused on DNA mismatch repair, a natural process which corrects mismatches that occur when DNA is copied during cell division.

The research carried out by the three 2015 Nobel Laureates in Chemistry has not only revolutionised our knowledge of how we function but also lead to the development of life – saving treatments. To celebrate these remarkable achievements, we are delighted to present a collection of recent Chemical Communications, Chemical Science and Chemical Society Reviews articles on DNA repair, FREE to read until 1 December 2015!

We invite you to submit your best research related to DNA repair mechanisms to Chemical Communications, Chemical Science and Chemical Society Reviews!


Finding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules
Anton Granzhan, Naoko Kotera and  Marie-Paule Teulade-Fichou
Chem. Soc. Rev., 2014, 43, 3630-3665
DOI: 10.1039/C3CS60455

The chemical biology of sirtuins
Bing Chen, Wenwen Zang, Juan Wang, Yajun Huang, Yanhua He,  Lingling Yan,  Jiajia Liu and Weiping Zheng
Chem. Soc. Rev., 2015, 44, 5246-5264
DOI: 10.1039/C4CS00373J

Luminescent oligonucleotide-based detection of enzymes involved with DNA repair
Chung-Hang Leung, Hai-Jing Zhong, Hong-Zhang He, Lihua Lu, Daniel Shiu-Hin Chan and Dik-Lung Ma
Chem. Sci., 2013, 4, 3781-3795
DOI: 10.1039/C3SC51228B



Research articles

A label-free and sensitive fluorescent method for the detection of uracil-DNA glycosylase activity
Jing Tao, Panshu Song, Yusuke Sato, Seiichi Nishizawa, Norio Teramae, Aijun Tong  and Yu Xiang
Chem. Commun., 2015, 51, 929-932
DOI: 10.1039/C4CC06170E

DNA-mediated supercharged fluorescent protein/graphene oxide interaction for label-free fluorescence assay of base excision repair enzyme activity
Zhen Wang, Yong Li, Lijun Li, Daiqi Li, Yan Huang, Zhou Nie and Shouzhuo Yao
Chem. Commun., 2015, 51, 13373-13376
DOI: 10.1039/C5CC04759E

A fluorescent G-quadruplex probe for the assay of base excision repair enzyme activity
Chang Yeol Lee, Ki Soo Park and Hyun Gyu Park
Chem. Commun., 2015, 51, 13744-13747
DOI: 10.1039/C5CC05010C

A chemical probe targets DNA 5-formylcytosine sites and inhibits TDG excision, polymerases bypass, and gene expression
Liang Xu, Ying-Chu Chen, Satoshi Nakajima, Jenny Chong, Lanfeng Wang,  Li Lan, Chao Zhang and  Dong Wang
Chem. Sci., 2014, 5, 567-574
DOI: 10.1039/C3SC51849C

Sensitive detection of polynucleotide kinase using rolling circle amplification-induced chemiluminescence
Wei Tang, Guichi Zhu and Chun-yang Zhang
Chem. Commun., 2014, 50, 4733-4735
DOI: 10.1039/C4CC00256C

Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase
Alhosna Benjdia, Korbinian Heil, Andreas Winkler, Thomas Carell and Ilme Schlichting
Chem. Commun., 2014, 50, 14201-14204
DOI: 10.1039/C4CC05158K

Expanding DNAzyme functionality through enzyme cascades with applications in single nucleotide repair and tunable DNA-directedassembly of nanomaterials
Yu Xiang, Zidong Wang, Hang Xing and  Yi Lu
Chem. Sci., 2013, 4, 398-404
DOI: 10.1039/C2SC20763J

Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe
Ka-Ho Leung, Hong-Zhang He, Victor Pui-Yan Ma, Hai-Jing Zhong, Daniel Shiu-Hin Chan,  Jun Zhou,  Jean-Louis Mergny, Chung-Hang Leung and  Dik-Lung Ma
Chem. Commun., 2013, 49, 5630-5632
DOI: 10.1039/C3CC41129J

Endonuclease IV discriminates mismatches next to the apurinic/apyrimidinic site in DNA strands: constructing DNA sensing platforms with extremely high selectivity
Xianjin Xiao, Yang Liu and  Meiping Zhao
Chem. Commun., 2013, 49, 2819-2821
DOI: 10.1039/C3CC40902C

Also of interest: Find out more about the three Chemistry Nobel Laureates and their research.

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