Chemical Communications Blog

Chemists mask amines’ unwanted reactivity with carbon dioxide and overcome limitations of amide formation

Chemists at Imperial College London, UK, have overcome limitations that afflict a specific class of amidation reactions, used to produce a range of compounds from drugs to valuable materials. Their simple trick was to add carbon dioxide, which masks the reagent’s reactivity, making sure it only reacts when they want it to.

Read the full article in Chemistry World >>>