Alkyne insertion imparts silicon stereochemistry

Jenny Lovell writes about a hot ChemComm article for Chemistry World

Scientists in Japan have reported a way of inserting alkynes into carbon–silicon bonds, also known as alkynylsilylation, that creates silicon stereogenic centres with high enantioselectivity.

The literature is littered with examples of alkyne insertion into carbon–silicon bonds to synthesise alkenylsilanes but until now, there has been limited progress in synthesising their alkynyl cousins. Now, Ryo Shintani and Kyoko Nozaki at the University of Tokyo have developed a successful rhodium-catalysed intramolecular method to achieve this. Read the full article in Chemistry World»

Read the original journal article in ChemComm:
Rhodium-catalyzed intramolecular alkynylsilylation of alkynes
Ryo Shintani, Hiroki Kurata and Kyoko Nozaki
Chem. Commun., 2015,51, 11378-11381
DOI: 10.1039/C5CC04172D, Communication

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