Scientists in Japan have made a new DNA delivery substrate based on networks of bio-friendly upright silica sheets. The network of sheets forms a porous film on to which they can immobilise DNA, ready for delivery (transfection) into cells. The transfection efficiency of the silica film is approximately double that of solution-based transfection. Gene transfection is a potential method for preventing and treating diseases and analysing cell functions.
Link to journal article
Silica-based Gene Reverse Transfection: Upright Nanosheet Network for Promoted DNA Delivery to Cell
Q Ji et al
Chem. Commun., 2012, DOI: 10.1039/c2cc34289h
