Personal glucose sensors (PGS) can be used to detect cancer, say Chinese scientists.
The team loaded magnetic beads with invertase (an enzyme that catalyses the hydrolysis of sucrose to glucose) and an antibody. The beads acted as a label for a lung cancer biomarker that had been captured on an antibody-coated ELISA plate. By monitoring the production of glucose from sucrose with a PGS, they could indirectly measure the amount of the biomarker down to the sub-nanogram per millilitre level.
Link to journal article
Personal glucose sensor for point-of-care early cancer diagnosis
Jiao Su, Jin Xu, Ying Chen, Yun Xiang, Ruo Yuan and Yaqin Cha
Chem. Commun., 2012, Accepted Manuscript, DOI: 10.1039/C2CC32729E
