Sleeping Trojan horse to transport metal ions into cancer cells

Waking up to new possibilities in imaging

UK researchers have used a cage-like molecule to smuggle metal ions into cells, which could improve medical imaging.

Medical imaging often requires getting unnatural materials such as metal ions into cells. Scientists have therefore had to come up with ways to disguise these compounds to get them past the cell membranes. Michael Coogan and colleagues at Cardiff University have come up with a way to avoid the current difficulties with some of these imaging treatments.

Graphical abstract: A ‘Sleeping Trojan Horse’ which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging

Find out their solution by reading the news story in Chemistry World and downloading Coogan’s ChemComm communication.

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