RSC Advances Blog

RSC Advances is delighted to announce a new themed collection on CRISPR-Based Diagnostics Methods, Devices, and Applications. 

This collection is Guest Edited by Dr Zhen Rong (Beijing Institute of Microbiology and Epidemiology, China), Prof Wataru Nomura (Hiroshima University, Japan) and Prof Weihua Guan (Pennsylvania State University, USA).

Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-based diagnostics have been widely applied to sensitive and accurate nucleic acid analysis based on its highly efficient trans-cleavage activity. CRISPR assays can be integrated with nucleic acid amplification testing methods, microfluidic devices, and novel biosensors to simplify operation workflow and improve analytical performance, thus making it more applicable at point-of-care needs. Current challenges focus on the development of single-step nucleic acid amplification cascade CRISPR assays, “sample-in, answer-out” devices, and multiplex CRISPR assays.

This themed collection focuses on the development and applications of novel CRISPR-based diagnostics methods and devices. Potential topics include, but are not limited to:

1. CRISPR-based diagnostics methods: nucleic acid amplification cascade CRISPR assays, amplification-free CRISPR assays, and digital CRISPR assays.
2. CRISPR-based diagnostics devices: CRISPR-integrated microfluidic devices, paper-based analytical devices, field-effect transistors, surface plasmon resonance biosensors, and other novel analytical devices.
3. CRISPR-based diagnostics applications: point-of-care detection of emerging pathogens, molecular diagnosis of genetic diseases, genotyping of variants, and discrimination of drug resistance mutations.
4. Chemistry-oriented CRISPR research for analytical and diagnostic applications.

This collection welcomes primary research articles as well as review articles in related fields to contribute to our special issue. To be suitable for consideration, RSC Advances submissions should provide insight that advances the chemistry field.

We welcome your submission to the collection!

The deadline for manuscript submission is 21^st September 2024. 

Please note our data requirements and guidelines here. If your manuscript contains electrophoresis data, please be aware we require images of the full, raw, and uncropped images.

All manuscripts will be subject to the journal’s usual peer review process. Accepted manuscripts will be published in a regular issue of the journal as soon as possible and then added to the themed collection on the journal webpage.

RSC Advances’ article processing charge (APC) is among the lowest in chemistry and waivers are also available for authors who meet the eligibility criteria outlined here. We have a number of Read & Publish deals in place with institutions, please see Chronoshub for more information on specific institutions and funders.

If you would like to submit to this themed collection the manuscript should be prepared according to our article guidelines and submitted via our online system any time before the submission deadline of 21st September 2024. During submission, authors will be asked if they are submitting for a themed collection and should include the name of the themed collection. If you would like to submit but require additional time to prepare your article, please do let us know by contacting the journal.

Submit to RSC Advances today! Check out our author guidelines for information on our article types or find out more about the advantages of publishing in a Royal Society of Chemistry journal.

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