RSC Advances Blog

The shock wave device does not need to touch the mouse to trigger the drug release

Scientists in India have developed a shock wave-based drug delivery system that could be used to administer insulin in diabetic patients and reduce the need for painful injections. A similar strategy could also increase the efficacy of antibiotic treatment to diabetic wounds.

In recent years, stimuli responsive drug delivery systems have come to the fore. Such systems enable greater control over where and when drugs are released in the body, ultimately providing more localised and sustained treatment with better overall results. Systems that are responsive to external stimuli such as ultrasound, infrared light and magnetic fields have all been reported, but often require specialist equipment that can be expensive to buy or difficult to operate, and this has limited their application in real clinical situations.

To read the full article please visit Chemistry World.

Remotely triggered micro-shock wave responsive drug delivery system for resolving diabetic wound infection and controlling blood sugar levels
Divya Prakash Gnanadhas, Monalisha Elango, Midhun Ben Thomas, Jagadeesh Gopalan and Dipshikha Chakravortty  
RSC Adv., 2015,5, 13234-13238
DOI: 10.1039/C4RA15270K, Paper

Supercapacitors are used in memory backup systems and portable electronics as well as high-power devices © Shutterstock

Researchers in the UK have designed a simple and inexpensive circuit that can linearise the charge–discharge behaviour of a capacitor. This could solve one of the most important problems plaguing the development of supercapacitors – the need for a straightforward measurement method for the amount of electrical charge they can store at a given voltage, known as capacitance. 

The circuit, reported by the group of Craig Banks at Manchester Metropolitan University, can be added to researchers’ existing cyclic voltammetry, electrochemical impedance spectroscopy and galvanostatic charge–discharge setups. It requires only two precise resistors and a variable capacitor of similar capacitance to the supercapacitor under investigation, components which cost as little as £5.

To read the full article visit Chemistry World.

A new approach for the improved interpretation of capacitance measurements for materials utilised in energy storage
Dimitrios K. Kampouris, Xiaobo Ji, Edward P. Randviir and Craig E. Banks  
RSC Adv., 2015,5, 12782-12791
DOI: 10.1039/C4RA17132B, Paper

Researchers in Brazil have created floating blocks that could be added to stagnant water to suppress the transmission of dengue fever.

The floating bricks support an iron oxide catalyst

Over 40% of the world’s population is thought to be at risk from dengue, according to World Health Organization estimates. It is spread through the bite of the Aedes aegypti mosquito and symptoms include high fever, joint pain and vomiting.

To read the full article please visit Chemistry World.

A photocatalytic process for the eradication of dengue through ˙OH generation in the presence of sunlight and iron oxide
G. V. Pereira, V. A. Freitas, H. S. Oliveira, L. C. A. Oliveira and  J. C. Belchior 
RSC Adv., 2014,4, 63650-63654
DOI: 10.1039/C4RA13435D

A methyl cellulose–carrageenan foam

Long-life foams that can act as oceanic mirrors are being explored by scientists in the UK. These reflective foams could one day ease global warming by managing incoming solar radiation. 

Planetary albedo is the proportion of sunlight reflected by Earth’s surface; two main areas contribute – land and ocean. Oceanic albedo is primarily caused by naturally occurring bubbles or foams produced by surface waves called whitecaps. They create an oceanic mirror but without them, ocean reflectance is only around 5%. Whitecaps, however, are short-lived, urging research into persistent foams that boost albedo.  

To read the full article visit Chemistry World.

Long-term stabilization of reflective foams in sea water
Alex Aziz, Helen C. Hailes, John M. Ward and Julian R. G. Evans  
RSC Adv., 2014,4, 53028-53036
DOI: 10.1039/C4RA08714C

Water droplets form spherical shapes on the composite’s surface

Scientists in China have made a mechanically stable superhydrophobic material from waste silicone.

Posted on behalf of Sarah Brown, web writer for RSC Advances

‘Waste not, want not’ my mother dearest would say, a strong proponent of cling-film and pourer of scorn on sell-by dates.  She would be delighted to read that scientists have been able to produce potential scaffolds for bone grafts from beer production waste.

The waste contains phosphorous, silicon, magnesium and calcium – the main components of bone – making it an ideal candidate to develop treatments, coatings, grafts and implants for osteo-based trauma.

Osteoblasts grown on a 3D biomaterial matrix

Reporting their work in RSC Advances, M. Angeles Martin-Luengo and co-workers investigated the residues from three different beer production plants in Spain to determine whether their origin would affect their suitability as biomaterial precursors.

The authors performed in vitro cell proliferation assays in the presence of the beer waste materials of different plants and found no discernable difference between the different wastes. No cytotoxicity was observed either, encouraging further investigations into their use in bone tissue engineering.

One of the major advantages of using beer production waste is the reduced cost in producing these medical aids compared with conventional materials. While commercial materials currently sell at $150 per gram, beer production waste costs around $40 per ton.

In short, these potential biomaterials are environmentally and economically friendly – I’ll drink to that! 

Interested in finding out more? Read the full article using the link below:

Preparation, characterization and in vitro osteoblast growth of waste-derived biomaterials 
M. Angeles Martin-Luengo and co-workers
RSC Adv.,2014, 4, 12630-12639

Sarah Brown is a guest web-writer for RSC Advances. Sarah hung up her lab coat after finishing her PhD and post-doctorate in nanotechnology for diagnostics and therapeutics and now works in academic publishing. When not trying to explain science through ridiculous analogies, you can often find her crocheting, baking or climbing, but not all at once.

Researchers from China have accidently discovered a super strong, super stretchy hydrogel, which has the potential to be used in tissue engineering.

Originally developed in the 1950s when Otto Wichterle and Drahoslav Lim invented soft contact lenses, supramolecular hydrogels are gel-like polymers that can absorb water. Akin to natural soft tissue, their networks are held together by reversible non-covalent interactions making them attractive materials for biomedical applications.

Hydrogels have good elasticity, but their mechanical weakness lets them down. Now, a new, stronger hydrogel with ‘amazing molecular properties’ has been created by Mingyu Guo and He Huang at Soochow University. The group were making water-dispersible polyurethane adhesives and noticed that strong stretchable gels formed when the samples were left in the air for a couple of days.

Interested? If so, read the full article at Chemistry World here

Written by Rachel Purser-Lowman for Chemistry World

With energy demands rising and the increasing importance of low-carbon technologies, scientists in Canada are investigating the microbial conversion of coal into methane, to find a way that coal, especially low grade unmineable coal, can be used, whilst minimising its environmental impact.

Methane, the primary constituent of natural gas, releases significantly less carbon dioxide, when burned, than coal. Biological generation of methane in a coal seam results from microbial activity that starts during the early stages of coal formation.

Increased pressure and heat eventually destroys the microbes, but secondary methane production can occur when meteoric water infiltrates the cooled coal, bringing new microbes and nutrients.

Interested? If so, read the full article at Chemistry World here!