Poly(N-vinyl pyrrolidone) has been an important ingredient for medicine, pharmacy and cosmetics due to its excellent wetting and film forming properties. N-vinyl pyrrolidone (NVP) can be readily polymerized by free radical polymerization; however, it has been a challenge to polymerize this monomer by controlled radical polymerization techniques.
Destarac and his co-workers have demonstrated controlled RAFT/MADIX polymerization of NVP in water and at room temperature. Moreover, they have presented the preparation of poly(acrylamide)-b-(N-vinyl pyrrolidone) for the first time.
Aqueous RAFT/MADIX polymerisation of N-vinyl pyrrolidone at ambient temperature by Aymeric Guinaudeau, Stéphane Mazières, D. James Wilson and Mathias Destarac Polym. Chem. 2011, 3, 81-84.