Diabetes currently affects over 347 million people worldwide and with this number set to rise, research into the treatment of this disease is of vital importance. For type 1 and advanced type 2 diabetes, patients must regularly prick their fingers to check their blood glucose levels and inject themselves with insulin accordingly. This not only impinges on a patient’s quality of life, but also fails to precisely control the dose of insulin reaching its main site of action, the liver.
![Glucose-responsive-nanogel-from-bean-plants_c3py00778b-ga_630](https://blogs.rsc.org/py/files/2013/08/Glucose-responsive-nanogel-from-bean-plants_c3py00778b-ga_630.jpg)
Glucose induces a conformation change in concanavlin A, causing a change in the volume of the nanogel
Interested to know more? Read the full news article by Jessica Cocker in Chemistry World here…
Read the article by T Ye et al. in Polymer Chemistry:
Synthesis and volume phase transition of concanavalin A-based glucose-responsive nanogels
Ting Ye, Suting Yan, Yumei Hu, Li Ding and Weitai Wu
DOI: 10.1039/C3PY00778B