Thiol-yne chemistry is an efficient mechanism to synthesize A2B star polymers. In the latest Polymer Chemistry Hot Article, Daniel Savin and co-workers at University of Southern Mississippi, USA, report the synthesis and solution characterization of polypeptide-based stars that serve as lipid mimetic molecules.
Using the thiol–yne convergent synthesis, the team envision a modular approach to functionalize proteins or oligopeptides with lipophilic chains that can imbed seamlessly into a cell membrane.
Fancy knowing more? Why not read the full article for free here:
