Scientists in Spain have devised a versatile technique that uses DNA to pull apart host–guest complexes so they can measure the overall strength of hydrogen bonds in that system. The method can distinguish forces as low as 0.1–1pN.
Procedures to measure supramolecular interactions in the bulk, under equilibrium conditions, are well established. But nature operates out of equilibrium, so scientists want a technique to measure hydrogen bonds in conditions realistic to living systems.
Read the full story by Jennifer Newton on Chemistry World.