Hot Article: Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

Poly(ethylene glycol) is one of the most frequently used polymers for biomedical applications.

In this review, recent developments in controlled polymerisation techniques – and particularly those they allow alternatives to PEG – are highlighted. Key to the biological application of these techniques is a method by which to improve the properties of polymer therapeutics and several are presented in this review. However, a more comprehensive understanding of the complex interactions of synthetic materials with the numerous biological entities and barriers in the human body is necessary in order fine-tune their therapeutic impact.

Interested to know more? Why not read the full article for free: M. Barz, R. Luxenhofer, R. Zentel and M. J. Vicent, Polym. Chem., 2011, DOI: 10.1039/c0py00406e (Advance Article)

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