Author Archive

Carbohydrates promoted in new prebiotic theory

It’s plausible that carbohydrates formed on primordial Earth before amino acids. So say UK researchers who have shown that parent molecules to amino acids can catalyse the formation of 2-deoxy-D-ribose, a sugar found in the backbone of DNA.1

Source: Royal Society of Chemistry Amino nitriles can promote the enantioselective aldol reaction of formaldehyde and glycolaldehyde to yield D-glyceraldehyde, and the subsequent reaction of the D-glyceraldehyde with acetaldehyde to make 2-deoxy-D-ribose

We’ll never know the exact process that turned chemistry into biology, but many researchers want to get as close as they can to the truth. Paul Clarke at the University of York is one of those researchers.

Read the full story by Jennifer Newton on Chemistry World.

1 A M Steer et al, Chem. Commun., 2017, DOI: 10.1039/c7cc06083a (This paper is open access.)

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Let single crystals do the heavy lifting

Researchers in the US have developed heat responsive crystalline cantilevers that are capable of lifting a metal ball almost 100 times heavier than the crystal itself.

Stimuli responsive behaviour in soft materials has blossomed in recent years, but for highly crystalline solids, such properties are still surprising, especially for materials that don’t lose their single crystalline nature in the process.

Source: Royal Society of Chemistry
Upon heating, the crystal lattice changes from herringbone packing to infinite 1D chains stacked co-facially along their π surfaces.

Jeremiah Gassensmith and colleagues at the University of Texas at Dallas and the University of North Texas, US, have developed single crystals of an N-substituted naphthalene diimide (NDI) derived organic semiconductor that can undergo a reversible phase change from its α to its β form under heating.

Read the full story by Jason Woolford on Chemistry World.

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HOT ChemComm articles for August

All of the referee-recommended articles below are free to access until 6th October 2017.

Photoactivatable aggregation-induced emission of triphenylmethanol
Yue Zheng, Xiaokun Zheng, Yu Xianga and Aijun Tong
Chem.Commun., 2017, Advance Article
DOI: 10.1039/C7CC04693F, Communication

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Orthogonal switching of self-sorting processes in a stimuli-responsive library of cucurbit[8]uril complexes
Stefan Schoder and Christoph A. Schalley
Chem. Commun., 2017, 53, 9546-9549
DOI: 10.1039/C7CC05469F, Communication

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Condensing the information in DNA with double-headed nucleotides 
Mick Hornum, Pawan K. Sharma, Charlotte Reslow-Jacobsen, Pawan Kumar, Michael Petersena and Poul Nielsen
Chem. Commun., 2017,53, 9717-9720
DOI: 10.1039/C7CC05047J, Communication

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High magnetic relaxivity in a fluorescent CdSe/CdS/ZnS quantum dot functionalized with MRI contrast molecules 
S. G. McAdams, D. J. Lewis, P. D. McNaughter, E. A. Lewis, S. J. Haigh, P. O’Brien and F. Tuna
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC05537D, Communication
This article is part of the themed collection: Commemorating Michael Faraday (1791-1867)

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What [plasma used for growing] diamond can shine like flame?
Michael N. R. Ashfold, Edward J. D. Mahoney, Sohail Mushtaq, Benjamin S. Truscotta and Yuri A. Mankelevich
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC05568D, Feature Article
This article is part of the themed collection: Commemorating Michael Faraday (1791-1867)

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Reversible structural switching of a metal-organic framework by photoirradiation
Varvara I. Nikolayenko, Simon A. Herberta and Leonard J. Barbour
Chem. Commun., 2017, Advance Article
10.1039/C7CC06074B, Communication

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2nd From Carbon-Rich Molecules to Carbon-Based Materials Conference

The 2nd From Carbon-Rich Molecules to Carbon-Based Materials Conference is to be held 7th – 10th June in Nassau, Bahamas.

This interdisciplinary conference will provide unique “fusion” opportunities for chemists, physicists and engineers having various backgrounds but sharing passion and interests in carbon-only or carbon-rich molecules and carbon-based materials. It will allow a diverse group of scientists from all over the globe to discuss the current challenges, needs and prospects of this quickly-evolving multidisciplinary field.

Dates for your diary

Early Bird- 7th December 2017

Talk Submission- 14th December 2017

Last Chance – 13th April 2018

You can click here to register now and see here for further information about the conference.

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Fluorescent test strip detects deadly phosgene gas

Chinese scientists have improved the sensitivity of test strips for phosgene gas by using a different fluorophore.

Phosgene gas reacts with lung proteins, disrupting the blood–air barrier and suffocating victims. Although deadly, many chemical plants require phosgene to synthesise products such as pharmaceuticals and pesticides. But accidental leaks are a risk. In 2016, for example, a leak at Gujarat Narmada Valley Fertilizers and Chemicals in India killed four workers and affected nine others.

Source: Royal Society of Chemistry
This is the first test-strip sensing system for gaseous phosgene made with AIE-based fluorophores

 

Read the full story by Sarah Piggott on Chemistry World.

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Automated synthesis yields sugar high

An automated synthetic method designed by chemists in Germany has assembled the longest synthetic oligosaccharide ever made from monosaccharides. The method could help to up the pace of carbohydrate research by improving researchers’ access to synthetic glycans.

Source: © Royal Society of Chemistry The researchers used automated glycan assembly to make a 50mer polymannoside

Read the full article by Jennifer Newton on Chemistry World.

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HOT ChemComm articles for July

All of the referee-recommended articles below are free to access until 10th September 2017.

Lewis acid catalyzed diastereoselective [3+4]-annulation of donor–acceptor cyclopropanes with anthranils: synthesis of tetrahydro-1-benzazepine derivatives
Zhe-Hao Wang, Huan-Huan Zhang, Dao-Ming Wang, Peng-Fei Xua and Yong-Chun Luo
Chem. Commun., 2017, 53, 8521-8524
DOI: 10.1039/C7CC04239F, Communication

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A Non-Enzyme Cascade Amplification Strategy for Colorimetric Assay of Disease Biomarkers
Jiuxing Li, Zhuangqiang Gao, Haihang Ye, Shulin Wan, Meghan Pierce, Dianping Tangb and Xiaohu Xia
Chem. Commun., 2017,53, 9055-9058
DOI: 10.1039/C7CC04521B, Communication

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Radiofluorination of a NHC-PF5 adduct: Toward new probes for 18F PET imaging
Boris Vabre, Kantapat Chansaenpak, Mengzhe Wang, Hui Wang, Zibo Li and François P. Gabbai
Chem. Commun., 2017,53, 8657-8659
DOI:  10.1039/C7CC04402J, Communication

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New mechanistic insights into intramolecular aromatic ligand hydroxylation and benzyl alcohol oxidation initiated by the well-defined (μ-peroxo)diiron(III) complex
Mio Sekino, Hideki Furutachi, Rina Tojo, Ayumi Hishi, Hanako Kajikawa, Takatoshi Suzuki, Kaito Suzuki, Shuhei Fujinami, Shigehisa Akine, Yoko Sakata, Takehiro Ohta, Shinya Hayamic and Masatatsu Suzukid
Chem. Commun., 2017,53, 8838-8841
DOI: 10.1039/C7CC04382A, Communication

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Activation of P-H Bond by a Frustrated Lewis Pair and its Application in Catalytic Z-selective Hydrophosphonylation of Terminal Ynones
Yizhen Liu, Xiaoting Fan, Zhen Hua Li and Huadong Wang
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC05028C, Communication

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Lone pair-π interaction-induced generation of photochromic coordination networks with photoswitchable conductance
Jian-Zhen Liao, Jian-Fei Chang, Lingyi Meng, Hai-Long Zhang, Sa-Sa Wanga and Can-Zhong Lu
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC05150F, Communication

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Simplified structure eases antibiotic synthesis

New analogues of the potent antibiotic teixobactin could be instrumental in the fight against multi-drug resistant pathogens.

By replacing a rare amino acid in the structure of teixobactin, UK researchers have unlocked the door to cheaper and easier-to-manufacture forms of this potent antibiotic.

(Left) Teixobactin. (Right) General structure of teixobactin analogues with the hydrophilic/charged residues shown in red, hydrophobic residues shown in black and structural differences shown in blue.

Scientists in the US reported their discovery of teixobactin in 2015. It works against multi-drug resistant pathogens, but as it contains a rare and difficult to manufacture amino acid it is hard to make.

Read the full story by Tabitha Watson on Chemistry World.

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HOT ChemComm articles for June

All of the referee-recommended articles below are free to access until 5th August 2017.

Chemically individual armoured bioreporter bacteria used for the in vivo sensing of ultra-trace toxic metal ions
Zhijun Zhang, Enguo Ju, Wei Bing, Zhenzhen Wang, Jinsong Rena and Xiaogang Qu
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC03794E, Communication

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Expeditious synthesis of pyrano[2,3,4-de]quinolines via Rh(III)-catalyzed cascade C–H activation/annulation/lactonization of quinolin-4-ol with alkynes
Gang Liao, Hong Song, Xue-Song Yinab and Bing-Feng Shi
Chem. Commun., 2017, Advance Article
DOI:  10.1039/C7CC04113F, Communication

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Autonomously propelled microscavengers for precious metal recovery
Sarvesh Kumar Srivastava, Mariana Medina-Sáncheza and Oliver G. Schmidta
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC02605F, Communication

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Aromatic stacking – a key step in nucleation
Aurora J. Cruz-Cabeza, Roger J. Davey, Sharlinda Salim Sachithananthan, Rebecca Smith, Sin Kim Tang, Thomas Vetter and Yan Xiao
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC02423A, Communication

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Hexagonal boron nitride nanosheets as a multifunctional background-free matrix to detect small molecules and complicated samples by MALDI mass spectrometry
Jianing Wang, Jie Sun, Jiyun Wang, Huihui Liu, Jinjuan Xue and Zongxiu Nie
Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7CC02957H, Communication

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Faradaic oxygen evolution from SrTiO3 under nano- and femto-second pulsed light excitation
D. J. Aschaffenburg, X. Chen and T. Cuk
Chem. Commun., 2017,53, 7254-7257
DOI: 10.1039/C7CC03061D, Communication

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Bismuth drug structure solved

Crystal structure of bismuth subgallate viewed along (a) [010] and (b) [100]. Bismuth, carbon and oxygen atoms are coloured purple, grey and red, respectively. Hydrogen atoms and water molecules in the pores have been omitted for clarity.

Bismuth subgallate – a widely used pharmaceutical for treating stomach ulcers – is a porous coordination polymer, new research shows. The discovery, made by scientists in Sweden and the UK, settles a long running question over the drug’s structure, which had been frustrated by bismuth subgallate’s tiny crystals and their tendency to break down when exposed to high energy electron beams.

Now, Andrew Kentaro Inge from Stockholm University and his team have overcome these issues. By combining continuous rotational data collection with a cooling technique, they avoided the electron beam damage, poor resolution and diffuse scattering holding them and others back. ‘Continuous rotation electron diffraction is a promising way to elucidate the structures of hard to obtain, or very hard to crystallise, pharmaceutical forms. For this purpose, it’s an up-and-coming method,’ says Tomislav Friŝĉić, an expert in materials chemistry at McGill University in Canada.

Read the full story by Tabitha Watson on Chemistry World.

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