Looking back at 2020, we would like to share with you some of the great research that has been published in RSC Advances over the year. We are proud to present a selection of the most popular 2020 organic chemistry papers, reviews and HOT articles published so far.
We hope you enjoy reading these articles and as always, all our articles are open access – free to read and accessible to everyone.
| 2020 HOT articles |
Over the year, our reviewers and Associate Editors have handpicked articles of particular interest and marked them as HOT. We are very pleased to highlight some outstanding 2020 organic chemistry HOT articles:
Fluoxetine scaffold to design tandem molecular antioxidants and green catalysts
Giovanni Ribaudo, Laura Orian et al., DOI: 10.1039/D0RA03509B
Giovanni Ribaudo, Marco Bortoli, Alberto Ongaro, Erika Oselladore, Alessandra Gianoncelli, Giuseppe Zagotto and Laura Orian
‘In this paper, we describe the synthesis of some fluoxetine analogues incorporating a selenium nucleus. Selenium is the key oligoelement present in the enzymes involved in the antioxidant endogenous defense system. We have chosen fluoxetine because it is a very important antidepressant, better known with its commercial name ‘Prozac’. The mechanistic details of the enhanced antioxidant potential of our designed compounds were unraveled combining nuclear magnetic resonance (NMR), electrospray ionization-mass spectrometry (ESI-MS), and quantum chemistry calculations.’
Read the interview with the authors about their article here.
More HOT articles
One-pot synthesis of indoles and quinolinones from ortho-tosylaminophenyl-substituted para-quinone methides
Junwei Wang, Lihong Hu et al., DOI: 10.1039/D0RA05497F
Copper-catalyzed synthesis of α-ketoamides using water and dioxygen as the oxygen source
Yuanyuan Xiao, Fang Xiao et al., DOI: 10.1039/D0RA05921H
Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
Qianfa Jia, Qiao Ren et al., DOI: 10.1039/D0RA05251E
One-pot method for the synthesis of 1-aryl-2-aminoalkanol derivatives from the corresponding amides or nitriles
Jan Otevrel, Pavel Bobal et al., DOI: 10.1039/D0RA04359A
Iodine-catalyzed efficient synthesis of xanthene/thioxanthene-indole derivatives under mild conditions
Weihang Miao, Xuequan Wang et al., DOI: 10.1039/D0RA05217E
Synthesis of highly substituted tetrahydroquinolines using ethyl cyanoacetate via aza-Michael–Michael addition
Arunan Palanimuthu, Gene-Hsian Lee et al., DOI: 10.1039/D0RA01264E
Read the full HOT article collection
| Most popular 2020 articles |
Reviews
CuAAC-ensembled 1,2,3-triazole-linked isosteres as pharmacophores in drug discovery: review
Alisha Rani, Jandeep Singh et al., DOI: 10.1039/C9RA09510A
Asymmetric catalysis in direct nitromethane-free Henry reactions
Lin Dong and Fen-Er Chen, DOI: 10.1039/C9RA10263A
Phosphorus-containing amino acids with a P–C bond in the side chain or a P–O, P–S or P–N bond: from synthesis to applications
Mathieu Arribat, Emmanuelle Rémond et al., DOI: 10.1039/C9RA10917J
Papers
A molecular electron density theory study of the participation of tetrazines in aza-Diels–Alder reactions
Luis R. Domingo, Patricia Pérez et al., DOI: 10.1039/D0RA01548B
Self-assembly and multifunctionality of peptide organogels: oil spill recovery, dye absorption and synthesis of conducting biomaterials
Monikha Chetia, Sunanda Chatterjee et al., DOI: 10.1039/C9RA10395C
K2S2O8 mediated C-3 arylation of quinoxalin-2(1H)-ones under metal-, photocatalyst- and light-free conditions
Nibedita Baruah Dutta, Gakul Baishya et al., DOI: 10.1039/D0RA00013B
A concise method for fully automated radiosyntheses of [18F]JNJ-46356479 and [18F]FITM via Cu-mediated 18F-fluorination of organoboranes
Gengyang Yuan, Anna-Liisa Brownell et al., DOI: 10.1039/D0RA04943C
Rhodium-catalyzed phosphorylation reaction of water-soluble disulfides using hypodiphosphoric acid tetraalkyl esters in water
Mieko Arisawa, Masahiko Yamaguchi et al., DOI: 10.1039/D0RA02377A
Cu/TEMPO catalyzed dehydrogenative 1,3-dipolar cycloaddition in the synthesis of spirooxindoles as potential antidiabetic agents
Chitrala Teja, Fazlur Rahman Nawaz Khan et al., DOI: 10.1039/D0RA01553A
Photoinitiated decarboxylative C3-difluoroarylmethylation of quinoxalin-2(1H)-ones with potassium 2,2-difluoro-2-arylacetates in water
Yanhui Gao, Lei Wang et al., DOI: 10.1039/D0RA02059A
Cembrane-type diterpenoids from the gum resin of Boswellia carterii and their biological activities
Xiaowei Sun, Jinqian Yu et al., DOI: 10.1039/C9RA09776G
The mechanochemical Scholl reaction as a versatile synthesis tool for the solvent-free generation of microporous polymers
Annika Krusenbaum, Lars Borchardt et al., DOI: 10.1039/D0RA05279E
Synthesis of a coumarin derivative of resorcin[4]arene with solvent-controlled chirality
Anna Szafraniec and Waldemar Iwanek, DOI: 10.1039/D0RA00368A
Microwave-assisted synthesis, biological evaluation and molecular docking studies of new coumarin-based 1,2,3-triazoles
Ravinder Dharavath, G. Prashanthi et al., DOI: 10.1039/D0RA01052A
Third-generation ionic liquids with N-alkylated 1,4-diazabicyclo[2.2.2]octane cations and pelargonate anions
Anna Turguła, Juliusz Pernak et al., DOI: 10.1039/D0RA00766H
Chiral mono- and dicarbamates derived from ethyl (S)-lactate: convenient chiral solvating agents for the direct and efficient enantiodiscrimination of amino acid derivatives by 1H NMR spectroscopy
Federica Balzano and Gloria Uccello-Barretta, DOI: 10.1039/D0RA00200C
Fluorene benzothiadiazole co-oligomer based aqueous self-assembled nanoparticles
J. Schill, L. Brunsveld et al., DOI: 10.1039/C9RA09015K
Isosorbide bis(methyl carbonate) synthesis from isosorbide and dimethyl carbonate: the key role of dual basic–nucleophilic catalysts
José R. Ochoa-Gómez, Olga Gómez-Jiménez-Aberasturi et al., DOI: 10.1039/D0RA03552A
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