Biocatalysis is helping to drive more sustainable chemical manufacturing through selective, low-energy transformations using enzymes and microbial systems. This selection of articles from Green Chemistry highlights advances in enzyme engineering, chemoenzymatic and multi-enzyme cascades, whole-cell biocatalysis, continuous-flow processes, and biomass valorisation, while showcasing innovative routes to renewable chemicals and bio-based products.
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A novel nutritional induction strategy flexibly switching the biosynthesis of food-like products from methane by a methanotrophic bacterium
Zixi Gao; Shuqi Guo; Yunhao Chen; Hansen Chen; Rongzhan Fu; Qiaoqiao Song; Shen Li; Wenyong Lou; Daidi Fan; Yin Li; Shihui Yang; Ramon Gonzalez; Qiang Fei Green Chem. (2024) 26 (12): 7048–7058. |
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Bioprocess development and scale-up for cis,cis-muconic acid production from glucose and xylose by Pseudomonas putida
Sekgetho C. Mokwatlo; Bruno C. Klein; Pahola Thathiana Benavides; Eric C. D. Tan; Colin M. Kneucker; Chen Ling; Christine A. Singer; Robert Lyons; Violeta Sànchez i Nogué; Kelley V. Hestmark; Morgan A. Ingraham; Kelsey J. Ramirez; Christopher W. Johnson; Gregg T. Beckham; Davinia Salvachúa Green Chem. (2024) 26 (19): 10152–10167. |
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Chemoenzymatic synthesis of amino-esters as precursors of ammonium salt-based surfactants from 5-hydroxymethylfurfural (HMF)
Carlos Moriana Herraiz; Karen S. Arias; Maria J. Climent; Sara Iborra; Avelino Corma Green Chem. (2024) 26 (16): 9118–9131. |
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Dehydration in water: solid-supported lipases as green catalysts for esterification
Rohan M. Thomas; Monica S. Lopez Lemus; Krithika Ganesh; David B. Obbard; Karthikeyan Sivashanmugam; Ganesh Sambasivam; Yang Yang; Bruce H. Lipshutz Green Chem. (2024) 26 (17): 9320–9329. |
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Monoliths enabling biocatalysis in flow chemistry
Aleksandra Lambarska; Katarzyna Szymańska; Ulf Hanefeld Green Chem. (2024) 26 (21): 10718–10738. |
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Constructing a chemoenzymatic strategy for enhancing the efficiency of selectively transforming 5-hydroxymethylfurfural into furan carboxylic acids
Zhiyu Zhang; Xiaowang Zhang; Siyu Qi; Qi Na; Kaichen Zhao; Ziyi Yu; Zhuotao Tan; Hanjie Ying; Chenjie Zhu Green Chem. (2025) 27 (3): 642–649. |
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Biotransformation of C20- and C22-polyunsaturated fatty acids and fish oil hydrolyzates to R,R-dihydroxy fatty acids as lipid mediators using double-oxygenating 15R-lipoxygenase
Jin Lee; Yoon-Joo Ko; Jin-Byung Park; Deok-Kun Oh Green Chem. (2024) 26 (8): 4665–4676. |
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Continuous-flow chemo-enzymatic gram-scale synthesis of indole-3-acetic acid
Sippakorn Mapinta; Sirus Kongjaroon; Duangthip Trisrivirat; Chatchai Kesornpun; Jie Wu; Pimchai Chaiyen; Nopphon Weeranoppanant Green Chem. (2025) 27 (3): 793–803. |
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Design and engineering of biosynthetic and regeneration pathways for central sulfate donors: toward the sustainable production of bioactive sulfated products
Ruirui Xu; Fengling Yang; Weiquan Ding; Xiaoyuan Sun; Yaoqi Tian; Jian Chen; Zhen Kang Green Chem. (2026) 28 (5): 2220–2234. |
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Advances and challenges in fatty acid photodecarboxylases: towards greener chemistry applications?
Eman Bassiony; Aikaterini Margariti; Bekir Engin Eser; Selin Kara Green Chem. (2026). Newly published |
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