Click through to read the Themed Collection online Molecular Design for Reduced Toxicity guest edited by Paul Anastas, Julie Zimmerman and Adelina Voutchkova-Kostal.
Molecular design for reduced toxicity is an area of green chemistry which seeks to increase our understanding and enable the design of molecules across structural classes and applications that can provide the required functions, without the undesirable toxicity.
Safer by Design
Paul T. Anastas and Julie B. Zimmerman
Green Chem., 2016,18, 4324-4324
DOI: 10.1039/C6GC90074G
Probabilistic diagram for designing chemicals with reduced potency to incur cytotoxicity
Longzhu Q. Shen, Richard S. Judson, Fjodor Melnikov, John Roethle, Aditya Gudibanda, Julie B. Zimmerman and Paul T. Anastas
Green Chem., 2016,18, 4461-4467
DOI: 10.1039/C6GC01058J
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
Fabian A. Grimm, Yasuhiro Iwata, Oksana Sirenko, Grace A. Chappell, Fred A. Wright, David M. Reif, John Braisted, David L. Gerhold, Joanne M. Yeakley, Peter Shepard, Bruce Seligmann, Tim Roy, Peter J. Boogaard, Hans B. Ketelslegers, Arlean M. Rohde and Ivan Rusyn
Green Chem., 2016,18, 4407-4419
DOI: 10.1039/C6GC01147K
