This review by Maria Barbi and colleagues from the “Multiscale Modelling of Living Matter” group covers many aspects of DNA packaging in viruses, bacteria through to eukaryotes. The review discusses the electrostatic interactions of DNA, proteins and ions; mechanisms of DNA compaction; the way different condensation mechanisms are implemented in vivo; functional tuning of DNA compaction and finally gives an evolutionary perspective on the subject.
Electrostatics of DNA compaction in viruses, bacteria and eukaryotes: functional insights and evolutionary perspective
Soft Matter, 2012, 8, 9285
DOI: 10.1039/c2sm25789k (free to read for a short time)
This review is from the Polyelectrolytes in Soft Matter and Biology themed issue. Click on the link to view the entire themed issue.