This Hot Review looks at the natural and versatile polymer hyaluronic acid (HA). Hyaluronic acid is a component of the extracellular matrix and is employed in many biological processes. Because of the bio-compatibility of HA, it is an important building block in biomaterials. This article looks at recent efforts in using HA in drug releasing hydrogels, which are promising materials for tissue repair and regeneration.
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Hyaluronic acid-based hydrogels: from a natural polysaccharide to complex networks
Xian Xu , Amit K. Jha , Daniel A. Harrington , Mary C. Farach-Carson and Xinqiao Jia
Soft Matter, 2012, 8, 3280-3294, DOI: 10.1039/C2SM06463D