Hot Articles: Temperature sensitive triblocks and Double-hydrophilic Diblocks plus Synthetic surgical sealants

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triblock copolymerTriblock copolymers: Temperature-sensitive polymer aqueous solutions showing sol-to-gel transition with temperature increase have drug delivery, tissue engineering and post-operative applications. Sequence control of the triblock copolymers studied here was observed to influence the different transitions from alpha-helix to random coils, cylindrical bundles or spherical micelles at different temperatures. Soo Hyun Park, Bo Gyu Choi, Hyo Jung Moon, So-Hye Cho and Byeongmoon Jeong, Soft Matter, 2011, DOI: 10.1039/C1SM05505D.

Double-hydrophilic block copolymers: The formed diblock copolymers undergo unusual aqueous (micro)phase separation of binary mixtures of two biocompatible hydrophilic homopolymers. This is one of the few reports on block copolymer self-assembly in aqueous solution. Adam Blanazs, Nicholas J. Warren, Andrew L. Lewis, Steven P. Armes and Anthony J. Ryan, Soft Matter, 2011, DOI: 10.1039/C1SM05771E.

surgical sealantSoft tissue sealants: A new family of copolymers were derived from poly(glycerol sebacate) and lactic acid and when used in surgical sealants exhibited significantly higher adhesive strengths than fibrin sealants or synthetic PleuraSeal(TM) for wound dressing. The materials also had improved cytocompatibility. Qizhi Chen, Shuling Liang and George A. Thouas, Soft Matter, 2011, DOI: 10.1039/C1SM05350G.

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