Natural Products Blog

Natural Products in OBC

29 Sep 2011

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry. We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

The latest natural products’ related articles in OBC Issue 20 have been collated here:

Total synthesis of the proposed structures of the DNA methyl transferase inhibitors peyssonenynes, and structural revision of peyssonenyne B
Patricia García-Domínguez, Ilaria Lepore, Cathie Erb, Hinrich Gronemeyer, Lucia Altucci, Rosana Álvarez and Ángel R. de Lera
Org. Biomol. Chem., 2011, 9, 6979-6987
DOI: 10.1039/C1OB05932G, Paper

A flexible and unified strategy for syntheses of cladospolides A, B, C, and iso-cladospolide B
Debjani Si, Narayana M. Sekar and Krishna P. Kaliappan
Org. Biomol. Chem., 2011, 9, 6988-6997
DOI: 10.1039/C1OB05787A, Paper

Resolving natural product epimer spectra by matrix-assisted DOSY
Ralph W. Adams, Juan A. Aguilar, Julia Cassani, Gareth A. Morris and Mathias Nilsson
Org. Biomol. Chem., 2011, 9, 7062-7064
DOI: 10.1039/C1OB06097J, Paper

New apocarotenoids and β-carotene cleavage in Blakeslea trispora
Alejandro F. Barrero, M. Mar Herrador, Pilar Arteaga, Jesús Gil, Jose-Antonio González, Eugenio Alcalde and Enrique Cerdá-Olmedo
Org. Biomol. Chem., 2011, 9, 7190-7195
DOI: 10.1039/C1OB05712J, Paper

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Latest issue online – flavonoids, SAM enzymes, hypervalent iodine regants and diterpenoids

23 Sep 2011

By Francesca Burgoyne.

Issue 10 is now available online, featuring some of our regular reviews from Peter Roach, Nigel Veitch and Jim Hanson. Also in the issue, the latest Hot off the Press article from Robert Hill and Andrew Sutherland and an interesting review from Berit Olofsson on hypervalent iodine reagents in NP synthesis:

Flavonoids and their glycosides, including anthocyanins
Nigel C. Veitch and Renée J. Grayer, Nat. Prod. Rep., 2011, 28, 1626

Radical S-adenosylmethionine enzymes: Mechanism, control and function
Martin R. Challand, Rebecca C. Driesener and Peter L. Roach, Nat. Prod. Rep., 2011, 28, 1696

Hypervalent iodine reagents in the total synthesis of natural products
Luiz F. Silva, Jr., Berit Olofsson, Nat. Prod. Rep., 2011, 28, 1722

Diterpenoids of terrestrial origin
James R. Hanson, Nat. Prod. Rep., 2011, 28, 1755

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RSC e-membership now launched

02 Sep 2011

By Francesca Burgoyne.

This week, the RSC launched a new product, RSC e-membership, allowing anyone to access an electronic version of Chemistry World through a MyRSC account and to enjoy the benefits of electronic networking via this professional online community for £20/year.

Subscribers to this do not benefit from the professional recognition or any of the other many services and discounts available to RSC Members, but it allows chemists from around the world, many already members of another chemical society in their own country, to benefit from the highly-esteemed content in Chemistry World and the networking opportunities offered from MyRSC, which now stands at over 11,000 members. The RSC e-membership also allows subscribers to join a virtual specialist interest group on MyRSC. If you are interested in joining, please visit www.rsc.org/emembership.

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NPR Issue 9 now available online

22 Aug 2011

By Francesca Burgoyne.

The latest issue of Natural Product Reports is now online, and features a review from Ronald J. Quinn et al. on the cover. Their article examines Protein Fold Topology correlations between natural products and biosynthetic enzymes and therapeutic targets and suggests that this could explain why nature produces such a large proportion of existing drugs.

Also in the issue we have an article from Alvaro M. Vijoen on natural products in anti-obesity therapy, a review from Muhammad Saleem and Karsten Krohn on difficulties in developing new naturally derived antibiotics, and a regular review article from Braulio M. Fraga on natural sesquiterpenoids.

View the issue

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NPR Lecture Award presented at ASP 2011

16 Aug 2011

By Francesca Burgoyne.

The NPR Lecture Award was presented to 2011 winner Christian Hertweck at the Annual Meeting of the American Society for Pharmacognosy in San Diego last month. Professor Christian Hertweck from the Leibniz Institute for Natural Product Research in Jena, Germany was selected for his contribution to the field of biosynthesis.

: NPR Editorial Board Chair Professor Bradley Moore presents Professor Christian Hertweck with his award. Photograph courtesy of Andrew Schultz

The NPR Lecture Award is awarded to a researcher who has made a significant contribution to the field of natural products and who has also had some involvement with the journal. Professor Hertweck has authored a number of articles for NPR and you can view his most recent articles below:

The chemistry and biology of cytochalasans
Kirstin Scherlach, Daniela Boettger, Nicole Remme and Christian Hertweck
Nat. Prod. Rep., 2010, 27, 869-886

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork
Christian Hertweck, Andriy Luzhetskyy, Yuri Rebets and Andreas Bechthold
Nat. Prod. Rep., 2007, 24, 162-190

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Natural Product Reports Issue 8 now online

21 Jul 2011

By Francesca Burgoyne.

The latest issue of NPR is now available to view online here.

The front cover illustrates a review from Massimo E. Maffei describing recent developments in the study of biosynthesis and medicinal applications of plant VOCs.

In this issue you will also find our regular Hot off the Press feature from Robert Hill and Andrew Sutherland covering current developments in bioorganic chemistry and novel natural products, such as virgatolide A from Pestalotiopsis virgatula and a Highlight article from Hans-Georg Sahl and Karin Thevissen on recent reports of specific defensin targets.

M. Soledade C. Pedras focuses on the phytoalexins produced by cruciferous plants and Annabel C. Murphy discusses the use of metabolic engineering for improving the sustainability of the chemical industry. Finally natural products containing a diazo group are reviewed by Christopher J. Moody while Steven V. Ley discusses those containing the piperazic acid motif.

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Natural products in OBC

13 Jul 2011

By Francesca Burgoyne.

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry. We will try to keep you updated here, but for all the latest articles why not sign up to OBC’s free e-alert and receive the table of contents directly to your inbox every time an issue is published?

The latest natural products’ related articles in OBC Issue 15 have been collated here:

A [Pd]-mediated ω-alkynone cycloisomerization approach for the central tetrahydropyran unit and the synthesis of C(31)–C(48) fragment of aflastatin A
Sachin B. Narute, Neella Chandra Kiran and Chepuri V. Ramana
Org. Biomol. Chem., 2011, 9, 5469-5475
DOI: 10.1039/C1OB05251A

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins
Sonsoles Martín-Santamaría, Sabine André, Eliza Buzamet, Rémi Caraballo, Gloria Fernández-Cureses, Maria Morando, João P. Ribeiro, Karla Ramírez-Gualito, Beatriz de Pascual-Teresa, F. Javier Cañada, Margarita Menéndez, Olof Ramström, Jesús Jiménez-Barbero, Dolores Solís and Hans-Joachim Gabius
Org. Biomol. Chem., 2011, 9, 5445-5455
DOI: 10.1039/C0OB01235A

Kopsihainanines A and B, two unusual alkaloids from Kopsia hainanensis
Jia Chen, Jian-Jun Chen, Xiaojun Yao and Kun Gao
Org. Biomol. Chem., 2011, 9, 5334-5336
DOI: 10.1039/C1OB05724C

Want to see your natural products article featured on this blog? Submit it online here.

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Natural Products Blog

Natural Products in OBC

Latest issue online – flavonoids, SAM enzymes, hypervalent iodine regants and diterpenoids

Top ten most accessed articles in August

RSC e-membership now launched

Top ten most accessed articles in July

Top ten most accessed articles in June

NPR Issue 9 now available online

NPR Lecture Award presented at ASP 2011

Natural Product Reports Issue 8 now online

Natural products in OBC

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