Author Archive

Top ten most accessed articles in June

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Synthetic approaches toward sesterterpenoids
Daniel T. Hog, Robert Webster and Dirk Trauner
Nat. Prod. Rep., 2012, 29, 752-779
DOI: 10.1039/C2NP20005H

Assessing calcareous sponges and their associated bacteria for the discovery of new bioactive natural products
Mélanie Roué, Elodie Quévrain, Isabelle Domart-Coulon and Marie-Lise Bourguet-Kondracki
Nat. Prod. Rep., 2012, 29, 739-751
DOI: 10.1039/C2NP20040F

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Strained cyclophane natural products: Macrocyclization at its limits
Tanja Gulder and Phil S. Baran
Nat. Prod. Rep., 2012, 29, 899-934
DOI: 10.1039/C2NP20034A

Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects
Hajer Abdelkafi and Bastien Nay
Nat. Prod. Rep., 2012, 29, 845-869
DOI: 10.1039/C2NP20037F

Triterpenoids
Robert A. Hill and Joseph D. Connolly
Nat. Prod. Rep., 2012, 29, 780-818
DOI: 10.1039/C2NP20027A

Hypervalent iodine reagents in the total synthesis of natural products
Luiz F. Silva, Jr. and Berit Olofsson
Nat. Prod. Rep., 2011, 28, 1722-1754
DOI: 10.1039/C1NP00028D

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

Diterpenoids of terrestrial origin
James R. Hanson
Nat. Prod. Rep., 2012, 29, 890-898
DOI: 10.1039/C2NP20051A

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

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Top ten most accessed articles in May

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 617-621
DOI: 10.1039/C2NP90016E

Bacterial volatiles: the smell of small organisms
Stefan Schulz and Jeroen S. Dickschat
Nat. Prod. Rep., 2007, 24, 814-842
DOI: 10.1039/B507392H

The early stages of taxol biosynthesis: An interim report on the synthesis and identification of early pathway metabolites
Jennifer Guerra-Bubb, Rodney Croteau and Robert M. Williams
Nat. Prod. Rep., 2012, 29, 683-696
DOI: 10.1039/C2NP20021J

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Triterpenoids
Robert A. Hill and Joseph D. Connolly
Nat. Prod. Rep., 2012, 29, 780-818
DOI: 10.1039/C2NP20027A

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

Pheromones, attractants and other chemical cues of aquatic organisms and amphibians
Scott F. Cummins and John H. Bowie
Nat. Prod. Rep., 2012, 29, 642-658
DOI: 10.1039/C2NP00102K

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, 29, 622-641
DOI: 10.1039/C2NP00073C

The isoprenoid-precursor dependence of Plasmodium spp.
Jan-Ytzen van der Meer and Anna K. H. Hirsch
Nat. Prod. Rep., 2012, 29, 721-728
DOI: 10.1039/C2NP20013A

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Top ten most accessed articles in April

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

NMR in natural products: understanding conformation, configuration and receptor interactions
Teresa Carlomagno
Nat. Prod. Rep., 2012, 29, 536-554
DOI: 10.1039/C2NP00098A

Cytotoxic and antioxidant marine prenylated quinones and hydroquinones
Suthananda N. Sunassee and Michael T. Davies-Coleman
Nat. Prod. Rep., 2012, 29, 513-535
DOI: 10.1039/C2NP00086E

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

Pheromones, attractants and other chemical cues of aquatic organisms and amphibians
Scott F. Cummins and John H. Bowie
Nat. Prod. Rep., 2012, 29, 642-658
DOI: 10.1039/C2NP00102K

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 435-439
DOI: 10.1039/C2NP90008D

Insights from the sea: Structural biology of marine polyketide synthases
David L. Akey, Jennifer J. Gehret, Dheeraj Khare and Janet L. Smith
Nat. Prod. Rep., 2012, Advance Article
DOI: 10.1039/C2NP20016C

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, 29, 622-641
DOI: 10.1039/C2NP00073C

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Why not take a look at the articles today and blog your thoughts and comments below.

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Top ten most accessed articles in March

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 435-439
DOI: 10.1039/C2NP90008D

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Cytotoxic and antioxidant marine prenylated quinones and hydroquinones
Suthananda N. Sunassee and Michael T. Davies-Coleman
Nat. Prod. Rep., 2012, 29, 513-535
DOI: 10.1039/C2NP00086E

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms
Zhao-Li Zhou, Ya-Xi Yang, Jian Ding, Yuan-Chao Li and Ze-Hong Miao
Nat. Prod. Rep., 2012, 29, 457-475
DOI: 10.1039/C2NP00088A

Phenazines and cancer
A. Cimmino, A. Evidente, V. Mathieu, A. Andolfi, F. Lefranc, A. Kornienko and R. Kiss
Nat. Prod. Rep., 2012, 29, 487-501
DOI: 10.1039/C2NP00079B

Key achievements in the total synthesis of vibsane-type diterpenoids
Jeffrey Y. W. Mak and Craig M. Williams
Nat. Prod. Rep., 2012, 29, 440-448
DOI: 10.1039/C2NP00067A

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation
Yukari Fujimoto, Ambara Rachmat Pradipta, Naohiro Inohara and Koichi Fukase
Nat. Prod. Rep., 2012, 29, 568-579
DOI: 10.1039/C2NP00091A

Why not take a look at the articles today and blog your thoughts and comments below.

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Top ten most accessed articles in February

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

Electrophilic and nucleophilic enzymatic cascade reactions in biosynthesis
Barbara T. Ueberbacher, Mélanie Hall and Kurt Faber
Nat. Prod. Rep., 2012, 29, 337-350
DOI: 10.1039/C2NP00078D

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 129-133
DOI: 10.1039/C1NP90052H

The chemical ecology of cyanobacteria
Pedro N. Leão, Niclas Engene, Agostinho Antunes, William H. Gerwick and Vitor Vasconcelos
Nat. Prod. Rep., 2012, 29, 372-391
DOI: 10.1039/C2NP00075J

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Key achievements in the total synthesis of vibsane-type diterpenoids
Jeffrey Y. W. Mak and Craig M. Williams
Nat. Prod. Rep., 2012, 29, 440-448
DOI: 10.1039/C2NP00067A

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms
Zhao-Li Zhou, Ya-Xi Yang, Jian Ding, Yuan-Chao Li and Ze-Hong Miao
Nat. Prod. Rep., 2012, 29, 457-475
DOI: 10.1039/C2NP00088A

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, Advance Article
DOI: 10.1039/C2NP00073C

Why not take a look at the articles today and blog your thoughts and comments below.

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Top ten most accessed articles in January

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 129-133
DOI: 10.1039/C1NP90052H

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

The chemical ecology of cyanobacteria
Pedro N. Leão, Niclas Engene, Agostinho Antunes, William H. Gerwick and Vitor Vasconcelos
Nat. Prod. Rep., 2012, 29, 372-391
DOI: 10.1039/C2NP00075J

Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis
Madan K. Kharel, Pallab Pahari, Micah D. Shepherd, Nidhi Tibrewal, S. Eric Nybo, Khaled A. Shaaban and Jürgen Rohr
Nat. Prod. Rep., 2012, 29, 264-365
DOI: 10.1039/C1NP00068C

Biosynthesis of 3,5-AHBA-derived natural products
Qianjin Kang, Yuemao Shen and Linquan Bai
Nat. Prod. Rep., 2012, 29, 243-263
DOI: 10.1039/C2NP00019A

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, Advance Article
DOI: 10.1039/C2NP00073C

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Why not take a look at the articles today and blog your thoughts and comments below.

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Top ten most accessed articles in December

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Beyond ethylmalonyl-CoA: The functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity
Micheal C. Wilson and Bradley S. Moore
Nat. Prod. Rep., 2012, 29, 72-86
DOI: 10.1039/C1NP00082A

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Sesquiterpene synthases: Passive catalysts or active players?
David J. Miller and Rudolf K. Allemann
Nat. Prod. Rep., 2012, 29, 60-71
DOI: 10.1039/C1NP00060H

Aminobenzoates as building blocks for natural product assembly lines
Christopher T. Walsh, Stuart W. Haynes and Brian D. Ames
Nat. Prod. Rep., 2012, 29, 37-59
DOI: 10.1039/C1NP00072A

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1879-1882
DOI: 10.1039/C1NP90043A

The diazofluorene antitumor antibiotics: Structural elucidation, biosynthetic, synthetic, and chemical biological studies
Seth B. Herzon and Christina M. Woo
Nat. Prod. Rep., 2012, 29, 87-118
DOI: 10.1039/C1NP00052G

Macrocylic bisbibenzyl natural products and their chemical synthesis
David C. Harrowven and Sarah L. Kostiuk
Nat. Prod. Rep., 2012, 29, 223-242
DOI: 10.1039/C1NP00080B

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

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Building a nation of scientists

Goverdhan MehtaGoverdhan Mehta talks to Sheena Elliott and Elinor Richards about the progress of science in India and the challenges scientists face

Goverdhan Mehta is a researcher, specialising in organic synthesis. He has helped to build institutions in India – the Indian Institute of Technology, Kanpur, the University of Hyderabad, and the Indian Institute of Science, Bangalore. He was director of the Indian Institute of Science (1998-2005) and vice chancellor of the University of Hyderabad (1994-1998).

Your research is focused on organic chemistry. What attracted you to that field?

There is something intrinsically fascinating about organic chemistry. In my early high school years, when I was exposed to interesting chemical structures, I was attracted to them. I had a sense of appreciation for art and organic molecules to me provided a wonderful expression of art at a molecular level.

What are your main achievements in the field?

I have worked in many areas of organic chemistry, but it’s synthesis that’s given me the greatest pleasure. As organic chemistry advanced, different contemporary challenges came to my attention. The main driver for me to pursue those challenges was the intricacy of the target structure synthesis. There was also an element of expectation that perhaps our research might become useful to society. We continue to need new drugs for a variety of disorders, so we synthesised a large number of natural products; many of them are biologically active and it is quite possible that some of them can provide leads for new drug discovery.

Over the last few years, I have become interested in how to address a problem that the ageing population is facing – neurodegeneration. It has been shown that some natural products can slow down neurodegeneration. In some cases, there is also an indication that they can help restore lost cognitive function. So I have been working on the synthesis of such lead molecules. As I’m getting older, I recognise the need for doing something in that area!

You’ve won numerous awards. Which achievements are you most proud of?

I don’t think that awards and recognition have necessarily brought me a great sense of joy. They do bring a sense of satisfaction because your peers have recognised your work. But I don’t think any serious researcher works for awards. It is the sheer joy of research that keeps people going. Recognition has come my way, but don’t think that I can equate that with the joy of doing research.

What are the challenges facing scientists in India and how could these be overcome?

Scientists all over the world are facing challenges on two fronts. The first problem is that scientists are not being supported by society as much as they should and some governments are not always forthcoming in terms of providing budgetary support. The second problem is that scientists, and science in general, have become isolated both in terms of discipline and, to some extent, in terms of geographical location. This is being redressed now with increasing international collaborations, so in the geographical sense, the isolation is being reduced. But I think disciplinary isolation vis a vis other knowledge streams and fragmentation of science is still a serious challenge.

It is a good time for scientists in India because the government is very supportive of science. Funding is no longer as serious a problem as it is in other parts of the world. Recently, our prime minister said that the budget for science will be almost doubled over the next few years. But I’m not too sure that we as a scientific community are steering science in India in the direction that it ought to be heading. I believe that the government and the scientific community must set a goal that in the next 10 years, India will be among the world’s leading scientific countries.

What is your opinion on the perception that Indian science and research is falling behind the rest of the world, following recent comments by Prime Minister Manmohan Singh?

Prime Minister Singh’s statement referred mainly to China. China has made more progress in science and technology than India. Scientific productivity in India has increased, but not as much as in China. Since we are behind, to simply say that we are walking and walking well is not enough. We should be galloping to catch up. My judgement is that our progress is not commensurate with the support that the government is providing, and not commensurate with the capacity, capability, enthusiasm and the vibrancy that our youth have. We can achieve much more.

How do the different industries compare (the pharmaceutical industry in particular or the more general chemical industry)?

It is only over the last 10 or 12 years, since the economic reforms, that industry in India has grown at such a rate so as to be in a position to invest in research and development. I expect that investment by industry is going to rise; however, the current level of investment is not in an acceptable range. There are certain sectors – pharma, for example – and some other chemical industries, where I think India’s potential is immense, but there are some challenges with the policies that are being pursued. We have to devise a well thought out strategy.

The prime minister’s Science Advisory Council reported that there is an absence of any Indian universities among the world’s best. What is your opinion on the quality of universities in India?

I’m not a great believer in the ranking systems being followed, but the fact is that no Indian university features among the top few hundred universities. However, if we were to look at undergraduate teaching, India has institutions that produce graduates through excellent teaching and training. The graduates are probably as good as they are anywhere else in the world. If you were to grade an institution on the quality of undergraduates, I would say that the Indian Institutes of Technology rank among the top 10 institutions in the world. But, if you bring in research and other elements, they will not feature anywhere near the top. So the quality of research is a serious problem. I think it is high time that the scientific community and scientific leadership in our country sort out an effective, implementable strategy to make a major shift.

You experienced difficulty obtaining a visa to travel to the US in 2006, when you were invited to give a lecture at the University of Florida. At the time, a report from the National Academy of Sciences in the US said that at least 3000 scientists had faced a similar problem. Have things improved since then or do you believe that the visa problem is hampering scientific progress and career development for scientists?

It was ironic that I and a leading scientist from the US, Jane Lubchenco (who at that time was president of the International Council for Science before I succeeded her), wrote an editorial about the principle of universatility of science and the visa regime in Science a few months before this happened. We wrote that it was important for the international growth of science that scientists were able to travel. Little did I realise that soon I would be a victim of this! I think the situation has improved, but a lot more needs to be done. While the US National Academy of Sciences is playing a very positive role towards this end, the academies can only do the advocacy. Eventually, it is the government and the state department of security staff that makes the final judgement.

If you have any spare time, how do you fill it?

For most scientists, and I’m no exception, your research is a hobby. What other profession can give you that pleasure and privilege? In a previous interview, I was asked what I would wish for. I said we Indians believe in rebirth and so the only wish I have is that if I were to be born again, I would be a scientist. I would like to be a chemist, hopefully a better one.

Read the original article and see Professor Mehta’s recent RSC published papers at Chemistry World

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Top ten most accessed articles in November

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1879-1882
DOI: 10.1039/C1NP90043A

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Aminobenzoates as building blocks for natural product assembly lines
Christopher T. Walsh, Stuart W. Haynes and Brian D. Ames
Nat. Prod. Rep., 2012, 29, 37-59
DOI: 10.1039/C1NP00072A

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Natural products and Pharma 2011: Strategic changes spur new opportunities
Guy T. Carter
Nat. Prod. Rep., 2011, 28, 1783-1789
DOI: 10.1039/C1NP00033K

Isoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis
Jeroen S. Dickschat
Nat. Prod. Rep., 2011, 28, 1917-1936
DOI: 10.1039/C1NP00063B

Sesquiterpene synthases: Passive catalysts or active players?
David J. Miller and Rudolf K. Allemann
Nat. Prod. Rep., 2012, 29, 60-71
DOI: 10.1039/C1NP00060H

The diazofluorene antitumor antibiotics: Structural elucidation, biosynthetic, synthetic, and chemical biological studies
Seth B. Herzon and Christina M. Woo
Nat. Prod. Rep., 2012, 29, 87-118
DOI: 10.1039/C1NP00052G

Multitargeting by curcumin as revealed by molecular interaction studies
Subash C. Gupta, Sahdeo Prasad, Ji Hye Kim, Sridevi Patchva, Lauren J. Webb, Indira K. Priyadarsini and Bharat B. Aggarwal
Nat. Prod. Rep., 2011, 28, 1937-1955
DOI: 10.1039/C1NP00051A

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Why not take a look at the articles today and blog your thoughts and comments below.

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Dean Tantillo wins 2012 NPR Lecture Award

Dean TantilloWe are delighted to announce that Professor Dean Tantillo from the University of California, Davis (USA) is the winner of the 2011 NPR Lecture Award. Professor Tantillo was selected for his work in the field of enzymology.

“It is an honor to be chosen as the 2012 NPR lecturer,” Professor Tantillo commented on receiving the award. “My students at UC Davis have worked hard to show how theoretical chemistry can contribute to natural products research and I am delighted that a fantastic journal like NPR supports this growing part of the natural products community. Thanks!”

The conference at which the lecture will be delivered will be announced in due course.

The NPR Lecture Award is awarded to a researcher who has made a significant contribution to the field of natural products and who has also had some involvement with the journal. You can view Professor Tantillo’s recent article for NPR below:

Biosynthesis via carbocations: Theoretical studies on terpene formation
Dean J. Tantillo
Nat. Prod. Rep., 2011, 28, 1035-1053
DOI: 10.1039/C1NP00006C

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