A new recyclable copper catalyst has been developed which could be reused 20 times in the Diels-Alder reaction in ionic liquids without any obvious loss of activity or enantioselectivity.
Homogeneous metal-catalysed reactions are widely employed in organic synthesis. However, because most catalysts are expensive and because the metal
Zhi-Ming Zhou and colleagues from China report a series of imidazolium-tagged C2-symmetric bis(oxazoline) copper catalysts. These catalysts were applied to the Diels-Alder reaction and achieved high levels of activity and enantioselectivity. Due to the nature of the ligand, these catalysts were soluble in ionic liquids, including the hydrophobic [Bmim]NTf2, which enabled good recyclability. In fact, these catalysts could be recycled at least 20 times without showing an obvious loss in activity or enantioselectivity.
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Recyclable copper catalysts based on imidazolium-tagged C2-symmetric bis(oxazoline) and their application in D–A reactions in ionic liquids, Zhi-Ming Zhou, Zhi-Huai Li, Xiao-Yan Hao, Xiao Dong, Xin Li, Li Dai, Ying-Qiang Liu, Jun Zhang, Hai-feng Huang, Xia Li and Jin-liang Wang, Green Chem., 2011, DOI: 10.1039/C1GC15788D
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