Author Archive

Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry.

We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

The latest natural products’ related articles have been collated here:

  • Limonoids

Kv1.2 potassium channel inhibitors from Chukrasia tabularis
Hong-Bing Liu, Hua Zhang, Ping Li, Yan Wu, Zhao-Bing Gao and Jian-Min Yue
Org. Biomol. Chem., 2012, 10, 1448-1458
DOI: 10.1039/C1OB06666H, Paper

  • Fungal glycolipid

Fusaroside, a unique glycolipid from Fusarium sp., an endophytic fungus isolated from Melia azedarach
Sheng-Xiang Yang, Hong-Peng Wang, Jin-Ming Gao, Qiang Zhang, Hartmut Laatsch and Yi Kuang
Org. Biomol. Chem., 2012, 10, 819-824
DOI: 10.1039/C1OB06426F

  • Pancratistatin analogues

A formal [3+3]-annulation-based approach to pancratistatins: total synthesis of (±)-7-deoxy-pancratistatin and its 2-epi and 2,4-diepi analogues
Olaia Nieto-García, Hugo Lago-Santomé, Fernando Cagide-Fagín, Juan Carlos Ortiz-Lara and Ricardo Alonso
Org. Biomol. Chem., 2012, 10, 825-834
DOI: 10.1039/C1OB06374J, Paper

  •  Bromotyrosine natural products

Syntheses of pseudoceramines A–D and a new synthesis of spermatinamine, bromotyrosine natural products from marine sponges J. Mikael Hillgren, Christopher T. Öberg and Mikael Elofsson
Org. Biomol. Chem., 2012, 10, 1246-1254
DOI: 10.1039/C1OB06722B, Paper

  • Alkaloids synthesis

One-pot reductive coupling of N-acylcarbamates with activated alkenes: application to the asymmetric synthesis of pyrrolo[1,2-a]azepin-5-one ring system and (−)-xenovenine Xue-Kui Liu, Xiao Zheng, Yuan-Ping Ruan, Jie Ma and Pei-Qiang Huang
Org. Biomol. Chem., 2012, 10, 1275-1284
DOI: 10.1039/C1OB06697H, Paper

Want to see your natural products article featured on this blog? Submit it online here

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Meet the NPR team

The NPR team will be attending a number of conferences in 2012 and we would be delighted to meet you.

Dr Marie Cote, Deputy Editor

Dr Richard Kelly, Managing Editor


Here are just some of the conferences where you can meet us in the coming months:

Please let us know if you are planning on attending any of these meetings, as it would be lovely to meet you there!

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Influenza Neuroaminidase on the cover of NPR Issue 1, 2012

Welcome to NPR Issue 1, 2012

Looking back on 2011, we’d like to thank all our authors, readers and referees for what has been another very successful year for Natural Product Reports. A big thanks also goes to the NPR Editorial Board for their great support and enthusiasm.

Read the 2012 Editorial by NPR Chair Professor Bradley Moore and Editor Dr Richard Kelly reflecting on this year’s many highlights and catch a glimpse of what to look ahead to for a bright 2012!



On the cover of this first Issue is the work of Judith M. Rollinger et al., reviewing the increasing research efforts of the past decade on neuroaminidase (NA) for lead discovery strategies from nature, focusing on the structure, function and druggability of influenza NA, and its inhibition by natural products. This review will be free to access for the next 6 weeks.

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
DOI: 10.1039/C1NP00053E

Also in this Issue, read:

     

    We hope you enjoy reading our first issue for this new volume of NPR and we wish you all the warmest Season’s Greetings.

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    Natural Products in OBC

    Organic & Biomolecular Chemistry publishes many articles that cover natural product chemistry. We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

    In OBC Issue 1, 2012 , you will find:

     

     

     

     

    Want to see your natural products article featured on this blog? Submit it online here.

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    Degradation of lignin in bacteria and fungi on the cover of NPR issue 12


    Natural Product Reports’ last issue of the year is now published on line.

    On the cover of this December issue is an article by Timothy Bugg et al. at the University of Warwick (UK), which highlights recent progress in the understanding of the microbial breakdown of lignin, and catabolic pathways for the breakdown of lignin components.

    Also check out our latest Hot of the Press article by Robert A. Hill and Andrew Sutherland, discover the potential of combinatorial biosynthesis in plants, read all about the stereochemical aspects of the biosynthetic pathways to terpenes, and learn on curcumin’s multitargeting powers.

    All of this in a very successful 2011 last issue. We hope you enjoy it!

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    Natural Products in OBC

    Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry. We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

    The latest natural products’ related articles in OBC Issue 23 have been collated here:

    Efficient approach to novel 1α-triazolyl-5α-androstane derivatives as potent antiproliferative agents
    Zalán Kádár, Ádám Baji, István Zupkó, Tibor Bartók, János Wölfling and Éva Frank
    Org. Biomol. Chem., 2011, 9, 8051-8057
    DOI: 10.1039/C1OB06086D, Paper


    Design and synthesis of trans-3-aminopyran-2-carboxylic acid (APyC) and α/β-peptides with 9/11-helix
    Gangavaram V. M. Sharma, Kodeti Srinivas Reddy, Shaik Jeelani Basha, Kondreddi Ravinder Reddy and Akella V. S. Sarma
    Org. Biomol. Chem., 2011, 9, 8102-8111
    DOI: 10.1039/C1OB06279D, Paper


    6,6-Spiroimine analogs of (−)-gymnodimine A: synthesis and biological evaluation on nicotinic acetylcholine receptors
    Leslie Duroure, Thierry Jousseaume, Rómulo Aráoz, Elvina Barré, Pascal Retailleau, Laurent Chabaud, Jordi Molgó and Catherine Guillou
    Org. Biomol. Chem., 2011, 9, 8112-8118
    DOI: 10.1039/C1OB06257C, Paper



    Want to see your natural products article featured on this blog? Submit it online here.

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    NPR Issue 11 now available online


    The latest issue of Natural Product Reports is now available online and features a review by Andrew M. Harned and Kelly A. Volp (University of Minnesota) on the cover. Their article highlights the sorbicillinoid family of natural products and examines their isolation, biosynthesis, and synthetic studies.

    Also in this issue, a Highlight Article by Guy Carter on Natural products and Pharma 2011: Strategic changes spur new opportunities, and reviews examining glyco(randomization/diversification) strategies, by Richard Gantt et al., and shedding light on the syrbactins’ chemistry and biology, by Daniel Krah et al.

    Why not take a look now! Access the full issue here, or follow the links to the individual articles:

    Natural products and Pharma 2011: Strategic changes spur new opportunities
    Guy T. Carter, Nat. Prod. Rep., 2011, 28, 1783-1789

    The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies
    Andrew M. Harned and Kelly A. Volp, Nat. Prod. Rep., 2011, 28, 1790-1810

    Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules
    Richard W. Gantt, Pauline Peltier-Pain and Jon S. Thorson, Nat. Prod. Rep., 2011, 28, 1811-1853

    The chemistry and biology of syringolins, glidobactins and cepafungins (syrbactins)
    Daniel Krahn, Christian Ottmann and Markus Kaiser, Nat. Prod. Rep., 2011, 28, 1854-1867

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    Natural Products in OBC

    Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry. We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

    The latest natural products’ related articles in OBC Issue 20 have been collated here:

    Total synthesis of the proposed structures of the DNA methyl transferase inhibitors peyssonenynes, and structural revision of peyssonenyne B
    Patricia García-Domínguez, Ilaria Lepore, Cathie Erb, Hinrich Gronemeyer, Lucia Altucci, Rosana Álvarez and Ángel R. de Lera
    Org. Biomol. Chem., 2011, 9, 6979-6987
    DOI: 10.1039/C1OB05932G, Paper

    A flexible and unified strategy for syntheses of cladospolides A, B, C, and iso-cladospolide B
    Debjani Si, Narayana M. Sekar and Krishna P. Kaliappan
    Org. Biomol. Chem., 2011, 9, 6988-6997
    DOI: 10.1039/C1OB05787A, Paper

    Resolving natural product epimer spectra by matrix-assisted DOSY
    Ralph W. Adams, Juan A. Aguilar, Julia Cassani, Gareth A. Morris and Mathias Nilsson
    Org. Biomol. Chem., 2011, 9, 7062-7064
    DOI: 10.1039/C1OB06097J, Paper

    New apocarotenoids and β-carotene cleavage in Blakeslea trispora
    Alejandro F. Barrero, M. Mar Herrador, Pilar Arteaga, Jesús Gil, Jose-Antonio González, Eugenio Alcalde and Enrique Cerdá-Olmedo
    Org. Biomol. Chem., 2011, 9, 7190-7195
    DOI: 10.1039/C1OB05712J, Paper

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