Author Archive

Challenge for analysing preservative effectiveness in cosmetics

The authors explain how the challenge test works, its historical context and interpret the results using pharmacopoeia criterion.

The challenge test predicts the antimicrobial abilities of cosmetic preservatives over a prolonger period of time. Salgado and colleagues critique the efficacy of the challenge test for analysisng preservative effectiveness in this critical review.

Read it for free until the 1st April.

The use of the challenge test to analyse preservative efficiency in non-sterile cosmetic and health products: applications and critical points
F. A. M. Fiorentino, M. Chorilli and H. R. N. Salgado
Anal. Methods, 2011
DOI: 10.1039/C0AY00597E

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Chemical imaging of active pharmaceutical ingredients

Slobodan Šašić  and colleagues from Pfizer describe the use of microspectroscopic chemical imaging with white light optical microscopic imagery for monitoring the agglomeration of pharmaceutical ingredients during the manufacturing process, in this HOT paper.

In a separate paper, Šašić compares the performance of three chemical mapping and imaging platforms to determine the distribution of the active pharmaceutical ingredient in various pharmaceutical products.

Both Analytical Methods papers are free to access until the 1st March using the links below:

Monitoring of API particle size during solid dosage form manufacturing process by chemical imaging and particle sizing
Slobodan Šašić, Weili Yu and Lin Zhang
Anal. Methods, 2011
DOI: 10.1039/c0ay00562b

Parallel imaging of active pharmaceutical ingredients in some tablets and blends on Raman and near-infrared mapping and imaging platforms
Slobodan Šašić
Anal. Methods, 2011
DOI: 10.1039/c0ay00532k

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Separation of proteins using new short monoPLOT columns

Last week we published the latest paper from Analytical Methods Editor-in-Chief, Brett Paull.

The paper will be free to access until the end of the month.

Monolithic porous layer open tubular (monoPLOT) columns for low pressure liquid chromatography of proteins
Ekaterina Nesterenko, Oksana Yavorska, Mirek Macka, Alexander Yavorskyy and Brett Paull
Anal. Methods, 2011
DOI: 10.1039/c0ay00649a

A new form of short monolithic porous layer open tubular columns have been applied to the low pressure liquid chromatographic separation of proteins.

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