In a recent communication, triterpenoids are used as scaffolds in supramolecular self-assembly and recognition. Conjugates of molecules based on glycyrrhetinic acid form dimers held together through 6-hydrogen bonding pairs. The supramolecular dimeric structure was able to recognise and encapsulate polar molecules in aprotic solvents through its suitably sized cavity.
This unique dimer may have the potential to encage molecules with medicinal activity, and thus be used as a novel biomaterial.
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Jun Hu, Jinrong Lu, Ruofan Li and Yong Ju, Soft Matter, 2011, (Advance Article), DOI: 10.1039/C0SM01392G, Communication