Hot Article: Supramolecular assembly of glycyrrhetinic acid conjugates form dimers that can host a guest molecule

In a recent communication, triterpenoids are used as scaffolds in supramolecular self-assembly and recognition. Conjugates of mSynthesis and Self-Assembly Properties of A Glycyrrhetinic Acid Conjugate Containing Uracil and 2,6-Diaminopyridine Unitsolecules based on glycyrrhetinic acid form dimers held together through 6-hydrogen bonding pairs. The supramolecular dimeric structure was able to recognise and encapsulate polar molecules in aprotic solvents through its suitably sized cavity.

This unique dimer may have the potential to encage molecules with medicinal activity, and thus be used as a novel biomaterial.
Read this Soft Matter article for free (until February 24, 2011) here.

Jun Hu, Jinrong Lu, Ruofan Li and Yong Ju, Soft Matter, 2011, (Advance Article), DOI: 10.1039/C0SM01392G, Communication

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