HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Graphical Abstract

Label-free Raman imaging of the macrophage response to the malaria pigment hemozoin
Alison J. Hobro, Nicolas Pavillon, Katsumasa Fujita, Muge Ozkan, Cevayir Coban and Nicholas I. Smith
Analyst, 2015, 140, 2350-2359
DOI: 10.1039/C4AN01850H

Calculation of Raman Optical Activity Spectra for Vibrational Analysis
Shaun T. Mutter, François Zielinski, Paul L. A. Popelier and Ewan W. Blanch
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02357A

Rapid identification of goblet cells in unstained colon thin sections by means of quantum cascade laser-based infrared microspectroscopy

N. Kröger-Lui, N. Gretz, K. Haase, B. Kränzlin, S. Neudecker, A. Pucci, A. Regenscheit, A. Schönhals and W. Petrich
Analyst, 2015, 140, 2086-2092
DOI: 10.1039/C4AN02001D

Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo
Huadong Xu, Panli Zuo, Shirong Wang, Li Zhou, Xiaoxuan Sun, Meiqin Hu, Bin Liu, Qihui Wu, Haiqiang Dou, Bing Liu, Feipeng Zhu, Sasa Teng, Xiaoyu Zhang, Li Wang, Qing Li, Mu Jin, Xinjiang Kang, Wei Xiong, Changhe Wang and Zhuan Zhou
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02074J

Universal Enantioselective Discrimination by Raman Spectroscopy
Johannes Kiefer and Kristina Noack
Analyst, 2015, 140, 1787-1790
DOI: 10.1039/C4AN02218A
Graphical Abstract
Sensitive Assay of Trypsin Using Poly(thymine)-Templated Copper Nanoparticles as Fluorescent Probes

Li-Juan Ou, Xiao-Yan Li, Li-Juan Li, Hong-Wei Liu, Ai-Ming Sun and Kai-Jian Liu
Analyst, 2015, 140, 1871-1875
DOI: 10.1039/C4AN01994F

Testing and validating electroanalytical simulations
Enno Kätelhön and Richard G. Compton
Analyst, 2015, 140, 2592-2598
DOI: 10.1039/C4AN02276A

Fast IR laser mapping ellipsometry for the study of functional organic thin films
Andreas Furchner, Guoguang Sun, Helge Ketelsen, Jörg Rappich and Karsten Hinrichs
Analyst, 2015, 140, 1791-1797
DOI: 10.1039/C4AN01853B

A new method for wavelength interval selection that optimizes locations, widths and combinations of the intervals intelligently
Bai-Chuan Deng, Yong-Huan Yun, Pan Ma, Chen-Chen Lin, Da-Bing Ren and Yi-Zeng Liang
Analyst, 2015, 140, 1876-1885
DOI: 10.1039/C4AN02123A

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HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Graphical Abstract

Rapid biodiagnostic ex vivo imaging at 1 μm pixel resolution with thermal source FTIR FPA
C. R. Findlay, R. Wiens, M. Rak, J. Sedlmair, C. J. Hirschmugl, Jason Morrison, C. J. Mundy, M. Kansiz and K. M. Gough
Analyst, 2015, 140, 2493-2503
DOI: 10.1039/C4AN01982B

Controlled growth of immunogold for amplified optical detection of aflatoxin B1
Xu Wang, Reinhard Niessner and Dietmar Knopp
Analyst, 2015, 140, 1453-1458
DOI: 10.1039/C4AN02281E

A Comparative Study of Graphene-Hydrogel Hybrid Bionanocomposites for Biosensing

S. L. Burrs, D. C. Vanegas, M. Bhargava, N. Mechulan, P. Hendershot, H. Yamaguchi, C. Gomes and E. S. McLamore
Analyst, 2015, 140, 1466-1476
DOI: 10.1039/C4AN01788A

Pre-Equlibration Kinetic Size-Exclusion Chromatography with Mass Spectrometry Detection (peKSEC-MS) for Label-Free Solution-Based
Jiayin Bao, Svetlana M. Krylova, Leonid T. Cherney, J. C. Yves Le Blanc, Patrick Pribil, Philip E. Johnson, Derek J. Wilson and Sergey N. Krylov
Analyst, 2015, 140, 990-994
DOI: 10.1039/C4AN02232G

Forensic determination of blood sample age using a bioaffinity-based assay
Juliana Agudelo, Crystal Huynh and Jan Halámek
Analyst, 2015, 140, 1411-1415
DOI: 10.1039/C4AN02269F
Graphical Abstract
Oxidative damage in DNA bases revealed by UV Resonant Raman spectroscopy

Francesco D’Amico, Francesca Cammisuli, Riccardo Addobbati, Clara Rizzardi, Alessandro Gessini, Claudio Masciovecchio, Barbara Rossi and Lorella Pascolo
Analyst, 2015, 140, 1477-1485
DOI: 10.1039/C4AN02364A

The lipid-reactive oxygen species phenotype of breast cancer. Raman spectroscopy and mapping, PCA and PLSDA for invasive ductal carcinoma and invasive lobular carcinoma. Molecular tumorigenic mechanis
Jakub Surmacki, Beata Brozek-Pluska, Radzislaw Kordek and Halina Abramczyk
Analyst, 2015, 140, 2121-2133
DOI: 10.1039/C4AN01876A

Self-cleaning properties in engineered sensors for dopamine electroanalytical detection

Guido Soliveri, Valentina Pifferi, Guido Panzarasa, Silvia Ardizzone, Giuseppe Cappelletti, Daniela Meroni, Katia Sparnacci and Luigi Falciola
Analyst, 2015, 140, 1486-1494
DOI: 10.1039/C4AN02219J

Near-infrared excited ultraviolet emitting upconverting phosphors as an internal light source in dry chemistry test strips for glucose sensing
T. Valta, V. Kale, T. Soukka and C. Horn
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02028F

Micromotors to capture and destroy anthrax simulant spores
Jahir Orozco, Guoqing Pan, Sirilak Sattayasamitsathit, Michael Galarnyk and Joseph Wang
Analyst, 2015, 140, 1421-1427
DOI: 10.1039/C4AN02169J

Compact 3D-Printed Interface for Coupling Open Digital Microchips with Venturi Easy Ambient Sonic-Spray Ionization Mass Spectrometry
Jie-Bi Hu, Ting-Ru Chen, Chia-Hsien Chang, Ji-Yen Cheng, Yu-Chie Chen and Pawel L. Urban
Analyst, 2015, 140, 1495-1501
DOI: 10.1039/C4AN02220C

Rapid Microstructure Characterization of Polymer Thin Films with 2D-Array Multifocus Raman Microspectroscopy
Ashok Zachariah Samuel, Sohshi Yabumoto, Kenichi Kawamura and Koichi Iwata
Analyst, 2015, 140, 1847-1851
DOI: 10.1039/C4AN01983K
Graphical Abstract
Real-time detection of H5N1 influenza virus through hyperbranched rolling circle amplification

Seyed Vahid Hamidi, Hedayatollah Ghourchian and Gholamreza Tavoosidana
Analyst, 2015, 140, 1502-1509
DOI: 10.1039/C4AN01954G

Nitrogen-Doped Carbon Dots from Plant Cytoplasm as Selective and Sensitive Fluorescent Probes for Detecting P-Nitroaniline in Both Aqueous and Soil Systems
Haoran Yuan, Denian Li, Yan Liu, Xizhe Xu and Chuanxi Xiong
Analyst, 2015, 140, 1428-1431
DOI: 10.1039/C4AN01869A

Simultaneous strain and temperature sensing using slightly tapered optical fiber with inner air-cavity
H. F. Chen, D. N. Wang and Y. Wang
Analyst, 2015, 140, 1859-1862
DOI: 10.1039/C4AN02230K

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Analytical Science Twitter Poster Conference Winners

The Scientific Committee and Chair selected the top four posters presented at #RSCAnalyticalPoster to be awarded poster prizes. Here the winners tell us a little bit more about their research…

Following last month’s Analytical Science Twitter Poster Conference we are delighted to introduce the poster prize winners in this blog post. The event was a great success, featuring work from across the analytical sciences, submitted from all over the world. Around 80 posters were presented during the conference, as well as a couple of videos. Around 380 people took part, asking questions and sharing ideas, with Tweets from Europe, USA, Canada, South America, Africa, Asia and Australia. The science was excellent, subjects presented included diagnosing diseases using nanotechnology, detecting 3rd hand smoke with HPLC, analysing latent fingerprints and microbial metabolomics among many others.

We’d like to say a huge thank you to everyone who took part in the event, in particular the Chair and Scientific Committee for dedicating their time and efforts and making the event such a success!

Chair and Organisers, Matt Baker, University of Strathclyde, UK @ChemistryBaker, Royal Society of Chemistry Analyst @analystrsc, Analytical Methods @MethodsRSC and JAAS @JAASNews. Scientific Committee, Carsten Engelhard, Universität Siegen @EngelhrC, Craig Banks, Manchester Metropolitan University @Act_mmu, Damien Arrigan, Curtin University @arri_aus, Jean-Francois Masson, University of Montreal @Masson_chem, Karen Faulds, University of Strathclyde @FauldsKaren, Martin Resano, University of Zaragoza @MartinResano, Nick Stone, University of Exeter @profnickstone, Perdita Barran, The University of Manchester @PerditaB, Raychelle Burks, Doane College @DrRubidium, Renee JiJi, University of Missouri @ReneeJiJi, Richard Dluhy, University of Georgia @radluhy, Roy Goodacre, The University of Manchester @RoyGoodacre

Many congratulations to the four prize winners of the Analytical Science Twitter Poster Conference!

WINNER

Sarah-Jane Richards

@RichardsSJ

Poster: Cholera and Sugars

My PhD research has focussed on the neutralisation and detection of bacteria and toxins. I am particularly interested in the development of rapid, label-free and inexpensive diagnostics, especially methods for low resource settings, such as in less-developed countries. We use carbohydrate functionalised gold nanoparticles as a colourimetric test for detecting bacteria and toxins and have optimised the particle design so that the method gives rapid readouts in biologically relevant (saline) conditions. We have also shown that this method is compatible with a simple mobile phone camera set up, removing the need for a spectrometer, making the system preferable for use in low resource and low expertise environments.

In the future, I aspire to develop these diagnostic methods into kit-type formats in order to facilitate their use by untrained operators. I am also interested in developing a paper based lateral flow assay for toxin detection, which will further improve the viability of the system in low resource environments by significantly reducing the cost. Having just finished by PhD studies, I am in the process of exploring my options for carrying out post-doctoral research, with a future view to starting my own research group.


RUNNER UP

Zoe Ayres

@ZJAyres

Poster: Heavy metal detection in aqueous environments using a novel diamond-based electrochemical sensor

I am really pleased to be selected as a runner up for the #rscanalyticalposter competition, which has been a great opportunity for me to get my research out to a wider audience. Work involves the development of novel diamond-based electrochemical sensors, capitalising on the material and electrochemical properties of freestanding boron doped diamond (BDD) films, including chemical and mechanical inertness, large solvent window, low background currents and the ability to be processed into any geometry electrode. Focus is currently on the development of Electrochemical-X-ray Fluorescence (EC-XRF), with an aim of ultimately detecting trace heavy metals in-situ, at a lake or riverside. Here the BDD functions as both an electrode, to preconcentrate metals from solution onto the electrode surface and X-ray window, to enable unambigious chemical identification of the metals on the surface and quantification by XRF. My research goals are to develop diamond-based sensors for use in real-world applications, whilst my career plans are to stay within analytical chemistry where I would love to be involved in the R&D of new analytical techniques.

I would like to take the opportunity to thank my supervisor Professor Julie Macpherson and Diamond colleagues in the Warwick Electrochemistry and Interfaces group, as well as Element Six for the growth of the BDD X-ray window electrodes used in this project. Thank also go to EPSRC and Element Six for funding my PhD project (EPSRC Case award EP/L505110/1).


RUNNER UP

James Hands

@MrJamesHands

Poster: Illuminating the Future of Cancer Diagnosis via Serum ATR-FTIR Spectroscopy

James is a Chemistry PhD candidate who is developing rapid spectroscopic methodologies for cancer diagnosis in collaboration with clinical partners at Royal Preston NHS Foundation Trust and The Walton Centre NHS Foundation Trust supported by Brain Tumour North West and the Sydney Driscoll Neuroscience Foundation. His research work has established a robust and highly reproducible diagnostic method for the diagnosis of brain cancer with high sensitivities and specificities using patient sera and ATR-FTIR. James recently developed a stratified diagnostic approach which allows for rapid diagnosis of cancer vs. non-cancer, metastatic cancer vs. organ confined, brain cancer severity and the organ of origin for metastatic disease. This work has resulted in 4 publications and 2 journal front covers. In addition to the 2014 Federation of Analytical Chemistry and Spectroscopy Societies Student Award, he has also been awarded Best Clinical Poster at the British Neuro-oncology Society Annual Meeting 2013 and awarded 2 prizes at the National Health Service (NHS) Research & Innovation Showcase 2013/14 at Royal Preston Hospital, UK. James’ future goals include continuing research in the USA as a postdoctoral researcher in the field of biomedical spectroscopy.


RUNNER UP

Emily-Rose Billinge

@ERBillinge

Poster: Tunable Resistive Pulse Sensing for Bioassays

During my undergraduate degree in neuroscience I was fascinated by the discovery and measurement of biomarkers, especially in relation to making peripheral measurements to analyse the nervous system as, at current, it is very difficult to diagnose disorders of the brain and invasive measurements carry high risk. This led me to take up a PhD researching the development of new technologies and methodologies to be used in bioassays. To do this I anchor a capture probe, termed “aptamers”, to micro and nanoscale beads. Aptamers are sequences of DNA which can bind specific targets in solution, by attaching these to the surface of beads it is possible to have each bead capture the target protein in solution. We then follow and measure this interaction using a nanopore technology allowing us to identify and quantify proteins in solution. The system we use is rapid and is highly portable so it is hoped that one day this could lead towards point-of-care testing in the field.

Following on from this I’d really like a career which involves both scientific measurements and interaction with the public. I also thoroughly enjoy writing and want to improve scientific representation so hopefully in the future I will be able to incorporate this into my future work. For now, however, I’m fairly happy to see where the world takes me with no fixed agenda and enjoy the journey.

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Phone camera checks water for arsenic

Written by Anisha Ratan for Chemistry World

UK scientists have developed a mobile phone-based system to help people avoid drinking water contaminated with arsenic.1 The phone’s camera measures quantum dot fluorescence in response to arsenic, achieving a limit of detection as low as 5μM.

Approximately 57 million people worldwide encounter As(III) concentrations exceeding the World Health Organization (WHO) recommended maximum of 10μg/L on a regular basis. Chronic exposure to this well known carcinogen and poison, which binds to proteins and impairs cell function, is one of the largest environmental health disasters in the world. Finding a portable, easy-to-use method to measure levels of this most toxic form of arsenic in drinking water is therefore vital.

Read the full article in Chemistry World >>>


A step towards Mobile Arsenic measurement for surface waters
Camille Ann De Villiers, Marta C Lapsley and Elizabeth A H Hall
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN02368D

Do you fancy submitting an article to Analyst? Why not submit to us here today or alternatively email us with your suggestions!

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Pittcon 2015 – Will you be there?

Pittcon 2015Will you be at the Pittcon conference on 8-12 March in New Orleans?

If so, we’d love to invite you to join us for coffee at RSC booth #4301 and help celebrate the 30th Anniversary of JAAS!

Browse our books and journals and find out why RSC Publishing is the best home for your research. And enjoy a 30% conference discount on all books on display (or 35% if you are an RSC member).

You could also win an iPad mini – simply sign up for one of our email alerts at booth #4301 to be in with a chance of winning.

The following Editorial staff will be attending Pittcon and would be pleased to meet you and answer your questions:

Rebecca Brodie Rebecca Brodie

Deputy Editor, Analyst, Analytical Methods, JAAS.

Janet Freshwater

Janet Freshwater

Senior Commissioning Editor, Books

We’re delighted to be presenting the Robert Boyle Prize for Analytical Science to Professor Eric Bakker at Pittcon. Join us for his award symposium on Tuesday, March 10, 2015, 1:30 PM, Room 244.

Please feel free to get in touch with us before the conference to arrange a meeting.

We look forward to meeting you in New Orleans!

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Self-cleaning sensors see the light

Written by Simon Neil for Chemistry World

Graphical AbstractScientists in Italy have engineered a cheap and simple electrochemical sensor that cleans itself when exposed to ultraviolet light. Their system offers a route towards self-cleaning electrodes with myriad environmental and biomedical sensing applications – from detecting pollutants in water to monitoring medications in blood.

Open any book on chemical or biological sensors and you’ll find a lot of content on electrochemical devices. This prevalence is testament to the importance and advantages of electrode-based sensing; and electrodes containing nanomaterials are becoming increasingly popular, owing to their high surface-to-volume ratio, which can improve their sensitivity and lower costs.

Read the full article in Chemistry World >>


Self-cleaning properties in engineered sensors for dopamine electroanalytical detection
Guido Soliveri, Valentina Pifferi, Guido Panzarasa, Silvia Ardizzone, Giuseppe Cappelletti, Daniela Meroni, Katia Sparnacci and Luigi Falciola
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02219J

Do you fancy submitting an article to Analyst? Why not submit to us here today or alternatively email us with your suggestions!

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HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Label-free phenotyping of peripheral blood lymphocytes by infrared imaging
M. Verdonck, S. Garaud, H. Duvillier, K. Willard-Gallo and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01855A

Graphical Abstract

PNGase F-mediated incorporation of 18O into glycans for relative glycan quantitation
Wei Zhang, Weiqian Cao, Jiangming Huang, Hong Wang, Ji Wang, Chen Xie and Pengyuan Yang
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02073A

A microelectrochemical biosensor for real-time in vivo monitoring of brain extracellular choline
Keeley L. Baker, Fiachra B. Bolger and John P. Lowry
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02027H

Differentiation of Prostate Cancer from Normal Tissue in Radical Prostatectomy Specimens by Desorption Electrospray Ionization and Touch Spray Ionization Mass Spectrometry
K. S. Kerian, A. K. Jarmusch, V. Pirro, M. O. Koch, T. A. Masterson, L. Cheng and R. G. Cooks
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02039A

Multi-enzyme microreactor-based online electrochemical system for selective and continuous monitoring of acetylcholine
Yuqing Lin, Ping Yu and Lanqun Mao
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02089H

Fluorescence Chemosensors for Hydrogen Sulfide Detection in Biological Systems
Zhi Guo, Guiqiu Chen, Guangming Zeng, Zhongwu Li, Anwei Chen, Jiajia Wang and Longbo Jiang
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01909A

Marker-free automated histopathological annotation of lung tumour subtypes by FTIR-Imaging
Frederik Großerueschkamp, Angela Kallenbach-Thieltges, Thomas Behrens, Thomas Brüning, Matthias Altmayer, Georgios Stamatis, Dirk Theegarten and Klaus Gerwert
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01978D

Universal Electronics for Miniature and Automated Chemical Assays
Pawel L. Urban
Analyst, 2015, Advance Article
DOI:
10.1039/C4AN02013H

Graphical Abstract

Raman microimaging of murine lungs: insight into the vitamin A content
K. M. Marzec, K. Kochan, A. Fedorowicz, A. Jasztal, K. Chruszcz-Lipska, J. Cz. Dobrowolski, S. Chlopicki and M. Baranska
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01881H

Stereospecific recognition and quantitative structure-activity relationship between antibodies and enantiomers: ofloxacin as model hapten
Hongtao Mu, Baoling Wang, Zhenlin Xu, Yuanming Sun, Xinan Huang, Yudong Shen, Sergei A. Eremin, Anatoly V. Zherdev, Boris B. Dzantiev and Hongtao Lei
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02155J

A colorimetric method of analysis for trace amounts of hydrogen peroxide with the use of the nano–properties of Molybdenum disulfide
Xinrong Guo, Yong Wang, Fangying Wu, Yongnian Ni and Serge Kokot
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01950D

Infrared spectral signature of human lymphocyte subpopulations from peripheral blood
N. Wald, A. Legat, C. Meyer, D. E. Speiser and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02247E

Screening and mapping pigments in paintings using scanning electrochemical microscopy (SECM)
Antonio Doménech-Carbó, María Teresa Doménech-Carbó, Miguel Silva, Francisco Manuel Valle-Algarra, José Vicente Gimeno-Adelantado, Francisco Bosch-Reig and Rufino Mateo-Castro
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01911C

Transmission versus transflection mode in FTIR analysis of blood plasma: is the EFSW effect the only reason of the observed spectral distortions?
Emilia Staniszewska-Slezak, Anna Rygula, Kamilla Malek and Malgorzata Baranska
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01842G

Multivariate statistical methodologies applied in biomedical Raman spectroscopy: Assessing the validity of partial least squares regression using simulated model datasets.
Mark E. Keating, Haq Nawaz, Franck Bonnier and Hugh J. Byrne
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02167C

A colorimetric nitrite detection system based on Ag@Au nanoparticles with excellent selectivity and high sensitivity
Tianhua Li, Yonglong Li, Yujie Zhang, Chen Dong, Zheyu Shen and Aiguo Wu
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01583E

Flow-through polymerase chain reaction inside a seamless 3D helical microreactor fabricated utilizing a silicone tube and a paraffin mold
Wenming Wu, Kieu The Loan Trinh and Nae Yoon Lee
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01675K

Graphical Abstract

ß-Cyclodextrin functionalised gold nanoclusters as a luminescent probe for the ultrasensitive detection of dopamine
Rui Ban, E. S. Abdel-Halim, Jianrong Zhang and Jun-Jie Zhu
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02161D

In-vivo and continuous measurement of bisulfide in the hippocampus of rat’s brain by on-line integrated microdialysis/droplet-based microfluidic system
Feidan Gu, Xiaoyu Zhou, Xiaocui Zhu, Meiping Zhao, Jie Hao, Ping Yu and Lanqun Mao
Analyst
, 2015, Advance Article
DOI: 10.1039/C4AN01974A, Paper

Infrared imaging of MDA-MB-231 breast cancer cell line phenotypes in 2D and 3D cultures
Margarita Smolina and Erik Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01833H

High throughput absorbance spectra of cancerous cells: a microscopic investigation of spectral artifacts
A. Mignolet and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01834F

Label-free imaging and identification of typical cells of acute myeloid leukaemia and myelodysplastic syndrome by Raman microspectroscopy
R. Vanna, P. Ronchi, A. T. M. Lenferink, C. Tresoldi, C. Morasso, D. Mehn, M. Bedoni, S. Picciolini, L. W. M. M. Terstappen, F. Ciceri, C. Otto and F. Gramatica
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02127D

Infrared imaging of primary melanoma reveals hints of regional and distant metastases
N. Wald and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01831A

Pituitary gland under infrared light – in search of a representative spectrum for homogenous regions
A. Banas, K. Banas, A. Furgal-Borzych, W. M. Kwiatek, B. Pawlicki and M. B. H. Breese
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01985G

Design of molecularly imprinted conducting polymer protein-sensing films via substrate-dopant binding
Elena Komarova, Matt Aldissi and Anastasia Bogomolova
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01965B

Vibrational signatures to discriminate liver steatosis grades
Chengyuan Peng, Franck Chiappini, Slávka Kaščáková, Mélanie Danulot, Christophe Sandt, Didier Samuel, Paul Dumas, Catherine Guettier and François Le Naour
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01679C

Graphical AbstractCompetitive evaluation of data mining algorithms for use in classification of leukocyte subtypes with Raman microspectroscopy
A. Maguire, I. Vega-Carrascal, J. Bryant, L. White, O. Howe, F. M. Lyng and A. D. Meade
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01887G

Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson’s disease
Michele Morari and Martina Fantin
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01918K

Infrared Micro-spectroscopy for Cyto-pathological Classification of Esophageal Cells
Douglas Townsend, Miloš Miljković, Benjamin Bird, Kathleen Lenau, Oliver Old, Max Almond, Catherine Kendall, Gavin Lloyd, Neil Shepherd, Hugh Barr, Nick Stone and Max Diem
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01884B

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Infrared offers odds on skin cancer spreading

Written by Jennifer Newton for Chemistry World

Scientists in Belgium have shown that infrared spectrometry can help predict how likely it is that a melanoma tumour, the deadliest and most common form of skin cancer, has spread to other organs.

Tumour spread, or metastasis, is the main threat to survival in melanoma patients. However, no biomarkers have been identified to indicate a high risk of metastasis and visual assessment of primary tumours by a trained pathologist is unlikely to reveal if cancerous cells have escaped to other parts of the body.

Graphical Abstract

Read the full article in Chemistry World



Infrared imaging of primary melanoma reveals hints of regional and distant metastases

N. Wald and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01831A

Do you fancy submitting an article to Analyst? Why not submit to us here today or alternatively email us with your suggestions!

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Analytical Science Twitter Poster Conference

#RSCAnalyticalPoster

We are delighted to announce the Analytical Science Twitter Poster Conference (#RSCAnalyticalPoster) will be happening February 5 to February 6 2015!

An image to advertise the twitter conference of Analyst JAAS Analytical Methods

© Shutterstock

The Royal Society of Chemistry Analytical Science Twitter Poster Conference is an online event being held entirely over Twitter to bring members of the analytical research community together to share their research, network and engage in scientific debate.

How do I take part?

During the event simply tweet an image (e.g. JPEG) which will be a digital poster summarising your research along with #RSCAnalyticalPoster and the title of your work. Throughout the day you can then answer any questions posed to you by other people on Twitter and ask questions about other posters. Make sure you follow #RSCAnalyticalPoster throughout the day as the conference progresses.

When is it?

Posters tweeted with #RSCAnalyticalPoster between 9am GMT February 5 and 9am GMT February 6 will be eligible to win an i-pod or RSC book vouchers. Make sure you ask and answer lots of questions to ensure your work is well understood!

An image to advertise the twitter conference of Analyst JAAS Analytical Methods

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Is my research area suitable?

The conference is open to anyone working in any area of analytical science whose research topic is in the scope of Analyst, Analytical Methods or JAAS. If you’re unsure if your poster is suitable for the conference, just get in touch and we can advise.

What can I win?

The main aim of the event is to meet new scientists, share ideas and learn about the latest developments in different areas of analytical science. The scientific committee will also select 3 posters which stimulate wide interest and feature innovative, high quality, exciting analytical research. The top prize will be an i-pod and 2 runners-up will receive a £100 book voucher for the Royal Society of Chemistry Book Shop. Do make sure you also ask lots of questions, meet new people and share your thoughts and ideas about other posters and topics.

Who is organising the event and how do I find them?

At different points throughout the day members of the scientific committee will be logging in to Twitter and searching for #RSCAnalyticalPoster to ask questions about some of the posters. Make sure you check back in at different times to see if you have any new questions and also make sure you ask questions about other posters. Members of the scientific committee and their Twitter names are listed below and make sure you follow us @analystrsc @MethodsRSC and @JAASNews for the latest updates.

Chair and Organisers

Matt Baker, University of Strathclyde, UK @ChemistryBaker

Royal Society of Chemistry

Analyst @analystrsc, Analytical Methods @MethodsRSC and JAAS @JAASNews

Scientific Committee

Carsten Engelhard, Universität Siegen @EngelhrC

An image to advertise the twitter conference of Analyst JAAS Analytical Methods

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Craig Banks, Manchester Metropolitan University @Act_mmu

Damien Arrigan, Curtin University @arri_aus

Jean-Francois Masson, University of Montreal @Masson_chem

Karen Faulds, University of Strathclyde @FauldsKaren

Martin Resano, University of Zaragoza @MartinResano

Nick Stone, University of Exeter @profnickstone

Perdita Barran, The University of Manchester @PerditaB

Raychelle Burks, Doane College @DrRubidium

Renee JiJi, University of Missouri @ReneeJiJi

Richard Dluhy, University of Georgia @radluhy

Roy Goodacre, The University of Manchester @RoyGoodacre

How do I register?

Pre-registration is not necessary; however we will need to verify who you are and where you do your research to be eligible for the prizes. We strongly recommend you do this before the event by emailing us at and letting us know:

  • Your name, address and contact details
  • The title or topic of your poster
  • Your twitter ID

Register for #RSCAnalyticalPoster

We look forward to meeting you in February!

Frequently Asked Questions (will be regularly updated)

Do I need to check the copyright and permissions needed for figures or any other parts of my poster which have already been published?
Yes. Copyright owners have the exclusive right to copy their work and to issue copies of their work to the public, and it is an infringement for anyone else to do so without the copyright owner’s permission. If you are reproducing material contained in a Royal Society of Chemistry publication (journal articles, book or book chapters) you may do so providing that you fully acknowledge the original Royal Society of Chemistry publication and include a link back to it. If you wish to include material that has been published by another publisher, you will need to check how the publisher/copyright owner of the third party material wishes to receive permission requests. Information on this can be found on our Permission Requests page at http://www.rsc.org/Publishing/copyright/permission-requests.asp under “Use of third party material in our publications”.

If I include unpublished work in my poster, will I still be able to publish this in a peer-reviewed journal afterwards?
Subject to the usual conditions outlined in the Licence to Publish, being a part of the Twitter conference will not prevent you using some of the information included in your poster as part of an article in a Royal Society of Chemistry journal. Please note this policy varies by publisher and if you intend to submit your research for publication elsewhere after the event, you should check the individual policy for that journal and publisher.

What size should my poster be?
You can choose any dimensions for your poster, the important thing is that the text and figures are clear for people to read and understand. Using Microsoft PowerPoint, we found a text size of between 12-16 were clear to read when saving an A4 slide as a JPEG and uploading to Twitter. Using an A0 template, the text needed to be between 50 and 60 to be legible. You can use any software you like to create your poster, as long as the image you upload is clear for others to read. We recommend testing your poster on Twitter before the conference to make sure you are happy with your image.

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