Kwang-Seuk Ko, Matthew D. Alexander, Michael D. Burkart and colleagues at University of California at San Diego, give us two different synthetic routes to make one product: the macrolide core of the mycolactone polyketides.
As you can see, organic synthesis is a matter of choice!
Read about the story of these new synthetic methods, the authors’ different approaches to their findings and how they succeded with the synthesis of their targeted molecule.
Free to access until the end of October
Kwang-Seuk Ko, Matthew D. Alexander, Shaun D. Fontaine, James E. Biggs-Houck, James J. La Clair and Michael D. Burkart
Org. Biomol. Chem., 2010, Advance Article
DOI: 10.1039/C0OB00540A, Paper
Read Michael Burkart’s story of this paper on the comments!
