Carlos Perez-Balado and Angel R. de Lera at University of Vigo have designed a convergent and versatile synthetic route to the preparation on this heterodimeric diketopiperazine alkaloid in just 4 steps.
This versatile methodology allows the synthesis of several diastereomers.
The paper is a nice trip through the unexpected paths of organic chemistry that lead you to the right compound. Discover all of this and much more in this HOT paper. We loved it, the referees loved it and I’m sure you will love it too!
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Concise total synthesis and structural revision of (+)-pestalazine B
Carlos Pérez-Balado and Ángel R. de Lera
Org. Biomol. Chem., 2010, Advance Article
DOI: 10.1039/C0OB00531B , Paper
