Lukass Lukasevics completed his Master’s degree in 2019 at Riga Technical University, Latvia. Currently he is working on his Ph.D. thesis under supervision of Dr. Chem. Liene Grigorjeva at Latvian institute of Organic synthesis, Riga, Latvia. His research interests are focused on the development new methodologies for cobalt catalyzed C-H bond functionalization reactions.
Liene Grigorjeva has received her Ph.D. degree from Riga Technical University (Latvia) in 2013, under the supervision of Prof. Aigars Jirgensons. Then she joined Prof. Daugulis group at the University of Houston (USA) as a postdoctoral researcher (2013-2016). Currently she is principal researcher at Latvian Institute of Organic Synthesis and Assistant Professor at Riga Technical University. Her research interests are focused on the development of novel methodology based on C-H bond functionalization under cobalt catalysis.
What motivates your scientific interest in carbonylation?
Direct carbonylation reactions with CO have been immensely exploited both in academic, as well as industrial chemistry. Research in this area has shown its high potential for the synthesis of compounds with a wide range of utility. We believe that cheap, easy to prepare transition metal catalysts could accelerate the development of new methodology for the synthesis of a high value compounds in medicinal and synthetic organic chemistry.
What primary research are you doing in this area?
Our research is focused on the development of novel methodology for C-H functionalization using cobalt catalysis. Interestingly, cobalt catalysts when compared to noble metals display unique reactivity and selectivity which we are excited to explore and apply towards efficient synthetic methodology targeting structurally diverse compounds.
How do you hope this review will help and inspire future research in this area?
C-H functionalization using cobalt catalysis recently has emerged as an attractive alternative to noble metals for their low cost and environmentally friendly properties. With this review we want to highlight the achievements made so far and emphasize that this area is still underdeveloped, thereby promoting researchers to make new developments in this field, hopefully, with industrial applications someday.
Read the full article: Cobalt-catalyzed carbonylation of the C–H bond
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