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Q1 Top Ten most accessed Natural Product Reports articles

During January, February and March this year, the following articles were the Top Ten most accessed:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep  
Nat. Prod. Rep., 2014,31, 160-258
DOI: 10.1039/c3np70117d

Natural product synthesis in the age of scalability
Christian A. Kuttruff, Martin D. Eastgate and Phil S. Baran
Nat. Prod. Rep., 2014,31, 419-432
DOI: 10.1039/c3np70090a

Trying to rationalize total synthesis
Johann Mulzer  
Nat. Prod. Rep., 2014,31, 595-603
DOI: 10.1039/c3np70105k

Natural product isolation – how to get from biological material to pure compounds
Franz Bucar, Abraham Wube and Martin Schmid  
Nat. Prod. Rep., 2013,30, 525-545
DOI: 10.1039/c3np20106f

Industrial natural product chemistry for drug discovery and development
Armin Bauer and Mark Brönstrup
Nat. Prod. Rep., 2014,31, 35-60
DOI: 10.1039/c3np70058e

Diversity, abundance and natural products of marine sponge-associated actinomycetes
Usama Ramadan Abdelmohsen, Kristina Bayer and Ute Hentschel  
Nat. Prod. Rep., 2014,31, 381-399
DOI: 10.1039/c3np70111e

Fungal metabolites with anticancer activity
Antonio Evidente, Alexander Kornienko, Alessio Cimmino, Anna Andolfi, Florence Lefranc, Véronique Mathieu and Robert Kiss  
Nat. Prod. Rep., 2014,31, 617-627
DOI: 10.1039/c3np70078j

Mass spectrometry imaging of plant metabolites – principles and possibilities
Nanna Bjarnholt, Bin Li, Janina D’Alvise and Christian Janfelt  
Nat. Prod. Rep., 2014, Advance Article
DOI: 10.1039/c3np70100j

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
Wilfred A. van der Donk et al.
Nat. Prod. Rep., 2013,30, 108-160
DOI: 10.1039/c2np20085f

Recent progress in neuroactive marine natural products
Ryuichi Sakai and Geoffrey T. Swanson  
Nat. Prod. Rep., 2014,31, 273-309
DOI: 10.1039/c3np70083f

If you have any comments on any of these articles, why not leave these in the comment box below?

Do you have an article you would like to submit to NPR? If so, email us your suggestions today!

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Emily Balskus wins 2014 NPR Emerging Investigator Lectureship


We are delighted to announce that Dr Emily Balskus from Harvard University (USA) is the winner of the 2014 NPR Emerging Investigator Lectureship.

The NPR Lectureship is an annual event which is held at an international meeting, the recipient being a researcher who has made a significant contribution to any natural products-related research in their early independent career.

The conference at which the lecture will be delivered will be announced in due course.

Read more on Emily’s research on the Balskus lab Homepage

Previous winners include:
Rebecca Goss, University of St Andrews, UK (2013 winner)
Dean Tantillo, UC Davis Chemistry, USA (2012 winner)

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Q4 Top Ten most accessed Natural Product Reports articles

During October, November and December, the following articles were the Top Ten most accessed:

Industrial natural product chemistry for drug discovery and development
Armin Bauer and Mark Brönstrup  
Nat. Prod. Rep., 2014,31, 35-60
DOI: 10.1039/c3np70058e

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep  
Nat. Prod. Rep., 2013,30, 237-323
DOI: 10.1039/c2np20112g

Natural product isolation – how to get from biological material to pure compounds
Franz Bucar, Abraham Wube and Martin Schmid  
Nat. Prod. Rep., 2013,30, 525-545
DOI: 10.1039/c3np20106f

Natural products as starting points for the synthesis of complex and diverse compounds
Karen C. Morrison and Paul J. Hergenrother  
Nat. Prod. Rep., 2014,31, 6-14
DOI: 10.1039/c3np70063a

Natural product synthesis in the age of scalability
Christian A. Kuttruff, Martin D. Eastgate and Phil S. Baran  
Nat. Prod. Rep., 2014,31, 419-432
DOI: 10.1039/c3np70090a

Natural compounds with anti-ageing activity
Aikaterini Argyropoulou, Nektarios Aligiannis, Ioannis P. Trougakos and Alexios-Leandros Skaltsounis  
Nat. Prod. Rep., 2013,30, 1412-1437
DOI: 10.1039/c3np70031c

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
Paul G. Arnison, Mervyn J. Bibb, Gabriele Bierbaum, Albert A. Bowers, Tim S. Bugni, Grzegorz Bulaj, Julio A. Camarero, Dominic J. Campopiano, Gregory L. Challis, Jon Clardy et al.
Nat. Prod. Rep., 2013,30, 108-160
DOI: 10.1039/c2np20085f

Hot off the press
Robert A. Hill and Andrew Sutherland  
Nat. Prod. Rep., 2013,30, 1462-1466
DOI: 10.1039/c3np90036c

Impact of copper-catalyzed cross-coupling reactions in natural product synthesis: the emergence of new retrosynthetic paradigms
Gwilherm Evano, Cédric Theunissen and Alexandre Pradal  
Nat. Prod. Rep., 2013,30, 1467-1489
DOI: 10.1039/c3np70071b

Blue flower color development by anthocyanins: from chemical structure to cell physiology
Kumi Yoshida, Mihoko Mori and Tadao Kondo  
Nat. Prod. Rep., 2009,26, 884-915
DOI: 10.1039/b800165k

If you have any comments or thoughts on any of these articles, please leave these in the comment box below.

Do you have an article you would like to submit to Natural Product Reports? Why not submit to us here today or alternatively email us your suggestions!

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Natural Products in Organic & Biomolecular Chemistry – latest selection

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis of alkyl citrate natural products
Mark A. Rizzacasa and Dayna Sturgess
Org. Biomol. Chem., 2014,12, 1367-1382
DOI: 10.1039/C3OB42231C, Review Article; Download PDF

Callyspongisines A–D: bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.
Fabien Plisson, Pritesh Prasad, Xue Xiao, Andrew M. Piggott, Xiao-cong Huang, Zeinab Khalil and Robert J. Capon
Org. Biomol. Chem., 2014,12, 1579-1584
DOI: 10.1039/C4OB00091A, Paper; Download PDF

A rapid and efficient access to renieramycin-type alkaloids featuring a temperature-dependent stereoselective cyclization
Hao Liu, Ruijiao Chen and Xiaochuan Chen
Org. Biomol. Chem., 2014,12, 1633-1640
DOI: 10.1039/C3OB42209G, Paper; Download PDF

Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection
Rajesh K. Pandey, Gregory G. Jarvis and Philip S. Low
Org. Biomol. Chem., 2014,12, 1707-1710
DOI: 10.1039/C3OB41230J, Communication; Download PDF

Towards the diastereoselective synthesis of derivative of 11′-epi-brevipolide H
Gullapalli Kumaraswamy, Neerasa Jayaprakash, Dasa Rambabu, Aniban Ganguly and Rajkumar Banerjee
Org. Biomol. Chem., 2014,12, 1793-1803
DOI: 10.1039/C3OB42367K, Paper; Download PDF

The first convergent total synthesis of penarolide sulfate A2, a novel α-glucosidase inhibitor
Yangguang Gao, Qiuli Shan, Jun Liu, Linlin Wang and Yuguo Du
Org. Biomol. Chem., 2014,12, 2071-2079
DOI: 10.1039/C3OB42364F, Paper; Download PDF

Reaction pathways and free energy profiles for cholinesterase-catalyzed hydrolysis of 6-monoacetylmorphine
Yan Qiao, Keli Han and Chang-Guo Zhan
Org. Biomol. Chem., 2014,12, 2214-2227
DOI: 10.1039/C3OB42464B, Paper; Download PDF

Enzyme-promoted regioselective coupling oligomerization of isorhapontigenin towards the first synthesis of (±)-gnetulin
Wenling Li, Shixia Yang, Teng Lv and Yadong Yang
Org. Biomol. Chem., 2014,12, 2273-2279
DOI: 10.1039/C3OB42456A, Paper; Download PDF

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

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Nominate now for the Natural Product Reports 2014 Lectureship!

 Nominations are now open for the 2014 NPR Emerging Investigator Lectureship.

The Lectureship recognises a researcher who has made a significant contribution to a natural products-related area of the chemical sciences in their early independent career. The winner will deliver their lecture at an international meeting in the coming year.

Nominees should have completed their PhD on or after the 31st December 2001.

To nominate someone simply contact NPR Editor, Richard Kelly. All you need to provide are the name of the nominee and some very brief information about why you are nominating them. Nominations are open to everyone and should be received by 25th February 2014.

The winner will be selected by an Editorial Board panel and the result will be announced in Spring 2014.

The winner for the 2013 Lectureship was Rebecca Goss from University of St Andrews, UK.

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Natural Products in our sister journals: hand-picked for you this month is…

Organic & Biomolecular Chemistry and MedChemComm, our sister journals, publish many articles that cover a variety of natural products-related chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s and MedChemComm‘s e-alerts (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Bioactive prenylated phenyl derivatives derived from marine natural products: novel scaffold for the design of BACE inhibitors
Javier López-Ogalla, Esther García-Palomero, Jorge Sánchez-Quesada, Laura Rubio, Elena Delgado, Pablo García, Miguel Medina, Ana Castro and Pilar Muñoz
Med. Chem. Commun., 2014, Accepted Manuscript

New facile enantio- and diastereo-selective syntheses of (−)-triptonide and (−)-triptolide
Hongrui Zhang, Haifeng Li, Jijun Xue, Rui Chen, Ying Li, Yu Tang and Chunxin Li
Org. Biomol. Chem., 2014,12, 732-736

Regioselective prenylation of bromocarbazoles by palladium(0)-catalysed cross coupling – synthesis of O-methylsiamenol, O-methylmicromeline and carquinostatin A
Claudia Thomas, Olga Kataeva, Arndt W. Schmidt and Hans-Joachim Knölker
Org. Biomol. Chem., 2014,12, 872-875

Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone)
Katrin Schünemann, Daniel P. Furkert, Eun Cho Choi, Stephen Connelly, John D. Fraser, Jonathan Sperry and Margaret A. Brimble
Org. Biomol. Chem., 2014,12, 905-912

Ethynylbenzenoid metabolites of Antrodia camphorata: synthesis and inhibition of TNF expression
Marco Buccini, Kathryn A. Punch, Belinda Kaskow, Gavin R. Flematti, Brian W. Skelton, Lawrence J. Abraham and Matthew J. Piggott
Org. Biomol. Chem., 2014,12, 1100-1113

Biocatalyst mediated regio- and stereo-selective hydroxylation and epoxidation of (Z)-α-santalol
Pankaj P. Daramwar, Prabhakar Lal Srivastava, Swati P. Kolet and Hirekodathakallu V. Thulasiram
Org. Biomol. Chem., 2014,12, 1048-1051

Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90
Bridie L. Dutton, Russell R. A. Kitson, Sarah Parry-Morris, S. Mark Roe, Chrisostomos Prodromou and Christopher J. Moody
Org. Biomol. Chem., 2014,12, 1328-1340

We hope you enjoy this selection! Let us know what you think…
… and why not submit your latest natural product research to OBC or MedChemComm today?

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New Editorial Board Members for Natural Product Reports

We are very pleased to welcome two new members to our Editorial Board this month: Professor Julia Kubanek (Georgia Institute of Technology, USA) and Professor Wen Liu (Shanghai Institute of Organic Chemistry, China).


Professor Julia Kubanek

Prof. Kubanek received her Ph.D. in Organic Chemistry in 1998 from the University of British Columbia. Following this she held postdoctoral positions at the Scripps Institution of Oceanography, University California San Diego (1998–2000) and the University of North Carolina at Wilmington (2000–2001). In 2001 she joined the Georgia Institute of Technology becoming a Professor in 2011.

Her current areas of interest include:

Aquatic chemical ecology; Chemical signaling; Chemical communication; Marine natural products chemistry; Chemical biology; Secondary metabolism; Drug discovery; Plankton ecology; Metabolomics

I’ve been reading Natural Product Reports since I was a graduate student in the early 1990’s. I’m pleased to join the NPR family as a member of the Editorial Board and looking forward to working with authors to bring important research to the attention of the natural products chemistry community.” Prof. Julia Kubanek



Professor Wen Liu

Prof. Wen Liu obtained his Ph.D. degree from the Chinese Academy of Medical Sciences (Peking Union Medical School) in 2000. After postdoctoral studies at the Department of Chemistry, University of California, Davis (2000-2001), and the School of Pharmacy, University of Wisconsin-Madison (2001-2003), he joined the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences in 2003.

His research interests focus on:
1) natural product biosynthesis (genetics, biochemistry and chemistry)
2) combinatorial biosynthesis for production improvement and structural diversity
3) genome and/or transcriptome mining for discovery of novel microbial natural products

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Natural Product Reports at conferences in 2014

Dr Marie Cote, Deputy Editor

Dr Richard Kelly, Managing Editor

The Natural Product Reports team will be attending a number of conferences in 2014 and we would be delighted to meet you there.

We’re also the team behind Natural Product Reports’ sister journals Organic & Biomolecular Chemistry, MedChemComm, and the latest addition to the portfolio, Toxicology Research, so we’ll happily discuss your interdisciplinary research work. In fact, many of our authors choose to publish their research across all of these titles.

Here are just some of the conferences where you can meet us in the coming months:


GRC marine natural products 2-7 March Ventura, CA, USA – Meet Rich

Society of Toxicology annual meeting 23-27 March Phoenix, USA – Meet Marie

National Organic Symposium Trust 11-14 April Agra, India – Meet Rich

ISMSC-9 7-11 June Shanghai, China – Meet Marie

GRC Bioorganic Chemistry 8-13 June Proctor Academy, USA – Meet Rich

BOSS XIV 13-18 July Louvain-la-Neuve, Belgium – Meet Marie

Fall ACS meeting 10-14 August San Francisco, USA – Meet Rich

Gregynog Young Chemists’ Workshop 10-12 September Gregynog, Wales – Meet Marie

EFMC-ISMC 7-10 September Lisbon, Portugal – Meet Rich

Eurotox 7-9 September Edinburgh, UK – Meet Marie

 

Let us know if you are planning on attending any of these meetings, as we would be happy to meet you there!

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Natural Products in OBC – Our latest selection

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural products-related chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94
Lauge Farnaes, James J. La Clair and William Fenical
Org. Biomol. Chem., 2014,12, 418-423

Synthesis of crambescin B carboxylic acid, a potent inhibitor of voltage-gated sodium channels
Atsuo Nakazaki, Yuki Ishikawa, Yusuke Sawayama, Mari Yotsu-Yamashita and Toshio Nishikawa
Org. Biomol. Chem., 2014,12, 53-56

Nickel-catalyzed dimerization of pyrrolidinoindoline scaffolds: systematic access to chimonanthines, folicanthines and (+)-WIN 64821
Mitsuhiro Wada, Takahisa Murata, Hideaki Oikawa and Hiroki Oguri
Org. Biomol. Chem., 2014,12, 298-306

Evolution of an oxidative dearomatization enabled total synthesis of vinigrol
Qingliang Yang, Cristian Draghici, Jon T. Njardarson, Fang Li, Brandon R. Smith and Pradipta Das
Org. Biomol. Chem., 2014,12, 330-344

Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway
Vincent Duplan, Christelle Serba, Jose Garcia, Gaëlle Valot, Sofia Barluenga, Mélanie Hoerlé, Muriel Cuendet and Nicolas Winssinger
Org. Biomol. Chem., 2014,12, 370-375

The first synthesis of (−)-isoambreinolide, (+)-vitexifolin D and (+)-vitedoin B
Hanane Bouanou, Rubén Tapia, M. José Cano, Jose M. Ramos, Esteban Alvarez, Ettahir Boulifa, Abdelaziz Dahdouh, Ahmed I. Mansour, Ramón Alvarez-Manzaneda, Rachid Chahboun and Enrique Alvarez-Manzaneda
Org. Biomol. Chem., 2014,12, 667-672

We hope you enjoy this selection! Let us know what you think…
… and why not submit your latest natural product research to OBC today?

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