Natural Products Blog

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Construction of the basic skeleton of ophiobolin A and variecolin
Ke Li, Cheng Wang, Gang Yin and Shuanhu Gao
Org. Biomol. Chem., 2013,11, 7550-7558
DOI: 10.1039/C3OB41693C

Effective synthesis of kynurenine-containing peptides via on-resin ozonolysis of tryptophan residues: synthesis of cyclomontanin B
Clarence T. T. Wong, Hiu Yung Lam and Xuechen Li
Org. Biomol. Chem., 2013,11, 7616-7620
DOI: 10.1039/C3OB41631C

Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae
Jiachen Zi and Reuben J. Peters
Org. Biomol. Chem., 2013,11, 7650-7652
DOI: 10.1039/C3OB41885E

Synthesis of integerrimide A by an on-resin tandem Fmoc-deprotection–macrocyclisation approach
Sirirat Kumarn, Nitirat Chimnoi and Somsak Ruchirawat
Org. Biomol. Chem., 2013,11, 7760-7767
DOI: 10.1039/C3OB41447G

Enantioselective total synthesis of macrolide (+)-neopeltolide
Arun K. Ghosh, Khriesto A. Shurrush and Zachary L. Dawson
Org. Biomol. Chem., 2013,11, 7768-7777
DOI: 10.1039/C3OB41541D

We hope you enjoy this selection! Let us know what you think…
… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Upenamide: trials and tribulations
William P. Unsworth and Richard J. K. Taylor
Org. Biomol. Chem., 2013,11, 7250-7261
DOI: 10.1039/C3OB41519H

Enantioselective synthesis of encecaline-derived potent antimalarial agents
Dipak Harel, Dirk Schepmann, Reto Brun, Thomas J. Schmidt and Bernhard Wünsch
Org. Biomol. Chem., 2013,11, 7342-7349
DOI: 10.1039/C3OB41583J

How a diversity-oriented approach has inspired a new hypothesis for the gabosine biosynthetic pathway. A new synthesis of (+)-gabosine C
Miguel Ángel Fresneda, Ramon Alibés, Josep Font, Pau Bayón and Marta Figueredo
Org. Biomol. Chem., 2013,11, 6562-6568
DOI: 10.1039/C3OB41183D

Synthesis of a C1–C11 fragment of Zincophorin using planar chiral, neutral π-allyl iron complexes  
John P. Cooksey  
Org. Biomol. Chem., 2013, 11, 5117-5126
DOI: 10.1039/C3OB40894A

First synthesis of antitumoral dasyscyphin B
Ali Akhaouzan, Antonio Fernández, Ahmed I. Mansour, Esteban Alvarez, Ali Haidöur, Ramón Alvarez-Manzaneda, Rachid Chahboun and Enrique Alvarez-Manzaneda
Org. Biomol. Chem., 2013,11, 6176-6185
DOI: 10.1039/C3OB41290C

Doubly prenylated tryptamines: cytotoxicity, antimicrobial activity and cyclisation to the marine natural product flustramine A
Santosh Kumar Adla, Florenz Sasse, Gerhard Kelter, Heinz-Herbert Fiebig and Thomas Lindel
Org. Biomol. Chem., 2013,11, 6119-6130
DOI: 10.1039/C3OB40896E

Approach to the functionalized cyclopentane core of marine prostanoids by applying a radical cyclization of β-disubstituted acrylates
Lisa P. T. Hong, Christopher Chak and Christopher D. Donner
Org. Biomol. Chem., 2013,11, 6186-6194
DOI: 10.1039/C3OB41263F

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

The first total synthesis of nhatrangin A
Ahmed Kamal and Saidi Reddy Vangala  
DOI: 10.1039/C3OB40252E, Paper

A stereoselective approach for the southeast segment (C1–C16) of (+)-sorangicin A
Y. Sridhar and P. Srihari
DOI: 10.1039/C3OB40985F, Paper

An efficient chemical synthesis of carboxylate-isostere analogs of daptomycin
Sabesan Yoganathan, Ning Yin, Yong He, Michael F. Mesleh, Yu Gui Gu and Scott J. Miller  
DOI: 10.1039/C3OB40924D, Paper

Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia
Walter Balansa, Robiul Islam, Frank Fontaine, Andrew M. Piggott, Hua Zhang, Xue Xiao, Timothy I. Webb, Daniel F. Gilbert, Joseph W. Lynch and Robert J. Capon
DOI: 10.1039/C3OB40861B, Paper

Humulane-type sesquiterpenoids from Pilea cavaleriei subsp. crenata
Cang-Song Liao, Chun-Ping Tang, Sheng Yao and Yang Ye  
DOI: 10.1039/C3OB40872H, Paper

Directed studies towards the total synthesis of (+)-13-deoxytedanolide: simple and convenient synthesis of the C8–C16 fragment
Sébastien Meiries, Alexandra Bartoli, Mélanie Decostanzi, Jean-Luc Parrain and Laurent Commeiras
DOI: 10.1039/C3OB40674A, Paper

The cascade radical cyclisation approach to prenylated alkaloids: synthesis of stephacidin A and notoamide B
Nigel S. Simpkins, Ilias Pavlakos, Michael D. Weller and Louise Male
DOI: 10.1039/C3OB40979A, Paper

We hope you enjoy this selection! Let us know what you think…

… and why not submit your next natural product research to OBC ?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Concise synthesis of (−)-steviamine and analogues and their glycosidase inhibitory activities
Nadechanok Jiangseubchatveera, Marc E. Bouillon, Boonsom Liawruangrath, Saisunee Liawruangrath, Robert J. Nash and Stephen G. Pyne
DOI: 10.1039/C3OB40374B, Paper

Synthesis of the decalin core of codinaeopsin via an intramolecular Diels–Alder reaction
Mani Ramanathan, Chun-Jui Tan, Wen-Jung Chang, Hui-Hsu Gavin Tsai and Duen-Ren Hou
DOI: 10.1039/C3OB40480C, Paper

Synthesis and antiproliferative activity of selenoindirubins and selenoindirubin-N-glycosides
Friedrich Erben, Dennis Kleeblatt, Marcel Sonneck, Martin Hein, Holger Feist, Thomas Fahrenwaldt, Christine Fischer, Abdul Matin, Jamshed Iqbal, Michael Plötz, Jürgen Eberle and Peter Langer
DOI: 10.1039/C3OB40603B, Paper

Total syntheses of oroidin, hymenidin and clathrodin
Sivappa Rasapalli, Venkatreddy Kumbam, Abasaheb N. Dhawane, James A. Golen, Carl J. Lovely and Arnold L. Rheingold
DOI: 10.1039/C3OB40668G, Communication

Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents
Kyriacos C. Nicolaou and Roman A. Valiulin
DOI: 10.1039/C3OB40654G, Paper

First studies directed towards the diastereoselective synthesis of the BCD tricyclic core of brownin F
Fabien Rodier, Jean-Luc Parrain, Gaëlle Chouraqui and Laurent Commeiras
DOI: 10.1039/C3OB40363G, Paper

Protein engineering of oxidosqualene-lanosterol cyclase into triterpene monocyclase
Cheng-Hsiang Chang, Hao-Yu Wen, Wen-Shiang Shie, Ching-Ting Lu, Meng-Erh Li, Yuan-Ting Liu, Wen-Hsuan Li and Tung-Kung Wu
DOI: 10.1039/C3OB40493E, Paper

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis of (+)-pentamethylsalvianolic acid C
Benjamin L. Alford and Helmut M. Hügel
Org. Biomol. Chem., 2013,11, 2724-2727
DOI: 10.1039/C3OB27478K, Paper

Concise total syntheses of (±)-noruleine and (±)-uleine
Süleyman Patir and Erkan Ertürk
Org. Biomol. Chem., 2013,11, 2804-2810
DOI: 10.1039/C3OB40180D, Paper

A concise approach to the spiroiminal fragment of marineosins
Guang Li, Xun Zhang, Qi Li, Pengju Feng and Yian Shi
Org. Biomol. Chem., 2013,11, 2936-2938
DOI: 10.1039/C3OB40208H, Communication

Highly stereoselective directed reactions and an efficient synthesis of azafuranoses from a chiral aziridine
Hogyu Lee, Jun Hee Kim, Won Koo Lee, Jaeheung Cho, Wonwoo Nam, Jaedeok Lee and Hyun-Joon Ha
Org. Biomol. Chem., 2013,11, 3629-3634
DOI: 10.1039/C3OB27390C, Paper

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?