Archive for the ‘Conference’ Category

Three young chemists honoured at the 8th International Dendrimer Symposium

New Journal of Chemistry sponsored 3 poster prizes at the 8th International Dendrimer Symposium that took place this summer in Madrid, continuing its support of this series of symposia and the dendrimer community in general.

Guang Zhang is a 2nd year Ph.D. student in the group of Klaus Müllen at the MPI for Polymer Research in Mainz, Germany. He is conducting research on polyphenylene dendrimers and their applications for fluorescent blue light emitting diodes. Zhang’s poster reported G1 and G2 dendrimers having triphenylamine on the surface and pyrene in the core, which showed promising properties as blue OLED materials. Guang’s reaction to winning the NJC Poster Prize: “It is a great honor for me to receive the prize. It’s also a big surprise that I can have access to NJC for free for one year.”

Surface Functionalized Polyphenylene Dendrimers for Deep Blue Light  Emitting Diodes
G. Zhang, M. Baumgarten, R. Trattnig, M. Auer, E. J. W. List, K. Müllen

The winner from Spain is Javier Sánchez, who currently is a postdoctoral fellow at the Instituto de Investigación Sanitaria Gregorio Marañón, where he also carried out his Ph.D. research in the group of María Ángeles Muñoz Fernández.  The focus of Javier’s research is anti-HIV activity, but always with an eye to the potential clinical applications. He explains: “I always try to elucidate the mechanisms by which the different dendrimers behave as they do on the HIV-1 cycle.” The research presented at the conference looked at the anti-HIV activity of different carbosilane dendrimers. After development of the dendrimers they were tested using toxicity assays, inflammatory cytokines induction, HIV infection and cell phenotyping by flow cytommetry. This has led to a dendrimer that as a microbicide has anti-HIV activity for different HIV viral strains.

Anti-HIV Activity of Thiol-Ene Carbosilane Dendrimers and Potential Topical Microbicide
J. Sánchez-Rodríguez, L. Díaz, M. Galán, M. Maly, R. Gómez, F. J. de la Mata, J. L. Jiménez, M. A. Muñoz- Fernández

The 3rd winner is from the group of Eric Simanek at Texas Christian University in the USA. Changsuk Lee is now a postdoctoral fellow, after having obtained his Ph.D. under the direction of Daniel Romo at Texas A&M University in 2010. Changsuk works towards the development of drug delivery vehicles by using various sizes and shapes of dendrimers; to date triazine dendrimers are the best delivery vehicles among others tested. The winning poster covered the synthesis of a prodrug platform with paclitaxel, its biodistribution, mice efficacy testing, and molecular dynamic simulations.

Synthesis and Biological Assessment of a Triazine Dendrimer with 16 Paclitaxel Groups
C. Lee, S.-T. Lo, J. Lim, V. C. P. da Costa, S. Ramezani, G. M. Pavan, O. Annuziata, X. Sun, E. E. Simanek

Congratulations to all 3 winners, who received a certificate, RSC book and a one-year NJC subscription.

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Meet NJC team at summer conference season 2013

Summer Conferences are something we can’t afford to miss! The NJC editors will be attending a number of conferences in the coming weeks. We look forward to meeting you!

NJC is proud to support the following conferences:

Denise will represent NJC at the 20th EuCheMS conference on Organometallic Chemistry (EuCOMC), St Andrews, Scotland, 30 June-4 July 2013. NJC is the sponsor of the Young Plenary Lecturer Dr Florence Mongin from the University of Rennes.
18th European Symposium on Organic Chemistry (ESOC 2013) will be held in Marseille, on the Mediterranean coast of France, at the beginning of July (7th to 12th).   The Palais du Pharo Vieux Port will welcome about 900 participants, including NJC Assistant Editor Ling Peng.
NJC Editor-in-chief Wais Hosseini will be at the International Conference on Advanced Complex Inorganic Nanomaterials, to be held in Namur, Belgium (15–19 July).
NJC is delighted to sponsor the Tuesday evening Poster Session at the 16th International Conference on Bio-Inorganic Chemistry (ICBIC), which will take place in Grenoble from 22–26 July 2013.
The exciting chemistry conference for the Asian community, the 15th Asian Chemical Congress (15 ACC), is returning to its birthplace – Singapore – from 19–23 August. NJC Associate Editor Peter Junk will be there.
We are delighted to be partner of the Groupe d’Etude de Chimie Organique (GECO), which will meet for the 54th time this year. This conference, organized by Erwan Le Grognec, will take place in Croisic (France) at the end of August from the 25th to 30th.

If you are planning on attending any of these conferences please don’t hesitate to email the editorial office to arrange a meeting!

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NJC Poster Prizes for Synthetic Organic Chemistry

Synthetic organic chemistry is the common theme of the research projects that were awarded NJC poster prizes at 3 regional meetings held this past spring.

Irene accepts her NJC poster prize presented by Prof. Elisabet Dunach.

Ms Justine Giauffret & Dr Irene Notar-Francesco (in the group of Sylvain Antoniotti at the Institute of Chemistry in Nice) shared the first prize for their work on the tandem cyclosimerisation and thioacylation of 1,6-enynes catalysed by supported noble metal nanoparticles. This poster was presented at the PACA region (southeastern France) meeting of the French Chemical Society (SCF) in April.

The unexpected product obtained by Justine and Irene.

 

Nathalie, winner of the NJC poster Prize.

A month later, on the other side of France in Brittany, Ms Nathalie Camus was awarded the NJC poster prize at the northwestern France regional meeting of the SCF. Nathalie is a doctoral student in the group of Raphael Tripier at the Université de Bretagne Occidentale; her poster presented the C-functionalisation of cyclams to make bifunctional chelating ligands for use in nuclear medicine.

Design of the bifunctional chelating cyclam.

 

Prof. Erick Carreira presents Alexandre with his NJC poster prize.

Moving back to the southeast to Grenoble, Mr Alexandre Cannillo was the NJC poster prize winner at the 3rd Francophone Symposium on Total Synthesis. His award-winning work used domino Petasis Diels-Alder reactions to synthesise enantiopure polycyclic compounds. Alexandre is a graduate student at the Institute on the Chemistry of Natural Substances in Gif-sur-Yvette, working under the direction of Jean-Marie Beau and Stéphanie Norsikian.

Polycyclic compounds synthesised from readily available starting materials by domino reactions.

 

Congratulations to all of our winners! We wish them continuing success with their research projects and a bright future in chemistry.

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NJC at the 96th Canadian Chemistry Conference in Quebec City

Clockwise from upper left: Place Royale, St Louis gate, Chateau Frontignac, old city signs, statue of S Champlain, St Louis street. (Photos by D Parent.)

After the wilderness of Georgian Bay, I was off to discover the old world charm of Quebec City, host of the 96th Canadian Chemistry Conference.

NJC sponsored two of the symposia included in the programming:
— “Novel Aromatic Compounds: Molecular Materials and Devices” organised by Graham Bodwell and Yuming Zhao (both at Memorial University of Newfoundland)
— “Recent Developments in Pincer Chemistry and Multidentate Ligands” organised by Davit Zargarian (University of Montreal), Hairong Guan (University of Cincinnati ) and Dmitiri Gousev (Wilfrid Laurier University )

For inorganic chemists the “place to be” at CCC was the pincer ligands symposium during the 3 days that it was held. It was SRO (“standing room only”) at times, as people came to hear some of the top experts speak, people like Gerard van Koten, Bob Crabtree, Mike Fryzuk, Alan Goldman, Dan Mindiola and Oleg Ozerov, who were the plenary lecturers

The novel aromatic compounds symposium had the feeling of a family reunion—convivial with a faithful crowd in attendance. The topics ranged from synthesis to properties to applications with plenary speakers Remi Chauvin, Ben King, Rik Tykwinski, Thomas Baumgartner, Alex Adronov, Will Skene and Dmitri Perepichka.

Novel Aromatic Compounds speakers' dinner with NJC editor Denise Parent and CCC Scientific Chair Thierry Ollevier.

At the end of each symposium, NJC hosted the speakers’ dinner with the organisers. Chic French cuisine was served up for the organic group, while the inorganic chemists were treated to hearty Quebecois cooking. It looks like everyone had a good time, enjoying the food and the company.

Next year’s meeting will be held in Vancouver from June 1–5. I for one certainly look forward to attending.

Photos from the Pincer Ligands speakers' dinner hosted by NJC. (Photos courtesy of G Wilson.)

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Georgian Bay Day at Killbear Park

After 3 full days, Martin Stillman offered participants in CanBIC-4 a day of R&R in Killbear Provincial Park. Boarding a big yellow school bus (it’s been over 40 years since I last rode one in high school!) we were taken to the park, where we split into 2 groups. I’d opted for the “kayak in the afternoon” group (we’ll see later how that worked out) so my group started the morning with a talk on snakes.

An Eastern Foxsnake found in Ontario

Jimmy, a domesticated Eastern Foxsnake

The star of this “show-and-tell” presentation was undoubtedly Jimmy, an Eastern Foxsnake, which is an endangered species. Jimmy was illegally taken from his natural home to live in an apartment, during which time he became thoroughly domesticated. Jimmy has now lived in the park’s visitor centre for 11 years and he loves to be handled by visitors.

 

Jimmy, an Eastern Foxsnake

Jimmy enjoying a snuggle!

View along Georgian Bay at Killbear park.

Our group then headed out for a walk along the Georgian Bay shore to learn all about lichens. Our guide Jessica had done extensive research to prepare for our learned group. While Jessica pointed out various species of lichens, she told us many interesting facts about them: the symbiotic relationship (or not?) between a fungus and a photosynthetic parter (green algae or cyanobacterium); their classification and distribution; modes of reproduction; their chemistry and finally applications, such as dyes.

For me the most provocative fact was that 3 species of lichens are able to degrade the toxic form of prions, which normally are very resistant to degradation. Yes, lichens have prions, though since they have no central nervous system they are not subject to the diseases that prions can cause. So why would some specific lichens be able to degrade toxic prions?

Some leafy lichens

 

Very bright green lichens!

 

Strange black lichens

Kayaking on Georgian Bay

The morning group kayaking on Georgian Bay.

After a picnic on the beach, it was my group’s turn to go out kayaking on the bay, in tandem boats (excuse me, kayaks!). After a quick tutorial on how to put on the “skirt” that seals you into the kayak (our first challenge), how to paddle, and the responsibilities of each team member (brawn in the front, brains in the back—of course I was in the back for lack of the former), we set off for some exercise.

And exercise it was! Many of us had opted to kayak in the afternoon, thinking it would be warmer and indeed it was. However, the wind had come up in the early afternoon, leading to choppy water and a much harder row for those of us out there. We didn’t make it as far as the morning group, and on our way back, against the wind, the shore seemed to remain out of reach, until we finally arrived. And that is when it happened—trying to get out of the kayak I didn’t coordinate very well with my partner and ended up “sitting down” in the water. Yikes!

Finally, some relaxation: time for a BBQ and convivial talk to end the day, before returning to Parry Sound.

If there’s one word that characterises Martin, it has to be energy—boundless energy—and one needs plenty of it to keep up with him, even in fun!

A view of Georgian Bay at Killbear Park Myself on the rocky shore of Georgian Bay Killbear Park shore

All photos copyright Denise Parent

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NJC at CanBIC-4 in Ontario

Stockey Centre for the Performing Arts in Parry Sound

Stockey Centre for the Performing Arts in Parry Sound, location for the CanBIC conferences

I arrived in Parry Sound on Georgian Bay, after flying into Toronto and taking a long bus ride up north, to promote NJC at the 4th Georgian Bay International Conference on Bioinorganic Chemistry. NJC was a major sponsor this year, providing support for the student volunteers who are “on call” to ensure that the conference runs smoothly.

This year’s event brought together about 140 scientists: about two-thirds from North America with the other participants being mainly from Europe and Japan.

This is not a conference for the weak-of-heart: the conference organisers (Martin Stillman, Nagao Kobayashi, C Frank Shaw III) put together a very full and challenging program combining science and fun in a beautiful natural setting.

Conference organizers Frank, Martin and Nagao, windblown on the Island Queen cruise boat.

Sunset behind the Stockey Centre Lilacs in bloom in Parry Sound Georgian Bay shore behind Stockey Centre

The science consisted of 90 talks (3 parallel sessions over 3 days), which ranged from the physical techniques, synthesis and properties, to medical applications. Ed Solomon‘s plenary lecture on copper–dioxygen reactivity closed the conference, while over 30 posters completed the program.

My favourite talks were those given by Wojciech Bal (U Warsaw) on nickel toxicity, Kyung-Bin Cho (Ewha Womans U) on rebound reactions in non-heme systems, Andrew Cammidge (U East Anglia) on Pcs-Por hybrids, Peter Caravan (Harvard Medical School) on MRI probes, Tim Storr (Simon Fraser U) on treating Alzheimer’s disease, Danny Leznoff (also at SFU) on metallo-Pcs, Jennifer Wytko (U Strasbourg) on porphyrin wires and Ian Butler (McGill U) on analysing artists’ pigments.
The fun included a boat cruise on the bay (a welcome and relaxing break), two music recitals in the evening, and an after-conference all-day outing to Killbear Provincial Park for hiking, kayaking and a BBQ. (More on the outing in an upcoming post, with photos.)

Island Queen cruise ship in Parry Sound Hole in the Wall passage in Georgian Bay Lighthouse on Georgian Bay

The cruise on the Island Queen was a welcome and relaxing break—staying warm inside the boat with occasional forays outside for photo ops.

The CanBIC conferences also feature music, provided by Katie Stillman on violin and Miaomiao Yu on piano. These two young talented musicians have played together for many years, which was evident from their perfect harmony in pieces ranging from Mozart to 20th century composers.

After this informal and small conference out in the woods, next week will be a complete change of scenery as I’m off to the 96th Canadian Society of Chemistry conference in Quebec City. Check back for my comments on this event.

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Where to meet the NJC team in 2013

Will you be attending one of the following conferences at which one of the NJC Editors will also be present? 

 Symposium on Foldamers — 10–12 April, Paris (France) — meet Laurent
Journées Scientifiques SCF: Section PACA — 11 April, Nice (France) — meet Ling
4th Georgian Bay International Conference on Bioinorganic Chemistry —21–25 May, Parry Sound (Canada) — meet Denise
96th Canadian Chemistry Conference — 26–30 May, Quebec City (Canada) — meet Denise
GECOM-Concoord — 26–31 May, Cap d’Agde (France) — meet Yannick
5th European Conference Chemistry for Life Sciences (5ECCLS) — 10–12 June, Barcelona (Spain) — meet Eva
The 8th International Dendrimer Symposium (IDS-8) — 23–27 June, Madrid (Spain) — meet Ling
20th EuCheMS Conference on Organometallic Chemistry (EuCOMC) — 30 June–4 July, St Andrews (UK) — meet Denise
18th European Symposium on Organic Chemistry (ESOC) — 7–12 July, Marseille (France) — meet Ling
International Conference on Advanced Complex Inorganic Nanomaterials — 15–19 July, Namur (Belgium) — meet Denise
XIV European Symposium on Organic Reactivity (ESOR) — 1–6 September, Prague (Czech Republic) — meet Eva
Organometallic & Coordination Chemistry: Fundamental and Applied Aspects — 1–7 September, cruise on Volga & Sheksna Rivers from Nizhny Novgorod (Russia) — meet Yannick
International Conference on Nanoscience & Technology (ChinaNANO) — 5–7 September, Beijing (China) — meet Ling
5th BBBB Drug Delivery — 26–28 September, Athens (Greece) — meet Ling
ILMAT 2013 — 18–20 November, Montpellier (France) — meet Yannick 

More details on what we’ll be doing at these meetings will be posted on the blog in the coming months — keep an eye on this space to find out more.
 

Do drop us a line if you’ll be there too — we’d enjoy meeting you!

Denise Parent (Editor), Eva Balentova (Deputy Editor), Yannick Guari, Ling Peng and Laurent Vial (Assistant Editors)

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The last of 2012’s NJC Poster Prize winners

Yang Wang

 Yang Wang, a young Chinese Ph.D. student in the group of Dr Ling Peng at the CINaM in Marseille, won the NJC Poster Prize awarded at the 7th Organic Chemistry Meeting of Marseille. His research interests lie in synthesizing different kinds of dendrimers and their bio-application in drug delivery, especially nucleic acids drug delivery.  

Yang’s winning poster was entitled  “Synthesis of amphiphilic poly(aminoester) dendrimers  for drug delivery”. Poly(aminoester) dendrimers show great promise as biodegradable nanocarriers for drug delivery due to their advantageous properties: biodegradability, potentially lower toxicity and possibility of diverse chemical conjugations. This work presented the design and synthesis of amphiphilic poly(aminoester) dendrimers bearing amine terminal functionalities for effective drug delivery.  

Konstantin Chegaev

 Two NJC poster prizes were awarded at the 6th French-Italian Chemistry Days, also held in Marseille and organized under the auspices of the French Chemical Society (SCF).  

Dr Konstantin Chegaev is a researcher in the group of Prof. Roberta Fruttero, in the Department of Pharmaceutical Science and Technology of the University of Torino. He is focusing his research in the field of anticancer drugs with particular interest to the problem of multi-drug resistance.  

The title of Konstantin’s poster was “Multitarget drugs: NO-donor doxorubicins”. The major result presented in this work is the reversal of multitarget drug resistance in doxorubicin-resistant cell lines. The use of exogenous NO-donor molecules provoke the nitration of tyrosine residue of MDR pumps with consequent increase of doxorubicin accumulation and toxicity in HT29dx cell lines. The authors believe that NO-donor doxorubicins warrant further investigations in preclinical and clinical settings.  

Momar Toure

  

Ph.D. student Momar Toure was the 2nd laureate at this meeting. He is completing his studies in the groups of Jean-Luc Parrain and Olivier Chuzel in the iSm2 laboratory at the University of Aix-Marseille.  

Momar’s poster was on “Self-assembled calixborate macrocyclic anion receptors“. Well-designed macrocyclic calixborates  incorporating imidazolium functinalities were synthesized in high yield. These new macrocycles display a high binding affinity for halides and oxoanions.  

Congratulations to all 3 laureates!
  

A list of all previous NJC Poster Prize winners can be found here.

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NJC at the first ERC Grantees Conference

I attended the first ERC Grantees Conference at the Council of Europe in Strasbourg last month, to hear about the research of recent winners of ERC starting and advanced grants in chemistry. The conference was proposed and organized by two chemists at the Institut Charles Sadron of Strasbourg: Nicolas Giuseppone and Jean-François Lutz.

 

The first two days began with plenary lectures by Jean-Marie Lehn and Ben Feringa, sponsored by Angewandte Chemie (Wiley) and NJC (RSC), respectively. The presentations by 24 grantees of the 2007–2011 grant period were strongly oriented towards complex systems, both chemical and biological.

 

European Research Council officials were also on hand to present the grants program and give an update on what to expect in the coming proposal period.

 

Sightseeing boat in front of the European Parlement.

Conference participants board the sightseeing boat in front of the European Parlement that will take them to the conference dinner.

On Friday evening, a boat ride on the Ill river flowing through the center of Strasbourg took participants to the conference dinner held at the historic Maison Kammerzell, next to the cathedral.

 

The next morning, the younger participants eagerly awaited the announcement of the four poster prizes, provided by three scientific publishers (Nature, Wiley and the RSC for NJC). Dr Yan-Jun Liu, a postdoctoral fellow in the group of Damien Baigl (Ecole Normale Supérieure, Paris) won the NJC prize. Her poster was entitled “High-yield preparation of proteo-liposomes: a synthetic biology approach”.

(more…)

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NJC Poster Prizes at Biodendrimers Symposium

NJC sponsored two poster prizes at the recent 3rd International Symposium on Biological Applications of Dendrimers, held in Toledo, Spain at the beginning of September. Below I present the winners.

Ladies first! Franka Ennen is a 2nd year Ph.D. student in the group of Dietmar Appelhans and Brigitte Voit at the Leibniz Institute for Polymerresearch (IPF) Dresden, Germany. The group is interested in gaining a fundamental understanding of the interactions of natural and synthetic macromolecules such as dendritic glycopolymers or novel proteins for various applications. Franka chose to do her research thesis work at the IPR so as to acquire expertise in various physical/microscopic techniques such as TEM and AFM.

In her poster, “Uptake Behaviour of Oligosaccharide Modified Hyperbranched Poly(ethyleneimine) with Various Watersoluble B-Vitamins” Franka addressed the application of hyperbranched glycopolymers as chromatographic selectors and showed promising first results of oligosaccharide modified poly(ethylene imines) as stationary phases for selective and efficient separation in a chromatographic process, specifically capillary electrochromatography. This work was a collaboration between the IPF and Prof. Dr. Ludmila Anna Kartsova from the State University in St. Petersburg, Russia.

The second winner is Pablo Mesa Antúnez, also a 2nd year graduate student. After a first degree in chemistry and a Masters thesis on luminescent doped silica nanoparticles, Pablo is continuing his studies at the University of Malaga, in the Biomimetic Dendrimers and Photonic Laboratory. His research, supported by an FPI grant from the Spanish government and carried out under the supervision of Ezequiel Perez-Inestrosa, is focused on the development of new dendrimers based on amide bonds and with amine-terminal groups for biomedical applications.

Pablo’s poster on the “Synthesis of New Amine-terminal Dendrimers. The Alternative Henry Approach”, highlights precisely the possibilities given by the Henry approach in the synthesis of dendrimers to obtain different structures and the relatively easy way to obtain the sought-for dendrimer with the azide approach.

The symposium organizers also awarded a poster prize to Rosa M. Reguera, professor in the Department of Biomedical Sciences of the Veterinary School of the University of León in Spain, for her poster entitled “Carbosilane Dendrimers as Chemotherapy against Leishmania Parasite”. With her collaborators, Rosa has developed an in vitro high throughput screening system, which is based on genetically engineered Leishmania strains that emit infrared fluorescence in living cells, to test hundreds of potential antileishmanial compounds.

Collaborators include the Immune-Molecular Department headed by Dra. Muñoz-Fernández of General Hospital Gregorio Marañon in Madrid and Drs De La Mata and Gomez of the Inorganic Chemistry Department at the Universidad de Alcalá (Alcalá de Henares, Madrid). In their winning poster, carbosilane dendrimers were used as a drug delivery system to potentiate the therapeutic effect of antileishmanial drugs.

Congratulations to all of the winners for their excellent work, and we wish them continuing success in their research!

3 prize winners with editor and symposium organizer

From left to right: winners Rosa M Reguera (University of León) and Pablo Mesa-Antúnez (University of Malaga), NJC editor Denise Parent (CNRS Montpellier), organizer Rafael Gómez-Ramírez (University of Alcalá) and winner Franka Ennen (IFP Leibniz).

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