October issue of NJC out now!

We are pleased to introduce you to our latest issue. Whether you are a material, synthetic or biological chemist, you are guaranteed to find articles of relevance to your specialist interests.

The outside front cover highlights a paper by Katharina Fucke and co-workers (University of Durham, UK) and collaborators, reporting a comparative study of co-crystallisation methods for obtaining new co-crystal forms of a model drug compound with twenty different carboxylic acids. A total of 46 co-crystal forms of Piroxicam, a non-steroidal anti-inflammatory drug, were obtained. The authors offer several thoughts on how their results might usefully be applied to co-crystal screens in order to improve the solubility and/or dissolution rate of pharmaceutical drugs.

“How good are the crystallisation methods for co-crystals? A comparative study of piroxicam”, Katharina Fucke, Svetlana A. Myz, Tatyana P. Shakhtshneider, Elena V. Boldyreva and Ulrich J. Griesser New J. Chem., 2012, 36, 1969-1977, DOI: 10.1039/C2NJ40093F.

The inside front cover was produced by Marian R. Davolos and co-workers (Universidade Estadual Paulista, Araraquara, Brazil). In this paper, the authors describe the synthesis and characterization of the amphiphilic europium complex [(C12H25)2(CH3)2N][Eu(tta)4], along with the formation of stable Langmuir monolayers at the air/water interface. The molecular arrangement at the air/water interface and the preserved luminescence in the Langmuir–Blodgett films were consistent with theoretical predictions. This luminescent and amphiphilic complex could be used as a probe when incorporated in Langmuir monolayers of phospholipids or other surfactants that mimic cell membranes.

“Synthesis of a functionalized europium complex and deposition of luminescent Langmuir–Blodgett (LB) films”, Renata D. Adati, Felippe J. Pavinatto, Jorge H. S. K. Monteiro, Marian R. Davolos, Miguel Jafelicci and Osvaldo N. Oliveira New J. Chem., 2012, 36, 1978-1984, DOI: 10.1039/C2NJ40199A

You can access and read the whole issue 10 of NJC here. Leave us a comment and let us know what you think!

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