Lab on a Chip Blog

This month sees the following articles in Lab on a Chip that are in the top ten most accessed:

Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care
ShuQi Wang, Xiaohu Zhao, Imran Khimji, Ragip Akbas, Weiliang Qiu, Dale Edwards, Daniel W. Cramer, Bin Ye and Utkan Demirci
Lab Chip, 2011, 11, 3411-3418
DOI: 10.1039/C1LC20479C

Paper on a disc: balancing the capillary-driven flow with a centrifugal force
Hyundoo Hwang, Seung-Hoon Kim, Tae-Hyeong Kim, Je-Kyun Park and Yoon-Kyoung Cho
Lab Chip, 2011, Advance Article
DOI: 10.1039/C1LC20445A

Microfluidics with aqueous two-phase systems
Steffen Hardt and Thomas Hahn
Lab Chip, 2011, Advance Article
DOI: 10.1039/C1LC20569B

Large-scale plasmonic microarrays for label-free high-throughput screening
Tsung-Yao Chang, Min Huang, Ahmet Ali Yanik, Hsin-Yu Tsai, Peng Shi, Serap Aksu, Mehmet Fatih Yanik and Hatice Altug
Lab Chip, 2011, 11, 3596-3602
DOI: 10.1039/C1LC20475K

Education: A modular approach to microfluidics in the teaching laboratory
Yolanda Fintschenko
Lab Chip, 2011, 11, 3394-3400
DOI: 10.1039/C1LC90069B

Automated high-throughput generation of droplets
Jan Guzowski, Piotr M. Korczyk, Slawomir Jakiela and Piotr Garstecki
Lab Chip, 2011, 11, 3593-3595
DOI: 10.1039/C1LC20595A

Rounded multi-level microchannels with orifices made in one exposure enable aqueous two-phase system droplet microfluidics
David Lai, John P. Frampton, Hari Sriram and Shuichi Takayama
Lab Chip, 2011, 11, 3551-3554
DOI: 10.1039/C1LC20560A

Microchip-based immunomagnetic detection of circulating tumor cells
Kazunori Hoshino, Yu-Yen Huang, Nancy Lane, Michael Huebschman, Jonathan W. Uhr, Eugene P. Frenkel and Xiaojing Zhang
Lab Chip, 2011, Advance Article
DOI: 10.1039/C1LC20270G

A digital microfluidic method for dried blood spot analysisMais J. Jebrail, Hao Yang, Jared M. Mudrik, Nelson M. Lafrenière, Christine McRoberts, Osama Y. Al-Dirbashi, Lawrence Fisher, Pranesh Chakraborty and Aaron R. Wheeler
Lab Chip, 2011, 11, 3218-3224
DOI: 10.1039/C1LC20524B

Green microfluidic devices made of corn proteins
Jarupat Luecha, Austin Hsiao, Serena Brodsky, Gang Logan Liu and Jozef L. Kokini
Lab Chip, 2011, 11, 3419-3425
DOI: 10.1039/C1LC20726A

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Lab on a Chip that are in the top ten most accessed:

Automated cellular sample preparation using a Centrifuge-on-a-Chip
Albert J. Mach, Jae Hyun Kim, Armin Arshi, Soojung Claire Hur and Dino Di Carlo
Lab Chip, 2011, 11, 2827-2834
DOI: 10.1039/C1LC20330D

Benchtop micromolding of polystyrene by soft lithography
Yuli Wang, Joseph Balowski, Colleen Phillips, Ryan Phillips, Christopher E. Sims and Nancy L. Allbritton
Lab Chip, 2011, 11, 3089-3097
DOI: 10.1039/C1LC20281B

Next-generation integrated microfluidic circuits
Bobak Mosadegh, Tommaso Bersano-Begey, Joong Yull Park, Mark A. Burns and Shuichi Takayama
Lab Chip, 2011, 11, 2813-2818
DOI: 10.1039/C1LC20387H

Beyond PDMS: off-stoichiometry thiol–ene (OSTE) based soft lithography for rapid prototyping of microfluidic devices
Carl Fredrik Carlborg, Tommy Haraldsson, Kim Öberg, Michael Malkoch and Wouter van der Wijngaart
Lab Chip, 2011, 11, 3136-3147
DOI: 10.1039/C1LC20388F

A high-performance microsystem for isolating circulating tumor cells
Xiangjun Zheng, Luthur Siu-Lun Cheung, Joyce A. Schroeder, Linan Jiang and Yitshak Zohar
Lab Chip, 2011, 11, 3269-3276
DOI: 10.1039/C1LC20331B

Paper on a disc: balancing the capillary-driven flow with a centrifugal force
Hyundoo Hwang, Seung-Hoon Kim, Tae-Hyeong Kim, Je-Kyun Park and Yoon-Kyoung Cho
Lab Chip, 2011, Advance Article
DOI: 10.1039/C1LC20445A

Double-emulsion drops with ultra-thin shells for capsule templates
Shin-Hyun Kim, Jin Woong Kim, Jun-Cheol Cho and David A. Weitz
Lab Chip, 2011, 11, 3162-3166
DOI: 10.1039/C1LC20434C

Rapid spatial and temporal controlled signal delivery over large cell culture areas
Jules J. VanDersarl, Alexander M. Xu and Nicholas A. Melosh
Lab Chip, 2011, 11, 3057-3063
DOI: 10.1039/C1LC20311H

Flexible microfluidic devices with three-dimensional interconnected microporous walls for gas and liquid applications
Po Ki Yuen and Michael E. DeRosa
Lab Chip, 2011, 11, 3249-3255
DOI: 10.1039/C1LC20157C

Microchip-based immunomagnetic detection of circulating tumor cells
Kazunori Hoshino, Yu-Yen Huang, Nancy Lane, Michael Huebschman, Jonathan W. Uhr, Eugene P. Frenkel and Xiaojing Zhang
Lab Chip, 2011, Advance Article
DOI: 10.1039/C1LC20270G

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This month sees the following articles in Lab on a Chip that are in the top ten most accessed:

Disposable microfluidic substrates: Transitioning from the research laboratory into the clinic
Jason S. Kuo and Daniel T. Chiu
Lab Chip, 2011, 11, 2656-2665
DOI: 10.1039/c1lc20125e

‘Fab-Chips’: a versatile, fabric-based platform for low-cost, rapid and multiplexed diagnostics
Paridhi Bhandari, Tanya Narahari and Dhananjaya Dendukuri
Lab Chip, 2011, 11, 2493-2499
DOI: 10.1039/c1lc20373h

Photoreversible fragmentation of a liquid interface for micro-droplet generation by light actuation
Antoine Diguet, Hao Li, Nicolas Queyriaux, Yong Chen and Damien Baigl
Lab Chip, 2011, 11, 2666-2669
DOI: 10.1039/c1lc20328b

Integrated microfluidic array plate (iMAP) for cellular and molecular analysis
Ivan K. Dimov, Gregor Kijanka, Younggeun Park, Jens Ducrée, Taewook Kang and Luke P. Lee
Lab Chip, 2011, 11, 2701-2710
DOI: 10.1039/c1lc20105k

A self-heating cartridge for molecular diagnostics
Changchun Liu, Michael G. Mauk, Robert Hart, Xianbo Qiu and Haim H. Bau
Lab Chip, 2011, 11, 2686-2692
DOI: 10.1039/c1lc20345b

Integrated immunoassay using tuneable surface acoustic waves and lensfree detection
Yannyk Bourquin, Julien Reboud, Rab Wilson, Yi Zhang and Jonathan M. Cooper
Lab Chip, 2011, 11, 2725-2730
DOI: 10.1039/c1lc20320g

Research highlights
Šeila Selimović and Ali Khademhosseini
Lab Chip, 2011, 11, 2651-2652
DOI: 10.1039/c1lc90074a

Microfluidic fluorescence in situ hybridization and flow cytometry (µFlowFISH)
Peng Liu, Robert J. Meagher, Yooli K. Light, Suzan Yilmaz, Romy Chakraborty, Adam P. Arkin, Terry C. Hazen and Anup K. Singh
Lab Chip, 2011, 11, 2673-2679
DOI: 10.1039/c1lc20151d

DNA detection with a polymeric nanochannel device
Paola Fanzio, Valentina Mussi, Chiara Manneschi, Elena Angeli, Giuseppe Firpo, Luca Repetto and Ugo Valbusa
Lab Chip, 2011, 11, 2961-2966
DOI: 10.1039/c1lc20243j

Paper-based piezoresistive MEMS sensors
Xinyu Liu, Martin Mwangi, XiuJun Li, Michael O’Brien and George M. Whitesides
Lab Chip, 2011, 11, 2189-2196
DOI: 10.1039/c1lc20161a

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Lab on a Chip that are in the top ten most accessed:

Inkjet-like printing of single-cells
Azmi Yusof, Helen Keegan, Cathy D. Spillane, Orla M. Sheils, Cara M. Martin, John J. O’Leary, Roland Zengerle and Peter Koltay
Lab Chip, 2011, 11, 2447-2454
DOI: 10.1039/C1LC20176J

A lab-on-a-chip for rapid blood separation and quantification of hematocrit and serum analytes
Andrew W. Browne, Lakshminarayanan Ramasamy, Timothy P. Cripe and Chong H. Ahn
Lab Chip, 2011, 11, 2440-2446
DOI: 10.1039/C1LC20144A

A microfluidic platform for high-sensitivity, real-time drug screening on C. elegans and parasitic nematodes
John A. Carr, Archana Parashar, Richard Gibson, Alan P. Robertson, Richard J. Martin and Santosh Pandey
Lab Chip, 2011, 11, 2385-2396
DOI: 10.1039/C1LC20170K

The construction of an individually addressable cell array for selective patterning and electroporation
Youchun Xu, Huanfen Yao, Lei Wang, Wanli Xing and Jing Cheng
Lab Chip, 2011, 11, 2417-2423
DOI: 10.1039/C1LC20183B

Integrated and diffusion-based micro-injectors for open access cell assays
Xin Li, Li Liu, Li Wang, Ken-ichiro Kamei, Qinghua Yuan, Fan Zhang, Jian Shi, Akihiro Kusumi, Min Xie, Zhenjie Zhao and Yong Chen
Lab Chip, 2011, 11, 2612-2617
DOI: 10.1039/C1LC20258H

Massively parallel sequencing platforms using lab on a chip technologies
Afshin Ahmadian and Helene Andersson Svahn
Lab Chip, 2011, 11, 2653-2655
DOI: 10.1039/C1LC90035H

Pneumatically tunable optofluidic 2 × 2 switch for reconfigurable optical circuit
Wuzhou Song and Demetri Psaltis
Lab Chip, 2011, 11, 2397-2402
DOI: 10.1039/C1LC20220K

Reactions in double emulsions by flow-controlled coalescence of encapsulated drops
Haosheng Chen, Yuanjin Zhao, Jiang Li, Ming Guo, Jiandi Wan, David A. Weitz and Howard A. Stone
Lab Chip, 2011, 11, 2312-2315
DOI: 10.1039/C1LC20265K

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics
Deniz Pekin, Yousr Skhiri, Jean-Christophe Baret, Delphine Le Corre, Linas Mazutis, Chaouki Ben Salem, Florian Millot, Abdeslam El Harrak, J. Brian Hutchison, Jonathan W. Larson, Darren R. Link, Pierre Laurent-Puig, Andrew D. Griffiths and Valérie Taly
Lab Chip, 2011, 11, 2156-2166
DOI: 10.1039/C1LC20128J

In situ dynamic measurements of the enhanced SERS signal using an optoelectrofluidic SERS platform
Hyundoo Hwang, Dongsik Han, Young-Jae Oh, Yoon-Kyoung Cho, Ki-Hun Jeong and Je-Kyun Park
Lab Chip, 2011, 11, 2518-2525
DOI: 10.1039/C1LC20277D

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Lab on a Chip? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Lab on a Chip that are in the top ten most accessed:-

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics
Deniz Pekin, Yousr Skhiri, Jean-Christophe Baret, Delphine Le Corre, Linas Mazutis, Chaouki Ben Salem, Florian Millot, Abdeslam El Harrak, J. Brian Hutchison, Jonathan W. Larson, Darren R. Link, Pierre Laurent-Puig, Andrew D. Griffiths and Valérie Taly
Lab Chip, 2011, 11, 2156-2166
DOI: 10.1039/C1LC20128J

Paper-based piezoresistive MEMS sensors
Xinyu Liu, Martin Mwangi, XiuJun Li, Michael O’Brien and George M. Whitesides
Lab Chip, 2011, 11, 2189-2196
DOI: 10.1039/C1LC20161A

Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR
Qun Zhong, Smiti Bhattacharya, Steven Kotsopoulos, Jeff Olson, Valérie Taly, Andrew D. Griffiths, Darren R. Link and Jonathan W. Larson
Lab Chip, 2011, 11, 2167-2174
DOI: 10.1039/C1LC20126C

Micromolding of solvent resistant microfluidic devices
Theodorus J. A. Renckens, Dainius Janeliunas, Hilbert van Vliet, Jan H. van Esch, Guido Mul and Michiel T. Kreutzer
Lab Chip, 2011, 11, 2035-2038
DOI: 10.1039/C0LC00550A

Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation
Ali Asgar S. Bhagat, Han Wei Hou, Leon D. Li, Chwee Teck Lim and Jongyoon Han
Lab Chip, 2011, 11, 1870-1878
DOI: 10.1039/C0LC00633E

Systematic investigation of droplet generation at T-junctions
Thomas Schneider, Daniel R. Burnham, Jaylen VanOrden and Daniel T. Chiu
Lab Chip, 2011, 11, 2055-2059
DOI: 10.1039/C1LC20259F

Stand-alone self-powered integrated microfluidic blood analysis system (SIMBAS)
Ivan K. Dimov, Lourdes Basabe-Desmonts, Jose L. Garcia-Cordero, Benjamin M. Ross, Antonio J. Ricco and Luke P. Lee
Lab Chip, 2011, 11, 845-850
DOI: 10.1039/C0LC00403K

Mixing enhancement for high viscous fluids in a microfluidic chamber
Shasha Wang, Xiaoyang Huang and Chun Yang
Lab Chip, 2011, 11, 2081-2087
DOI: 10.1039/C0LC00695E

Miniature magnetic resonance system for point-of-care diagnostics
David Issadore, Changwook Min, Monty Liong, Jaehoon Chung, Ralph Weissleder and Hakho Lee
Lab Chip, 2011, 11, 2282-2287
DOI: 10.1039/C1LC20177H

On-chip background noise reduction for cell-based assays in droplets
Pascaline Mary, Angela Chen, Irwin Chen, Adam R. Abate and David A. Weitz
Lab Chip, 2011, 11, 2066-2070
DOI: 10.1039/C1LC20159J

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Lab on a Chip that are in the top ten most accessed:-

Miniaturized isothermal nucleic acid amplification, a review 
Peter J. Asiello and Antje J. Baeumner 
Lab Chip, 2011, 11, 1420-1430, DOI: 10.1039/C0LC00666A, Critical Review 

Stand-alone self-powered integrated microfluidic blood analysis system (SIMBAS) 
Ivan K. Dimov, Lourdes Basabe-Desmonts, Jose L. Garcia-Cordero, Benjamin M. Ross, Antonio J. Ricco and Luke P. Lee 
Lab Chip, 2011, 11, 845-850, DOI: 10.1039/C0LC00403K, Paper 

A software-programmable microfluidic device for automated biology 
Luis M. Fidalgo and Sebastian J. Maerkl 
Lab Chip, 2011, 11, 1612-1619, DOI: 10.1039/C0LC00537A, Paper 

Elastomeric membrane valves in a disc 
Hyundoo Hwang, Hak-Hyeon Kim and Yoon-Kyoung Cho 
Lab Chip, 2011, 11, 1434-1436, DOI: 10.1039/C0LC00658K, Communication 

Phaseguides: a paradigm shift in microfluidic priming and emptying 
Paul Vulto, Susann Podszun, Philipp Meyer, Carsten Hermann, Andreas Manz and Gerald A. Urban 
Lab Chip, 2011, 11, 1596-1602, DOI: 10.1039/C0LC00643B, Paper 

Microparticle and cell counting with digital microfluidic compact disc using standard CD drive 
Syed M. Imaad, Nathan Lord, Gulsim Kulsharova and Gang Logan Liu 
Lab Chip, 2011, 11, 1448-1456, DOI: 10.1039/C0LC00451K, Paper 

Capillary-driven automatic packaging 
Yuzhe Ding, Lingfei Hong, Baoqing Nie, Kit S. Lam and Tingrui Pan 
Lab Chip, 2011, 11, 1464-1469, DOI: 10.1039/C0LC00710B, Paper 

Three-dimensional interconnected microporous poly(dimethylsiloxane) microfluidic devices 
Po Ki Yuen, Hui Su, Vasiliy N. Goral and Katherine A. Fink 
Lab Chip, 2011, 11, 1541-1544, DOI: 10.1039/C0LC00660B, Technical Note 

Nanolitre droplet array for real time reverse transcription polymerase chain reaction 
Yunxia Zhang, Ying Zhu, Bo Yao and Qun Fang 
Lab Chip, 2011, 11, 1545-1549, DOI: 10.1039/C0LC00502A, Technical Note 

A magnetic bead-based assay for the rapid detection of methicill
Chih-Hung Wang, Kang-Yi Lien, Jiunn-Jong Wu and Gwo-Bin Lee
Lab Chip, 2011, 11, 1521-1531, DOI: 10.1039/C0LC00430H, Paper

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Lab on a Chip? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Lab on a Chip that are in the top ten most accessed:-

Microfluidics and complex fluids 
Ph Nghe, E. Terriac, M. Schneider, Z. Z. Li, M. Cloitre, B. Abecassis and P. Tabeling 
Lab Chip, 2011, 11, 788-794, DOI: 10.1039/C0LC00192A, Tutorial Review 

Rapid prototyping of microstructures in polydimethylsiloxane (PDMS) by direct UV-lithography 
Tim Scharnweber, Roman Truckenmüller, Andrea M. Schneider, Alexander Welle, Martina Reinhardt and Stefan Giselbrecht 
Lab Chip, 2011, 11, 1368-1371, DOI: 10.1039/C0LC00567C, Technical Note 

Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP) 
Hui-Sung Moon, Kiho Kwon, Seung-Il Kim, Hyunju Han, Joohyuk Sohn, Soohyeon Lee and Hyo-Il Jung 
Lab Chip, 2011, 11, 1118-1125, DOI: 10.1039/C0LC00345J, Paper 

nanoLAB: An ultraportable, handheld diagnostic laboratory for global health 
Richard S. Gaster, Drew A. Hall and Shan X. Wang 
Lab Chip, 2011, 11, 950-956, DOI: 10.1039/C0LC00534G, Paper 

Programmed trapping of individual bacteria using micrometre-size sieves 
Min-Cheol Kim, Brett C. Isenberg, Jason Sutin, Amit Meller, Joyce Y. Wong and Catherine M. Klapperich 
Lab Chip, 2011, 11, 1089-1095, DOI: 10.1039/C0LC00362J, Paper 

Lab-on-a-chip based immunosensor principles and technologies for the detection of cardiac biomarkers: a review 
Mazher-Iqbal Mohammed and Marc P. Y. Desmulliez 
Lab Chip, 2011, 11, 569-595, DOI: 10.1039/C0LC00204F, Tutorial Review 

Simple room temperature bonding of thermoplastics and poly(dimethylsiloxane) 
Vijaya Sunkara, Dong-Kyu Park, Hyundoo Hwang, Rattikan Chantiwas, Steven A. Soper and Yoon-Kyoung Cho 
Lab Chip, 2011, 11, 962-965, DOI: 10.1039/C0LC00272K, Technical Note 

Stand-alone self-powered integrated microfluidic blood analysis system (SIMBAS) 
Ivan K. Dimov, Lourdes Basabe-Desmonts, Jose L. Garcia-Cordero, Benjamin M. Ross, Antonio J. Ricco and Luke P. Lee 
Lab Chip, 2011, 11, 845-850, DOI: 10.1039/C0LC00403K, Paper 

Integrated systems for rapid point of care (PoC) blood cell analysis 
Cees van Berkel, James D. Gwyer, Steve Deane, Nicolas Green, Judith Holloway, Veronica Hollis and Hywel Morgan 
Lab Chip, 2011, 11, 1249-1255, DOI: 10.1039/C0LC00587H, Paper 

Affinity reagents for lab on chips 
Mathias Uhlen and Helene Andersson Svahn 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C1LC90005F, Focus 

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